Skin Barrier Parameters in Acne Vulgaris versus Normal Controls: A Cross-Sectional Analytic Study.

Aim: Data of objective skin barrier parameters in acne patients with and without therapy compared with normal controls are limited. This information could provide more insight into the pathogenesis of acne vulgaris and optimal acne treatment.

Purpose: To measure and compare skin barrier parameters in a large cohort of acne patients with and without therapy compared with normal controls.

Evaluation of an Acne Severity Grading Self-Assessment System Suitable for the Thai Population - A Pilot Study.

Background: Patient self-assessment is a potential tool in clinical practice to obtain subjective information of acne severity also in clinical trials to assess the general population in research and epidemiologic studies. The patient self-evaluation of acne severity has not yet been developed in Thailand.

Objective: We aimed to validate an acne severity grading self-assessment suitable for the Thai population.

Granulomatous Pigmented Purpuric Dermatosis in a Patient with (Inactive) Myasthenia Gravis: A Case Report and Review of the Literature.

Granulomatous pigmented purpuric dermatosis (GPPD) is a rare histologic variant of pigmented purpuric dermatosis (PPD) characterized by dermal histiocyte-rich interstitial infiltration with or without granuloma formation in addition to the other typical features of PPD. GPPD was previously observed more frequently to affect Asians and was reported to be associated with dyslipidemia. However, our literature search of 45 documented GPPD cases revealed an increasing prevalence in Caucasians in addition to dyslipidemia and associated autoimmune diseases.

Algorithm for Correction of Unaesthetic High Eyelid Folds.

Background: Unaesthetic high eyelid fold is a challenging problem for plastic surgeons. Several methods have been introduced to overcome different deformities. Decision-making on how to select the most appropriate procedure for each patient with diverse underlying causes requires ample surgical experience.

A Randomized, Double-Blind, Split-Face Study of Topical Silymarin vs 2% Hydroquinone Cream in Melasmas.

Background: Hydroquinone is effective in melasma treatment, but side effects may limit its use. Silymarin cream may be a safer alternative.

Objective: To compare the efficacy of 1.

Effectiveness of an epidermal growth factor-containing cream on postinflammatory hyperpigmentation after 1064-nm Q-switched neodymium-doped yttrium aluminum garnet laser treatment of acquired bilateral nevus of Ota-like macules (Hori's nevus) in Asians: A split-face, double-blinded, randomized controlled study.

Background: Epidermal growth factor (EGF) may promote wound healing and decrease laser-induced postinflammatory hyperpigmentation (PIH).

Objectives: To evaluate the effectiveness of an EGF-containing cream on PIH, post-laser erythema, and transepidermal water loss (TEWL) after 1,064-nm Q-Switched Nd: YAG laser treatment of Hori's nevus.

Methods: This is a split-face, double-blinded, randomized, controlled study conducted in 30 subjects with bilateral Hori's nevus.

The efficacy and safety of a combined multipolar radiofrequency with pulsed electromagnetic field technology for the treatment of vaginal laxity: a double-blinded, randomized, sham-controlled trial.

Non-invasive vaginal rejuvenation with radiofrequency (RF) and lasers devices have gained popularity, but well-designed studies confirming their effectiveness are lacking. The aim of this study was to compare the efficacy and safety of a multipolar RF and pulsed electromagnetic field-based device (PEMF) versus sham for vaginal laxity. Thirty-two premenopausal females with ≥ 1 vaginal delivery and self-reported vaginal laxity were randomized into 2 groups: active (RF + PEMF) and sham.

Mesh Suspension Thread for Facial Rejuvenation.

Background: Thread lifting was first described in the early twentieth century, but for many years it remained a relatively debatable technique due to the unreliability of the long-term results. Very few papers described the long-term follow-up of the patients. Until now there has been no ideal thread that can demonstrate the long-lasting results.

Bullous Pemphigoid Associated with Acquired Hemophilia A: A Case Report and Review of the Literature.

Acquired hemophilia A (AHA) is a rare autoimmune disorder with high morbidity and mortality. It results from the development of circulating autoantibodies against factor VIII. AHA can be seen in association with autoimmune vesiculobullous diseases, autoimmune diseases, malignancy, pregnancy, and medications.

Serum Sickness after Equine Rabies Immunoglobulin in Identical Male Twins: Two Case Reports.

We, hereby, report two cases of serum sickness in adult male identical twins who had received equine rabies immunoglobulin as a postexposure rabies treatment after cat scratches. The younger brother developed low-grade fever, polyarthritis, and multiple erythematous maculopapular eruptions, whereas low-grade fever and urticaria-like eruptions were detected in the elder brother. Both patients received a 7-day course of low-dose prednisolone and achieved good responses without recurrent attacks.

Thyroid Autoimmunity and Autoimmunity in Chronic Spontaneous Urticaria Linked to Disease Severity, Therapeutic Response, and Time to Remission in Patients with Chronic Spontaneous Urticaria.

