The Drosha-Independent MicroRNA6778-5p/GSK3 Axis Mediates the Proliferation of Gastric Cancer Cells.

Background: Gastric cancer (GC) is a primary cause of cancer death around the world. Previous studies have found that Drosha plays a significant role in the development of tumor cells. Soon after, we unexpectedly found that the expression of microRNA6778-5p (miR6778-5p) is unconventionally high in the gastric cancer cells low-expressing Drosha.

Solvent-Free Procedure to Prepare Ion Liquid-Immobilized Gel Polymer Electrolytes Containing LiLaTiO with High Performance for Lithium-Ion Batteries.

Based on the advantages of intrinsic safety, flexibility, and good interfacial contact with electrodes, a gel polymer electrolyte (GPE) is a promising electrolyte for lithium-ion batteries, compared with the conventional liquid electrolyte. However, the unstable electrochemical performance and the liquid state in a microscale limit the commercial application of GPE. Herein, we developed a novel gel polymer electrolyte for lithium-ion batteries by blending methyl methacrylate (MMA), -butyl--methyl-piperidinium (PyrTFSI), and lithium salts in a solvent-free procedure, with SiO and LiLaTiO (LLTO) additives.

Hydrothermal Synthesis of the CuWO/ZnO Composites with Enhanced Photocatalytic Performance.

Photocatalytic technology aiming to eliminate organic pollutants in water has been rapidly developed. In this work, we successfully synthesized CuWO/ZnO photocatalysts with different weight ratios of CuWO through facile hydrothermal treatment. Crystal structures, forms, and optical properties of these as-prepared materials were investigated and analyzed.

Influence of the substituents on phenyl groups on enantioseparation property of amylose phenylcarbamates.

A series of amylose phenylcarbamate derivatives bearing different chloro- or/and methyl- substituents on the phenyl groups were synthesized and their enantioseparation properties were examined by high-performance liquid chromatography. The enantioseparation power considerably altered due to the substituents on the phenyl units. The amylose derivative bearing 3-chloro-5-methyl disubstituents seemed to possess much higher chiral resolution power.

Chiral recognition ability of amylose derivatives bearing regioselectively different carbamate pendants at 2,3- and 6-positions.

Seven amylose derivatives bearing two regioselective carbamate pendants at 2,3- and 6-positions of a glucose unit were synthesized through protection and deprotection at the 6-position. The chiral recognition abilities of the obtained derivatives were evaluated as the chiral stationary phases (CSPs) for high-performance liquid chromatography (HPLC). Each derivative had its own characteristic recognition ability depending on the arrangement of carbamate pendants at the three positions.

Synthesis of cellulose carbamates bearing regioselective substituents at 2,3- and 6-positions for efficient chromatographic enantioseparation.

Nine cellulose derivatives bearing two different carbamate substituents at 2,3- and 6-positions of a glucose unit were synthesized by a sequential process based on the regioselective protection at 6-position. Their chiral recognition abilities were then evaluated as the chiral stationary phases (CSPs) for high-performance liquid chromatography (HPLC) after coating them onto the macroporous silica gel. The introduction of two different phenylcarbamates at 2,3- and 6-positions of glucose unit was comparatively more attractive than that of one phenylcarbamate and one cyclohexylcarbamate to enhance the chiral recognition ability of these cellulose derivatives.