Evaluation of a therapeutic carbon beam using a G2000 glass scintillator.

A G2000 glass scintillator (G2000-SC) was used to determine the carbon profile and range of a 290-MeV/n carbon beam used in heavy-ion therapy because it was sensitive enough to detect single-ion hits at hundreds of mega electron Volts. An electron-multiplying charge-coupled device camera was used to detect the ion luminescence generated during the irradiation of G2000-SC with the beam. The resulting image showed that the position of the Bragg peak can be determined.

Development of the Dual-Beam Ion Irradiation Facility for Fusion Materials (DiFU).

The Dual-beam ion irradiation facility for Fusion materials (DiFU) has been developed and installed at the Ruđer Bošković Institute with the purpose to perform irradiation of samples of fusion materials by one or two ion beams. Ion beams are delivered to the DiFU chamber by a 6 MV EN Tandem Van de Graaff and a 1 MV HVE Tandetron accelerator, enabling irradiation of areas up to 30 × 30 mm. The sample holder enables the three-dimensional positioning of samples that can be irradiated while being heated, cooled, or kept at room temperature.

All-Optical Wide-Field Selective Imaging of Fluorescent Nanodiamonds in Cells, and .

Fluorescence imaging is a critical tool to understand the spatial distribution of biomacromolecules in cells and , providing information on molecular dynamics and interactions. Numerous valuable insights into biological systems have been provided by the specific detection of various molecular species. However, molecule-selective detection is often hampered by background fluorescence, such as cell autofluorescence and fluorescence leakage from molecules stained by other dyes.

Optimization of Wide-Field ODMR Measurements Using Fluorescent Nanodiamonds to Improve Temperature Determination Accuracy.

Fluorescent nanodiamonds containing nitrogen-vacancy centers have attracted attention as nanoprobes for temperature measurements in microenvironments, potentially enabling the measurement of intracellular temperature distributions and temporal changes. However, to date, the time resolution and accuracy of the temperature determinations using fluorescent nanodiamonds have been insufficient for wide-field fluorescence imaging. Here, we describe a method for highly accurate wide-field temperature imaging using fluorescent nanodiamonds for optically detected magnetic resonance (ODMR) measurements.

Triple nitrogen-vacancy centre fabrication by CNH ion implantation.

Quantum information processing requires quantum registers based on coherently interacting quantum bits. The dipolar couplings between nitrogen vacancy (NV) centres with nanometre separation makes them a potential platform for room-temperature quantum registers. The fabrication of quantum registers that consist of NV centre arrays has not advanced beyond NV pairs for several years.

Annihilation gamma imaging for carbon ion beam range monitoring using Si/CdTe Compton camera.

In this study, we performed on-beam monitoring of 511 keV annihilation gamma emissions using a Compton camera. Beam monitoring experiments were conducted using carbon ion beams of 290 MeV/u irradiated on a polymethyl methacrylate (PMMA) phantom. The intensity of the beams was 3  ×  10 particles per pulse, with 20 pulses per minute.

Visualization of focused proton beam dose distribution by atomic force microscopy using blended polymer films based on polyacrylic acid.

A simple and sensitive sub-micrometer scale method for visualization of the dose distribution of a focused proton beam (FPB) was developed, taking advantage of the formation of a bulky crosslinked structure induced by FPB irradiation of a common polymer and cross-linker, polyacrylic acid-N, N'-methylene bisacrylamide, blend film surface. The irradiated part of the film swelled as a peak, and the height of swelling increased with increasing FPB fluence. The film was used as a proton beam-sensitive polymer film by analysis of the irradiated film surface using atomic force microscopy.