Toxicological evaluation of hydroethanol leaf extract of (Linn.) Juss. (Amaranthaceae) in rodents.

Objectives: Several studies have established the ethnobotanical benefits of (PL) in laboratory animals without extensive toxicological evaluation of its safety profiles. Thus, an extensive toxicological investigation of sub-chronic oral administration of the hydroethanol leaf extract of in rodents was carried out in this study.

Methods: Different groups of rats were treated orally with the extract (10, 50 and 250 mg/kg) daily for 90 consecutive days.

Toxicological evaluation of hydroethanol leaf extract of (Linn.) Juss. (Amaranthaceae) in rodents.

Objectives: Several studies have established the ethnobotanical benefits of (PL) in laboratory animals without extensive toxicological evaluation of its safety profiles. Thus, an extensive toxicological investigation of sub-chronic oral administration of the hydroethanol leaf extract of in rodents was carried out in this study.

Methods: Different groups of rats were treated orally with the extract (10, 50 and 250 mg/kg) daily for 90 consecutive days.

Effect of gasoline fumes on reproductive function in male albino rats.

The increase in the frequency of exposure to gasoline fumes and the growing incidence of infertility among humans has been a major concern and subject of discussion over the years in Nigeria. We therefore present the reproductive effect of gasoline fumes on inhalation exposure in 40 male albino rats. The rats were randomized into five experimental treatments (T) with eight rats per treatment.

Thyroid stimulating hormone assay as the first line biochemical parameter to determine thyroid gland abnormalities.

Increased cellular catabolic activities observed in hyperthyroid state had been established. This is consequent to excessive hormones secreted by the thyroid gland during this condition. A total of 60 subjects comprising of 45 females mean age 43.