Background: Chronic spontaneous urticaria (CSU) is autoimmune in nature and associated with thyroid autoimmunity (TA), but evidence on autoimmunity in relation to CSU progression and prognosis is limited. We evaluated whether TA and autoimmunity in CSU are correlated with disease severity, therapeutic response, and time to remission and establish an association between CSU characteristics linked to thyroid autoantibody.

Methods: Medical records of patients diagnosed with urticaria attending outpatient dermatology clinic at a university-based hospital from 2013 to 2017 were retrospectively reviewed.

The study of histological changes of the arterial vascular structure after hyaluronidase exposure.

Background: Hyaluronic acid (HA) filler injection is commonly used for soft tissue augmentation. Uncommon but serious complication from filler injection is vascular occlusion. Hyaluronidase enzyme can be used to dissolve HA filler.

Prevalence of polycystic ovary syndrome in Thai University adolescents.

Polycystic ovarian syndrome (PCOS) is a common and complex condition characterized by endocrine features and influenced by genetic and environmental factors. In Southeast Asia and Thailand, the prevalence of PCOS is unknown. The aim of this study was to estimate the prevalence of and determine factors associated with PCOS in Thai adolescents.

Dapsone-induced severe cutaneous adverse drug reactions are strongly linked with HLA-B*13: 01 allele in the Thai population.

Objectives: A previous publication in Chinese leprosy patients showed that the HLA-B*13:01 allele is a strong genetic marker for dapsone-induced drug hypersensitivity reactions, however there are no data describing whether HLA-B*13:01 is a valid marker for prediction of dapsone-induced drug hypersensitivity reactions in other ethnicities or nonleprosy patients. The aim of this study is to investigate whether there is an association between HLA genotypes and dapsone-induced severe cutaneous adverse reactions (SCARs) in Thai nonleprosy patients.

Patients And Methods: HLA-B genotypes of 15 patients with dapsone-induced SCARs (11 drug reaction with eosinophilia and systemic symptoms, 4 Stevens-Johnson syndrome/toxic epidermal necrolysis), 29 control patients, and 986 subjects from the general Thai population were determined by the reverse PCR sequence-specific oligonucleotides probe.

Nevirapine patch testing in Thai human immunodeficiency virus infected patients with nevirapine drug hypersensitivity.

Background: Antiretroviral drug hypersensitivity in HIV patients is common. Publications have shown that Abacavir (ABC) patch testing is useful in confirming ABC hypersensitivity in 24-50% of cases with a 100% sensitivity of HLA-B*5701 in patch test positive cases. However, Nevirapine (NVP) patch testing has not been reported.

Secondary Blepharoplasty: Correction of the High Fold.

Background: Blepharoplasty is a common aesthetic surgery performed worldwide. In Asians, too high eyelid folds after blepharoplasty cause an unsatisfactory aesthetic outcome that is difficult to correct. In this article, the authors propose surgical techniques to correct the high eyelid fold after blepharoplasty.

A Novel Technique of Supra Superficial Musculoaponeurotic System Hyaluronic Acid Injection for Lower Face Lifting.

Background: Various methods attempting to correct sagging of the lower face focus mainly on manipulation of the superficial musculoaponeurotic System. Each technique has its own limitation. The authors propose a relatively simple, conservative method utilizing hyaluronic acid injection just above the superficial musculoaponeurotic System.

The periosteal pulley technique for orbital fat realignment and correction of nasojugal groove in lower lid blepharoplasty.

Background: Removal of orbital fat in lower lid blepharoplasty has been widely replaced by fat realignment over the orbital rim. However, incomplete correction or recurrence of fat bulging is still common compared to a simple fat removal procedure due to improper transfer and fixation of fat over the orbital rim. The authors present a novel technique of orbital fat transfer under the periosteal strip to secure the fat along the orbital rim and prevent recurrence of fat bulging from reherniation.

Effectiveness of onion extract gel on surgical scars in asians.

Background. Onion extracts have been shown in vitro to accelerate wound healing. Results from clinical studies on surgical scars in Caucasians were disappointing.

Periorbital rejuvenation with fractional 1,550-nm ytterbium/erbium fiber laser and variable square pulse 2,940-nm erbium:YAG laser in Asians: a comparison study.

Background: Ablative and fractional lasers are used for periorbital rejuvenation, with different downtime, side effects, and efficacy.

Objectives: To compare effects of fractional 1,550-nm ytterbium- and erbium-doped (Yb/Er) fiber laser and variable square pulse (VSP) 2,940-nm erbium-doped yttrium aluminum garnet (Er:YAG) laser treatment for periorbital wrinkles.

Materials And Methods: This side-by-side comparison study randomized 22 women with mild to moderate periorbital rhytides to receive three treatments with fractional 1,550-nm Yb/Er fiber laser or 2,940-nm Er:YAG laser treatment on either side at 4-week intervals.

Side effects and complications of fractional 1550-nm erbium fiber laser treatment among Asians.

Background:   Fractional erbium fiber laser is an effective treatment for facial wrinkles, acne scars, and dyspigmentation available worldwide. However, there are minimal data of adverse events and complications in Asians.

Objective:   To determine safety and adverse events associated with fractional erbium laser treatment in Asian patients.