Publications by authors named "Watarai Y"
Background/aim: Sports mouthguard should be designed and fabricated adequately. The purpose was to propose a criterion for fabricating sports laminate mouthguard with adequate thickness for protect orofacial structures.
Materials And Methods: Ethylene vinyl acetate sheet (Sports Mouthguard) was fabricated using a pressure former.
De novo donor-specific antibodies (dnDSA), particularly those against human leukocyte antigen (HLA) class II, can cause kidney allograft rejection, resulting in poor prognosis. Recently, HLA matching at both B-cell and T-cell epitopes, assessed by eplet mismatches and predicted indirectly recognizable HLA epitopes (PIRCHE) score, respectively, has been reported to be associated with dnDSA production. It remains unclear how these epitopes are involved in transplant immunology and how the results of the analysis can be applied in clinical practice.
View Article and Find Full Text PDFPurpose: This study aimed to investigate the relationships between reference planes and oral functions on the habitual and non-habitual chewing sides.
Materials And Methods: Thirty-four subjects with no abnormalities in the maxillofacial region and oral functions were enrolled in this study. Relationships between angles between the reference plane (Frankfort horizontal plane, Camper's plane, and occlusal plane) and masticatory performance, occlusal force, and occlusal contact area by chewing side were examined.
Article Synopsis
- The study investigates pain levels in children under 5 years undergoing inguinal hernia repair using either laparoscopic approach (LA) or traditional open approach (OA).
- A total of 74 patients' records were reviewed, and pain was assessed using the FLACC scoring system, which rates pain based on facial expressions, leg movement, activity, crying, and consolability.
- Results showed that while LA is less invasive, it did not result in lower postoperative pain levels compared to OA, particularly in children younger than 2 years.
Article Synopsis
- The study investigates the risk factors for acute antibody-mediated rejection (ABMR) in ABO blood group incompatible kidney transplants (ABO-I), focusing on donor and recipient samples.
- Researchers analyzed A/B antigen expression in kidney tissues and other blood components from 104 donors and assessed pre-transplant recipient serum samples for antibody levels.
- They found that while A/B antigen levels in donors did not correlate with ABMR incidence, higher C1q-IgG binding ability in recipients was linked to an increased risk of ABMR, suggesting it may serve as a predictive indicator.
Article Synopsis
- The study examined joint effusion in patients with temporomandibular disorders (TMDs) that involved disc displacement, using MRI images of 97 temporomandibular joints (TMJs).
- Of the TMJs evaluated, joint effusion was observed in 70 cases, primarily in the superior articular cavity, and the presence of myofascial or TMJ pain did not affect the occurrence of effusion.
- The findings indicated that joint effusion is more prevalent in cases of disc displacement without reduction and that the volume of synovial fluid in effusions was unaffected by the presence of pain.
Article Synopsis
- In pancreatic transplantation, a new technique addresses challenges of a distended graft duodenum caused by pancreatic juice production after blood flow is restored.
- The method involves leaving the anal side of the graft duodenum uncut initially to allow drainage, which helps in managing bleeding and ensures better conditions for anastomosis to the recipient's small intestine.
- By using this drainage technique, surgeons can focus on critical tasks like hemostasis and avoid complications associated with inadequate blood flow to the graft.
Tertiary hyperparathyroidism (THPT) is characterized by elevated parathyroid hormone and serum calcium levels after kidney transplantation (KTx). To ascertain whether pre-transplant calcimimetic use and dose information would improve THPT prediction accuracy, this retrospective cohort study evaluated patients who underwent KTx between 2010 and 2022. The primary outcome was the development of clinically relevant THPT.
View Article and Find Full Text PDFIntroduction: Kidney transplantation (KT) involving elderly living kidney donors (LKDs) is becoming more frequent because of a profound organ shortage. The efficacy of KT involving grafts obtained from LKDs aged 70 years or older has been reported. However, the safety of donor nephrectomy in LKDs aged 70 years or older, including that associated with changes in the estimated glomerular filtration rate (eGFR), has not been investigated.
View Article and Find Full Text PDFPurpose: To investigate the clinical characteristics of lung cancer that develops after kidney transplantation.
Methods: The clinical data of patients with lung cancer diagnosed after kidney transplantation were collected retrospectively. The medical records were extracted from our database.
Introduction: The impact of the perioperative estimated glomerular filtration rate (eGFR) on graft survival in kidney transplant recipients is yet to be evaluated. In this study, we developed prediction models for the ideal perioperative eGFRs in recipients.
Methods: We evaluated the impact of perioperative predicted ideal and actual eGFRs on graft survival by including 1,174 consecutive adult patients who underwent living-donor kidney transplantation (LDKT) between January 2008 and December 2020.
Article Synopsis
- * Out of 17 participants, TMA symptoms appeared within 72 hours post-transplant, with 16 cases involving ABO incompatibility, and the usage of pre-transplant plasmapheresis was found to be low.
- * Although some gene variants related to TMA were identified in Japanese and East Asian patients, most cases did not lead to significant complications, suggesting that further research is needed to fully understand the genetic risks associated with dnTMA post-KTx.
