Urinary tract infections in patients with multiple sclerosis and different methods of bladder evacuation.

Introduction And Objectives: To evaluate the incidence and course of urinary tract infections (UTI) in patients with multiple sclerosis (MS) and their relationship to the method of bladder evacuation.

Materials And Methods: Patients with neurogenic bladder dysfunction due to MS (n=111) were enrolled in the study. During one-year follow-up, clinical examination with urine culture was performed every 4 months or whenever symptoms occurred.

Short-term Outcomes of Water Vapor Therapy (Rezūm) for BPH/LUTS in the First Czech Cohort.

Purpose: To evaluate the short-term results of water vapor therapy (Rezūm) for BPH/LUTS in the first cohort of Czech patients.

Materials And Methods: Patients with BPH and moderate to severe LUTS (N = 76) who underwent Rezūm treatment from December 2019 to July 2020 were included in the prospective study. Prior to the procedure, they completed the IPSS and OABv8 questionnaires and underwent uroflowmetry, transrectal ultrasound of the prostate, and PSA sampling.

MicroRNAs in the pathogenesis of renal cell carcinoma and their diagnostic and prognostic utility as cancer biomarkers.

Purpose: To provide information about the role of microRNAs in the pathogenesis of renal cell carcinoma (RCC) and their diagnostic and prognostic utility as cancer biomarkers.

Methods: A literature search was performed in the PubMed and Web of Science databases using the keywords "renal cancer/renal cell carcinoma/kidney cancer" and "miR*/miRNA*/microRNA*". Articles dealing with the role of miRNAs in the pathogenesis of RCC, diagnostic miRNAs and prognostic miRNAs were separated.

Mast cell stabilization with sodium cromoglycate modulates pulmonary vessel wall remodeling during four-day hypoxia in rats.

Aim Of The Study: In rats, the environment with low content of oxygen induces hypoxic pulmonary hypertension. Remodeling of pulmonary resistance arteries is particularly triggered by the mast cell degranulation products, e.g.

[Biodegradation of silicone in voice prosthesis].

The most important problem of the useful life of vocal prostheses is bacterial and especially mycotic colonization of their surface which impaired tightness of the closing valve of the prosthesis and caused subsequent leakage of fluids and food into the airways. The objective of the present study was to prevent colonization of the silicone surface and to prolong the service life of the prosthesis. The implanted prostheses were examined under microscope after varying intervals in vivo.

Effect of cytochrome P-450 inhibition and stimulation on intensity of polyethylene degradation in microsomal fraction of mouse and rat livers.

Polyethylene (PE) is degraded in microsomal fractions of mouse and rat livers with the formation of carbonyl groups. Infrared spectroscopy demonstrated formation of predominantly ketone groups and to a lesser degree ester and aldehyde groups. The inhibition and stimulation of cytochrome P-450 in mouse livers affected the formation of oxidative groups on PE.

Biodegradation of polyethylene foils by bacterial and liver homogenates.

The evaluation of structural changes of single linear and bifurcated polyethylene foils exposed to bacterial and liver homogenates was carried out by infrared spectrography, along with observations of changes of mechanical properties. Cell homogenates were fractionated by centrifugation and by coagulating the microsomal fraction using Ca2+ ions. Stimulation as well as inhibition of the presumed enzyme system were studied in bacterial cultures and liver homogenates of experiment animals.