Preparation and Flame-Retardant Mechanism of MgAlZn-Based Hydrotalcite-like Coal Spontaneous Combustion Inhibitor.

In this work, the coprecipitation approach was successfully used to create Mg-Al hydrotalcite-like inhibitors modified with varying amounts of Zn, and their characteristics were assessed. The findings indicate that the flame retardancy of Mg-Al hydrotalcite (MgAl-LDHs) is not significantly affected by Zn content. By adding MgAl-LDHs, the temperature at which the exothermic reaction started to occur was raised from 146.

ZhenQi FuZheng formula inhibits the growth of colorectal tumors by modulating intestinal microflora-mediated immune function.

Zhenqi Fuzheng formula (ZQFZ), of which the main ingredients are and , has immune system regulatory functions and potential anti-tumor bioactivity. The inhibition of colorectal tumor growth by ZQFZ was analyzed in inflammatory cells and B6/JGpt-/Gpt () mice. ZQFZ exhibited anti-inflammatory activity by decreasing the phosphorylation of nuclear factor-kappa B (NF-κB) pathway-related proteins in lipopolysaccharide-induced RAW264.

Protection against ulcerative colitis and colorectal cancer by evodiamine via anti‑inflammatory effects.

Evodiamine (Evo) is an alkaloid that can be extracted from the berry fruit and has been reported to exert various pharmacological effects, such as antidiarrheal, antiemetic and antiulcer effects. , the potential effects of Evo were investigated in a mouse model of dextran sodium sulfate (DSS)‑induced ulcerative colitis (UC) and in adenomatous polyposis coli (Apc)/Gpt C57BL/6 mice with colorectal cancer (CRC), where the latter harbours a point‑mutation in the gene. Evo suppressed the degree of weight loss and colon shortening induced by DSS, decreased the disease activity index value and ameliorated the pathological alterations in the colon of mice with UC as examined via H&E staining of colon tissues.