Introduction: Following total parathyroidectomy (PTx), transcervical thymectomy, and forearm autograft for secondary hyperparathyroidism (SHPT), recurrent SHPT can occur in the autografted forearm. However, few studies have investigated the factors contributing to re-PTx due to autograft-dependent recurrent SHPT before the completion of the initial PTx.
Methods: A total of 770 patients who had autografted parathyroid fragments derived from only one of the resected parathyroid glands (PTGs) and who had undergone successful initial total PTx and transcervical thymectomy-defined by serum intact parathyroid hormone level < 60 pg/mL on postoperative day 1-between January 2001 and December 2022 were included in this retrospective cohort study.
Background: Long-term dialysis vintage is a predictor of persistent hyperparathyroidism (HPT) after kidney transplantation (KTx). Recently, preemptive kidney transplantation (PKT) has increased. However, the incidence, predictors, and clinical implications of HPT after PKT are unclear.
View Article and Find Full Text PDFBackground: This study investigated the factors involving joint effusion in patients with temporomandibular disorders.
Methods: The magnetic resonance images of 131 temporomandibular joints (TMJs) of patients with temporomandibular disorders were evaluated. Gender, age, disease classification, duration of manifestation, muscle pain, TMJ pain, jaw opening disturbance, disc displacement with and without reduction, deformation of the articular disc, deformation of bone, and joint effusion were investigated.
Treatment for secondary hyperparathyroidism focusing on parathyroidectomy.
Front Endocrinol (Lausanne)
May 2023
Secondary hyperparathyroidism (SHPT) is a major problem for patients with chronic kidney disease and can cause many complications, including osteodystrophy, fractures, and cardiovascular diseases. Treatment for SHPT has changed radically with the advent of calcimimetics; however, parathyroidectomy (PTx) remains one of the most important treatments. For successful PTx, removing all parathyroid glands (PTGs) without complications is essential to prevent persistent or recurrent SHPT.
View Article and Find Full Text PDFExamination of facial measurement on the image using a noncontact three-dimensional measurement device.
J Family Med Prim Care
December 2022
Background: Producing dentures for edentulous patients is important to improve quality of life of elderly. The determination of the occlusal vertical dimension on producing dentures is one of the key factors for using the dentures comfortably. The purpose of this study is to consider the usefulness of the determination of the occlusal vertical dimension of a facial measurement method applied on scanned facial image using a noncontact three-dimensional measurement device.
View Article and Find Full Text PDFArticle Synopsis
- GLP-1 receptor agonists (RAs) may help improve kidney function in patients after kidney transplantation, particularly for those with type 2 diabetes.
- This study analyzed data from kidney transplant recipients to see if GLP-1 RAs reduced the risk of significant kidney function decline (measured by eGFR) compared to other diabetes medications.
- Results showed that those using GLP-1 RAs had a significantly lower risk of sustained eGFR reduction, suggesting these medications could enhance kidney graft survival post-transplant.
Background: The comparative impact of everolimus (EVR)-based regimens versus standard of care (mycophenolic acid+standard calcineurin inhibitor [MPA+sCNI]) on cardiovascular outcomes in de novo kidney transplant recipients (KTRs) is poorly understood. The incidence of major adverse cardiac events (MACEs) in KTRs receiving EVR+reduced CNI (rCNI) or MPA+sCNI from the TRANSplant eFficacy and safety Outcomes with an eveRolimus-based regiMen study was evaluated.
Methods: The incidence of MACE was determined for all randomized patients receiving at least 1 dose of the study drug.
Light chain deposition disease (LCDD) is a rare manifestation of monoclonal gammopathy, which can lead to renal failure. We previously reported a detailed recurrence process in a case of LCDD after renal transplantation. To the best of our knowledge, no report has described the long-term clinical course and renal pathology findings of recurrent LCDD in patients after renal transplantation.
View Article and Find Full Text PDFBackground: The clinical outcomes of ABO-incompatible (ABOi) kidney transplantation have improved with the introduction of desensitization therapy with rituximab. However, rituximab prevents not only antibody-mediated rejection (AMR) but also increases the risk of adverse events, such as infection. For ABOi kidney transplantation in patients with low anti-A/B antibody titers, we previously used a rituximab-free desensitization protocol and then initiated a single dose of 100 mg rituximab in 2016.
View Article and Find Full Text PDFBackground/aim: Polyolefin sheets are fabricated in the same manner as ethylene vinyl acetate sheets. The aim of this study was to examine the difference of vacuum-formed mouthguard thickness according to each heating condition using ethylene vinyl acetate and polyolefin sheets.
Materials And Methods: Mouthguard sheets of 3.
Article Synopsis
- Total parathyroidectomy (PTx) is a surgery done to help people with a condition called secondary hyperparathyroidism (SHPT), especially those with kidney disease.
- A study looked at 344 patients to find out what factors help make this surgery successful before it's even finished.
- Results showed that finding more parathyroid glands during the surgery and seeing a big drop in certain hormone levels were important for making sure the surgery worked well.