Publications by authors named "Wbeimar Andrey Rivera-Perez"
Arch Oral Biol
February 2019
Article Synopsis
- The study explored compounds that could inhibit the phosphoenolpyruvate-sugar phosphotransferase system in S. mutans, focusing on the enzyme II mannose transporter subunits (IIA, IIB, and IIC).
- Intervening in this system could impact the behavior and pathogenicity of S. mutans and other bacteria, making it a potential target for treating dental caries.
- Thirteen compounds were identified with favorable characteristics for inhibiting the phosphotransferase system, including six spirooxindoles and three pyrrolidones, which have unique biological activities and potential therapeutic applications.
