Background: The accuracy of dynamic renal scintigraphy in evaluating the function of hydronephrotic kidneys is controversial. This study sought to investigate the effects of ureteral obstruction on renal function and the role of the protein load test (PLT) in evaluating hydronephrotic kidneys' function.
Methods: A ureteral obstruction model was generated with New Zealand white rabbits.
Objective: To investigate the influence of early bladder imaging (EBI) in experimental rabbits on the quantitative calculation of glomerular filtration rate (GFR) by the Gates method.
Methods: We retrospectively analyzed the data of dynamic renal scintigraphy (DRS) in experimental rabbits. We calculated renal uptake during minutes 1-2 and 2-3 by correcting bladder radioactivity and computed the split GFR by renal uptake.
Background: It is controversial to evaluate the function of hydronephrotic kidneys by renal dynamic imaging (RDI). Our aim was to study the features of renal dynamic imaging (RDI) at different stages after unilateral ureteral obstruction (UUO) and to investigate a method that could be reasonably used to evaluate renal function and predict renal functional recoverability.
Methods: We made UUO models using fifteen adult New Zealand white rabbits and systematically observed the changes in kidney morphology, blood flow, radiotracer distribution and function by RDI.
Background: There is a lack of consensus concerning changes in renal function after unilateral ureteral obstruction. The aim of this study was to assess the influence of ureteral obstruction on renal morphology and function and to explore the effectiveness of dynamic renal scintigraphy in evaluating obstructive renal function.
Methods: We established a model of right ureteral obstruction using New Zealand white rabbits.