Publications by authors named "Wayne Ren See"
Article Synopsis
- The development of genome-scale genetic screening methods like CRISPR knockout screens has significantly enhanced our understanding of how viruses interact with their hosts.
- This review explores the impact of CRISPR screening on identifying novel host factors for various viruses, discussing its experimental design and key findings.
- The authors also provide insights on customizing CRISPR methods for specific research questions and present examples, including flaviviruses and SARS-CoV-2, to illustrate the capabilities of these techniques in virus-host interaction studies.
High-throughput experiments often produce ranked gene outputs, with forward genetic screening being a notable example. While there are various tools for analyzing individual datasets, those that perform comparative and meta-analytical examination of such ranked gene lists remain scarce. Here, we introduce Gene Rank Meta Analyzer (GeneRaMeN), an R Shiny tool utilizing rank statistics to facilitate the identification of consensus, unique, and correlated genes across multiple hit lists.
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