Publications by authors named "Wedad S Aboussahoud"
Hum Reprod
September 2021
Article Synopsis
- The innate immune system is active in early human embryo development, with pattern recognition receptors and Toll-like receptor (TLR) genes being expressed in preimplantation embryos.
- The study utilized transcriptome data and experiments on Day 5 embryos, exposing them to TLR ligands to measure gene expression and cytokine production.
- Results indicated significant expression of various TLR genes, especially TLRs 9 and 5 in blastocysts, suggesting that human embryos can respond to environmental immune signals.
