SCLEREDEMA DIABETICORUM; A RARE DISEASE.

Scleredema Diabeticorum (SD) is a rare condition characterized by diffuse, symmetrical induration along with non-pitted swelling mostly on the upper back as a result of mucin being deposited in the dermis. It can also involve posterior neck, shoulders, and scalp. We report a case of 48 years old female patient from Pakistan, with uncontrolled diabetes mellites type 2 for the last 15 years, presenting with thickened skin at the back of the neck resulting in difficulty in neck and shoulder movements.

Analyzing the impact of holistic building design on the process of lifecycle management of building structures.

This research examines how Holistic Building Design (HBD) affects Lifecycle Management of Building Structures in the ever-changing construction market. HBD includes adaptability, environmental sustainability, maintenance, and disaster preparation. It is a key idea in the present boom in resilient and sustainable building techniques.

Internet of things (IoT) for safety and efficiency in construction building site operations.

Internet of Things (IoT) technologies present transformative opportunities through connectivity of intelligent devices, environmental sensors, and integrated management systems. This study aims to investigate the benefits and impact of IoT implementation on construction sites by analyzing relationships between key factors and outcomes for safety and efficiency. Hypotheses were developed proposing positive correlations between each factor and effective IoT adoption on construction sites.

Influence of IoT implementation on Resource management in construction.

The desire to increase resource management efficacy in the construction sector is expanding because of measures to reduce costs, boost productivity, and minimize environmental impact. The Internet of Things (IoT) has the potential to alter resource management in the construction sector by delivering real-time data and insights that may assist decision-makers in optimizing resource allocation and usage. Incorporating Internet of Things (IoT) technology into the construction sector will be investigated in this study to discover how resource management is affected.

Optimizing photocatalytic performance with Ag-doped ZnO nanoparticles: Synthesis and characterization.

The development of nanotechnology has significantly impacted the improvement of photocatalytic performance of ZnO NPs. In this study synthesis of pure ZnO and Ag-ZnO nanoparticles via a co-precipitation method at varying Ag concentrations (1 %, 2 %, 3 %, 4 % and 6 %) to enhance their photo catalytic efficacy. X-ray diffraction (XRD) analysis estimates crystallite size which decreased by increasing Ag concentration, ranging from 30.

Deterrents to the IoT for smart buildings and infrastructure development: A partial least square modeling approach.

Implementing Internet of things (IoT) technology in the context of intelligent buildings and infrastructure development has garnered significant attention within the construction sector. Nonetheless, the implementation of IoT could be improved by assessing various barriers. The purpose of this study was to examine the obstacles related to the adaptation of IoT techniques within the construction sector, as well as the effects on the advancement of intelligent building and infrastructure systems.

Uterine artery embolization versus myomectomy: a systematic review and meta-analysis.

Introduction: Uterine fibroids are the commonest benign tumors of the reproductive tract in women of childbearing age. They are usually asymptomatic but can cause menorrhagia. Treatments include myomectomy and uterine artery embolization (UAE).

Modeling of success factors of using PU coats in concrete construction projects.

Polyurea coatings are well recognized for their remarkable protective properties, making them highly appropriate for practical use in the field of concrete building. The use of polyurea coatings in the concrete building business is currently constrained, despite its prevalent application in industrialized nations. The limited use may be ascribed to ambiguities about the determinants of effective implementation in this particular setting, as well as the dearth of extensive study in the realm of new building materials.

Frequently used extraoral maxillofacial prosthetic materials and their longevity - A comprehensive review.

The longevity of an extraoral prosthesis depends on its physical and mechanical properties and user maintenance. Faced with multiple outcome measures, researchers find it difficult to determine the most appropriate extraoral prosthetic material. This comprehensive review evaluates the most used extraoral prosthesis materials and qualitatively assesses their longevity and function.

Impact of ITPA gene polymorphism for predicting anemia and treatment outcome in HCV infected patients taking Sofosbuvir Ribavirin therapy.

Background: Globally, 80 million people are suffering from chronic Hepatitis C virus (HCV) infection. Sofosbuvir ribavirin-based anti-HCV therapy is associated with anemia and other adverse effects. Polymorphisms of Inosine triphosphatase (ITPA) gene may cause functional impairment in the Inosine triphosphate pyrophosphatase enzyme, resulting in enhanced sustained viral response (SVR) and protection from ribavirin-associated anemia in patients on therapy.

High gain differentiator based neuro-adaptive arbitrary order sliding mode control design for MPE of standalone wind power system.

In this paper, we introduce a novel Maximum Power Point Tracking (MPPT) controller for standalone Wind Energy Conversion Systems (WECS) with Permanent Magnet Synchronous Generators (PMSG). The primary novelty of our controller lies in its implementation of an Arbitrary Order Sliding Mode Control (AOSMC) to effectively overcome the challenges caused by the measurement noise in the system. The considered model is transformed into a control-convenient input-output form.

Evaluation of factors causing lateral migration of light non-aqueous phase liquids (LNAPLs) in onshore oil spill accidents.

