Publications by authors named "Watcharamon Prasert"
A Biochemical and Pharmacological Characterization of Phospholipase A and Metalloproteinase Fractions from Eastern Russell's Viper () Venom: Two Major Components Associated with Acute Kidney Injury.
Janeyuth Chaisakul Orawan Khow Kulachet Wiwatwarayos Muhamad Rusdi Ahmad Rusmili Watcharamon Prasert
Toxins (Basel)
July 2021
Article Synopsis
- Acute kidney injury (AKI) is a major symptom in victims of Eastern Russell's viper envenoming, largely due to specific venom components that cause nephrotoxicity.
- The study identified two purified proteins, RvPLA (snake venom phospholipase A) and RvMP (a factor X activator), which were linked to harmful effects on organs including the kidneys, heart, and spleen.
- Findings suggest that RvPLA and RvMP contribute significantly to AKI and related symptoms in envenomed victims, highlighting the need for updated treatment strategies to address their potential irreversible nephrotoxicity.