Publications by authors named "Waqas Naseem"

The Early Cretaceous clay-rich facies of the Sembar Formation represent the most significantly occurring organic-rich sediments in the Southern Indus Basin of Pakistan. In this study, detailed geochemical research of total organic carbon, biomarker, mineralogy and trace elemental compositions, together with kerogen microscopic analysis, were carried out and used to understand the organic matter input and the dispositional environmental setting of the organic-rich Sembar shale. The Sembar shales have high organic matter, as indicated by the total organic carbon (TOC) content of up to 2.

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Oil-bearing sandstone samples were collected from the Lower Cretaceous sequence in the Kharir-2 exploration well, Kharir oilfields (Eastern Yemen). The current study integrates biomarker of the aliphatic hydrocarbon fraction of the extracted oil with a new finding from the molecular structure of the oil-asphaltene, in order to learn more about their properties, including organic matter (OM) input, depositional environment, and thermal maturity. The overall oil composition results show that the extracted oils have a high saturated hydrocarbon of up to 50% and significant levels of aromatic hydrocarbon and polar components, indicating generally paraffinic to naphthenic oil.

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This investigation looks at the Late Triassic Baluti Formation's organic geochemical, mineralogical, and petrographical characteristics from a single exploration well (TT-22) near the Taq Taq oilfield in northern Iraq. The Baluti Formation shale samples that were studied in the studied well have high total organic carbon (TOC %) values up to 4.92 wt % and mostly hydrogen-rich types I and II kerogen with a minor gradient to types II/III and III kerogen, indicating a good oil-source rock.

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The Jiza-Qamar Basin is one of the most important exploration sedimentary basins in Yemen. For over a decade, the exploration of hydrocarbons has been occurring in this basin. Late Cretaceous age rocks are the most occurring organic-rich sediments in this basin, including coals, coaly shales, and shales.

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Article Synopsis
  • DNA polymerases are essential enzymes that replicate genetic information in nucleic acids, ensuring that every living cell can accurately copy its genomic DNA during cell division.
  • Thermostable DNA polymerases are particularly valuable in biotechnology and molecular biology, facilitating techniques like DNA cloning, sequencing, and PCR.
  • Research continues into the discovery and engineering of various DNA polymerases, with ongoing studies aimed at understanding their specialized functions and developing new applications for them.
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  • - Cancer results from genetic mutations and is a leading cause of global mortality. CRISPR/Cas9 is a powerful gene-editing technology originally found in bacteria that shows promise for cancer research and treatment.
  • - CRISPR can advance cancer diagnosis by quickly detecting key genes related to cancer development and growth, and it plays a significant role in immunotherapy following traditional treatments like surgery and chemotherapy.
  • - Despite its potential, CRISPR/Cas9 faces challenges like off-target effects, delivery issues, and low HDR efficiency that require further research to ensure effective clinical application in cancer therapies.
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The current study features PAHs exposure on Karakoram Highway, a route of utmost importance in Pakistan. The drivers of heavy traffic vehicles (HTV) on Karakoram Highway spend long hours amid dense traffic and therefore, inevitably inhale huge amount of PAH carcinogens. The urinary metabolites of PAHs in such drivers (meeting selection criteria n = 48) and a control group (n = 49) were comparatively profiled.

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Article Synopsis
  • Genome-editing technologies like CRISPR/Cas9 allow scientists to modify DNA in organisms to produce valuable biotechnological products, with CRISPR being the most favored tool due to its efficiency and cost-effectiveness.
  • CRISPR has numerous applications across various fields, including agriculture, medicine, and even pandemic response, notably for early detection and treatment of SARS-CoV-2.
  • The review discusses the features of genome-editing tools, highlights CRISPR's structure and broad applications, and touches on the challenges and future possibilities of this technology.
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