Publications by authors named "Wei B Xia"
Article Synopsis
- The study aimed to explore how variations in the LRP5 gene affect the effectiveness of alendronate treatment in women with osteoporosis in China.
- The research involved 639 postmenopausal women who were treated with alendronate, and the A1330V polymorphism in LRP5 was examined alongside changes in bone mineral density and bone turnover markers before and after treatment.
- Results showed that women with CC and CT genotypes experienced more significant improvements in lumbar spine bone density and decreases in specific bone turnover markers than those with the TT genotype, indicating that the TT genotype may signal a weaker response to the medication.
Background: A vast amount of literature describes the incidence of fracture as a risk for recurrent osteoporotic fractures in western and Asian countries. Osteoporosis evaluation and treatment after a low-trauma fracture, however, has not been well characterized in postmenopausal women in Asia. The purpose of this study was to characterize patient and health system characteristics associated with the diagnosis and management of osteoporosis among postmenopausal women hospitalized with a fragility fracture in Asia.
View Article and Find Full Text PDF