Publications by authors named "Wanzee Cho"
Article Synopsis
- CSF1R-related leukoencephalopathy is an autosomal dominant leukodystrophy linked to mutations in the CSF1R gene, and shows different brain changes compared to subcortical ischemic vascular dementia (SIVaD), which is related to small vessel disease.
- In a study, researchers compared white matter hyperintensity (WMH) patterns and cortical thickness in 14 patients with CSF1R-related leukoencephalopathy and 129 with SIVaD, using advanced imaging techniques.
- Results indicated that CSF1R-related leukoencephalopathy had more severe corpus callosum atrophy and cortical thinning, with WMH mainly in the frontal and parietal
Multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) are autoimmune inflammatory disorders of the central nervous system (CNS) with similar characteristics. The differential diagnosis between MS and NMOSD is critical for initiating early effective therapy. In this study, we developed a deep learning model to differentiate between multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) using brain magnetic resonance imaging (MRI) data.
View Article and Find Full Text PDFAlthough fatigue is a major symptom in patients with neuromyelitis optica spectrum disorder (NMOSD), the underlying mechanism remains unclear. We explored the relationship between subcortical structures and fatigue severity to identify neural substrates of fatigue in NMOSD. Clinical characteristics with brain magnetic resonance imaging were evaluated in forty patients with NMOSD.
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