Publications by authors named "Wanying Gao"
Background: Tick-borne infectious diseases caused by the spotted fever group Rickettsia (SFGR) have continuously emerging, with many previously unidentified SFGR species reported. The prevalence of SFGRs in northwestern China remains unclear. This study aimed to examine the prevalence of SFGRs and Anaplasma species by analyzing tick samples collected from the Ningxia region.
View Article and Find Full Text PDFArticle Synopsis
- Ticks are significant carriers of diseases that can affect both humans and animals, posing a growing health risk.
- In a field survey conducted in the Ningxia Hui Autonomous Region of China, researchers collected over 10,000 ticks from nine different species, noting how environmental factors influenced their distribution.
- The findings indicate specific areas in Ningxia are more suitable for certain tick species, highlighting the importance of these results for managing tick populations and controlling tick-borne illnesses, while also suggesting that future studies should explore how reforestation efforts impact tick dynamics.
Article Synopsis
- Scientists discovered new viruses called Restviruses in the lungs of patients who were sick with a type of coronavirus.
- These Restviruses are similar to another group of viruses known as Statoviruses, which were found in the stomachs of animals.
- Researchers think that studying these new viruses could help us understand how they affect people's health and where they come from.
The history of virology, which is marked by transformative breakthroughs, spans microbiology, biochemistry, genetics, and molecular biology. From the development of Jenner's smallpox vaccine in 1796 to 20th-century innovations such as ultrafiltration and electron microscopy, the field of virology has undergone significant development. In 1898, Beijerinck laid the conceptual foundation for virology, marking a pivotal moment in the evolution of the discipline.
View Article and Find Full Text PDFArticle Synopsis
- * Researchers obtained the genome from metagenomic sequencing of an infected goat in China, revealing it has the smallest genome of its genus and indicating lower pathogenicity compared to similar species.
- * The study found a high infection rate of 79.3% in goats and noted significant genetic diversity, providing foundational insights for future studies and potential prevention strategies against this pathogen.
Article Synopsis
- Haemaphysalis longicornis, a type of tick, is becoming a concern because it's spreading and may carry diseases.
- Researchers studied 136 groups of these ticks and found 508 different RNA viruses, with 22 that no one had seen before.
- The study showed that the genetic differences in the ticks are linked to their environment, which helps us understand how viruses might spread from ticks to animals and people.
The complete mitogenome of (Filippova, 1961) and its phylogenetic status in subgenus (Acari: Argasidae).
Int J Parasitol Parasites Wildl
April 2024
Article Synopsis
- Soft ticks from the Argasidae family act as ectoparasites and are known to spread zoonotic diseases, but there’s limited knowledge about their subgenus in China, primarily focusing on occurrence data and single case reports.
- This study characterizes this tick subgenus through detailed mitochondrial sequencing and morphological analysis of adult specimens from Ningxia Hui Autonomous Regions in North China, aiming to fill knowledge gaps.
- The research produced a complete mitogenome of 14,479 bp, identified 37 genes, and showcased morphological features that differentiate these ticks, providing essential data for accurate species identification in the future.
We recently detected a HKU4-related coronavirus in subgenus Merbecovirus (named pangolin-CoV-HKU4-P251T) from a Malayan pangolin. Here we report isolation and characterization of pangolin-CoV-HKU4-P251T, the genome sequence of which is closest to that of a coronavirus from the greater bamboo bat (Tylonycteris robustula) in Yunnan Province, China, with a 94.3% nucleotide identity.
View Article and Find Full Text PDFArticle Synopsis
- Anaplasma capra is a new tickborne bacteria identified in 2015 in China, impacting both humans and a variety of animals globally.
- Researchers sequenced the genomes of two A. capra strains from infected goats, finding that this species has the smallest genome in its genus.
- The study revealed high prevalence in goats, with the strains showing genetic similarities to those previously found in Asia and highlighting the genetic diversity of A. capra.
Article Synopsis
- A tick-borne protozoan poses a significant veterinary health threat to livestock and wildlife, with a limited number of genome sequences available until now.
- Researchers at Cheeloo College of Medicine sequenced the whole genome of a new strain, named str. Cheeloo, derived from infected goats, revealing it has the smallest genome size and fewer gene variations compared to other known species.
- The findings indicate a high infection rate (81.5%) in goats, highlighting str. Cheeloo's significance in the understanding and control of theileriosis, which has resulted in considerable economic losses in animal husbandry.
Investigation of Spatial Coupling Coordination Development: Identifying Land System States from the Adaptation-Conflict Perspective.
Int J Environ Res Public Health
December 2022
With the advancement of global urbanization, ecosystem conservation and sustainable land development have become major issues. In this context, the uncoordinated and imbalanced development of the land-centered human-environment system requires urgent attention, especially in rust belt cities that pose critical challenges to regional land system sustainability. Therefore, taking Changchun City from 1990 to 2020 as an example, we identified and evaluated the ecosystem service (ES) balance and land use conflict from the perspectives of internal support and external development pressure.
View Article and Find Full Text PDFApplication of medical imaging methods and artificial intelligence in tissue engineering and organ-on-a-chip.
Front Bioeng Biotechnol
September 2022
Organ-on-a-chip (OOC) is a new type of biochip technology. Various types of OOC systems have been developed rapidly in the past decade and found important applications in drug screening and precision medicine. However, due to the complexity in the structure of both the chip-body itself and the engineered-tissue inside, the imaging and analysis of OOC have still been a big challenge for biomedical researchers.
View Article and Find Full Text PDFEstrogen has long been known to possess immune-modulatory effects in diseases, and multiple pathological conditions show great sex disparities. However, the impact of estrogen in infection has not been determined. The present study aimed to investigate the role of estrogen in infection and the molecular mechanism.
View Article and Find Full Text PDFSerotype 4821 (ST-4821) clonal complex (cc4821) strains are divided into two groups (groups I and II) according to the core genome-based phylogenetic analysis. Group I contains the greater number of invasive disease isolates. However, the differences in pathogenicity between the two groups are unclear.
View Article and Find Full Text PDFAlthough serogroup W ST-11 complex (cc11) (W:cc11) Neisseria meningitidis has been widespread in China over the past ten years, its origin and genetic relatedness has not yet been described. In this study, we described the genetic relatedness and discuss the possible origin of Chinese W:cc11 isolates by comparing their genome sequences with those of other cc11 strains globally. Comparative genomic analysis with geo-temporally diverse cc11 isolates showed that the Chinese W:cc11 isolates exclusively formed two closely related subclusters within a distinct sublineage (proposed as the Chinese-strain sublineage) of lineage 11.
View Article and Find Full Text PDF