Contamination of groundwater by harmful substances poses significant risks to both drinking water sources and aquatic ecosystems, making it a critical environmental concern. Most on-land spill events release organic molecules known as light non-aqueous phase liquids (LNAPLs), which then seep into the ground. Due to their low density and organic composition, they tend to float as they reach the water table.

Extreme Hypernatremia due to Dehydration.

Hypernatremia is defined as having a serum sodium concentration exceeding 145 mmol/L (normal range is 136 - 145 mmol/L). When the serum sodium level surpasses 160 mmol/L and 190 mmol/L, it is classified as severe and extreme hypernatremia, respectively. Extreme hypernatremia is an uncommon occurrence and is associated with significant risks of mortality and morbidity.

Applications of AI in oil and gas projects towards sustainable development: a systematic literature review.

Oil and gas construction projects are critical for meeting global demand for fossil fuels, but they also present unique risks and challenges that require innovative construction approaches. Artificial Intelligence (AI) has emerged as a promising technology for tackling these challenges, and this study examines its applications for sustainable development in the oil and gas industry. Using a systematic literature review (SLR), this research evaluates research trends from 2011 to 2022.

Impact of 3D Printing on the Overall Project Success of Residential Construction Projects Using Structural Equation Modelling.

After a decade of research and development, 3D printing is now an established technique in the construction sector, complete with its own set of accepted standards. The use of 3D printing in construction might potentially improve the outcome of the project as a whole. However, traditional strategies are often used in the residential construction industry in Malaysia, which causes serious public safety and health issues along with a negative impact on the environment.

Model predictive control of consensus-based energy management system for DC microgrid.

The increasing deployment and exploitation of distributed renewable energy source (DRES) units and battery energy storage systems (BESS) in DC microgrids lead to a promising research field currently. Individual DRES and BESS controllers can operate as grid-forming (GFM) or grid-feeding (GFE) units independently, depending on the microgrid operational requirements. In standalone mode, at least one controller should operate as a GFM unit.

LUCAS compression device-related severe injuries in a series of patients presenting with outside hospital cardiac arrest.

Unlabelled: This case series presents patients who presented to the hospital with an outside hospital cardiac arrest and were initially resuscitated successfully. All patients suffered fatal traumatic injuries during the resuscitation process with the common variable being the use of mechanical cardiopulmonary resuscitation (CPR) device. The goal of this case series is to describe the limitations and potential fatal side effects of CPR.

Genetic Diversity and Virulence Profiling of Multi-Drug Resistant of Human, Animal, and Environmental Origins.

Rapid urbanization has increased human-animal interaction and consequently enhanced the chances to acquire zoonotic diseases. The current investigation is focused to uncover the genetic diversity of multidrug-resistant strains between different ecologies (i.e.

An Effective Color Image Encryption Based on Henon Map, Tent Chaotic Map, and Orthogonal Matrices.

In the last decade, the communication of images through the internet has increased. Due to the growing demands for data transfer through images, protection of data and safe communication is very important. For this purpose, many encryption techniques have been designed and developed.

Cardioprotective Role of Estrogen in Takotsubo Cardiomyopathy.

Takotsubo cardiomyopathy (TC) is a rare, reversible cause of left ventricular wall motion abnormality (LVWMA) that mimics the presentation of acute myocardial infarction (AMI). TC is usually preceded by an emotional or physical stressor and appears to be more common in postmenopausal women. Various pathophysiological hypotheses of TC have been proposed, but the exact mechanism of action remains elusive.

Association between 17q21 variants and asthma predisposition in Pashtun population from Pakistan.

Objective: Asthma is a heterogeneous and genetically complex respiratory disease, and more than 300 million people are affected worldwide. In this study, frequencies of four SNPs (rs3816470, rs7216389, rs8067378, rs12603332) in chromosome 17q21 region were analyzed and their relationship with the asthma susceptibility, in the Pashtun population of Khyber Pakhtunkhwa province (KPK) of Pakistan were investigated.

Methods: DNA samples from 500 subjects (asthma cases/controls) were genotyped by Sanger sequencing.

Association of left atrial strain by cardiovascular magnetic resonance with recurrence of atrial fibrillation following catheter ablation.

Background: Atrial fibrillation (AF) is a progressive condition, which is characterized by inflammation/fibrosis of left atrial (LA) wall, an increase in the LA size/volumes, and decrease in LA function. We sought to investigate the relationship of anatomical and functional parameters obtained by cardiovascular magnetic resonance (CMR), with AF recurrence in paroxysmal AF (pAF) patients after catheter ablation.

Methods: We studied 80 consecutive pAF patients referred for ablation, between January 2014 and December 2019, who underwent pre- and post-ablation CMR while in sinus rhythm.

Discoidin Domain-Containing Receptor 2 Is Present in Human Atherosclerotic Plaques and Involved in the Expression and Activity of MMP-2.

Discoidin domain-containing receptor 2 (DDR2) has been suggested to be involved in atherosclerotic progression, but its pathological role remains unknown. Using immunochemical staining, we located and compared the expression of DDR2 in the atherosclerotic plaques of humans and various animal models. Then, siRNA was applied to knock down the expression of DDR2 in vascular smooth muscle cells (VSMCs), and the migration, proliferation, and collagen -induced expression of matrix metalloproteinases (MMPs) were evaluated.