Publications by authors named "Warren J Xu"
Ketogenic diet leads to O-GlcNAc modification in the BTBR mouse model of autism.
Biochim Biophys Acta Mol Basis Dis
September 2017
Article Synopsis
- The study investigates how a ketogenic diet (KD) affects O-linked-β-N-acetyl glucosamine (O-GlcNAc) patterns in a mouse model of autism spectrum disorder (BTBR).
- The KD decreased global O-GlcNAc levels in the liver but did not change levels in the brain, suggesting tissue-specific effects of the diet.
- Findings indicate that the KD may not confer therapeutic benefits in the BTBR model through O-GlcNAc pathways, as brain O-GlcNAc levels remained stable despite dietary changes.