Publications by authors named "Wanyin Cai"

Background: Researches have found that alteration of intestinal flora may be closely related to the development of autism spectrum disorder (ASD). However, whether probiotics supplementation has a protective effect on ASD remains controversial. This meta-analysis aimed to analyze the outcome of probiotics in the treatment of ASD children.

View Article and Find Full Text PDF
Article Synopsis
  • The study explored trends in hypertension prevalence, awareness, treatment, and control among US adults between 1999 and 2018, revealing an increase in hypertension prevalence from 33.53% to 40.58%.
  • Although the rate of new hypertension diagnoses decreased until 2014 and then slightly increased, awareness and treatment rates remained low, with only about 60% awareness and 51% control by 2018.
  • Key factors influencing hypertension outcomes included gender, income, education, and marital status, suggesting a need for targeted screening and prevention strategies for high-risk groups to improve health management.
View Article and Find Full Text PDF

Objective: Studies on extracorporeal membrane oxygenation (ECMO) with and without an intra-aortic balloon pump (IABP) for cardiogenic shock (CS) have been published, but there have been no meta-analyses that compare the efficacy of these two cardiac support methods. This meta-analysis evaluated the outcomes of these two different treatment measures.

Methods: The PubMed, Embase, Cochrane Library, Web of Science, and Clinical Trials databases were searched until March 2022.

View Article and Find Full Text PDF

Background And Aims: The process of endothelial repair in diabetic patients after stent implantation was significantly delayed compared with that in non-diabetic patients, and oxidative stress is increasingly considered to be relevant to the pathogenesis of diabetic endothelial repair. However, the mechanisms linking diabetes and reendothelialization after vascular injury have not been fully elucidated. The aim of this study was to evaluate the effect of microRNA-24 (miR-24) up-regulation in delayed endothelial repair caused by oxidative stress after balloon injury in diabetic rats.

View Article and Find Full Text PDF

Background And Aims: Neointimal hyperplasia resulting from pathological vascular smooth muscle cells (VSMCs) activation is a common pathophysiological basis for numerous proliferative vascular diseases, such as restenosis. Suv39h1, an important transcription suppressor, may be involved in this process. Herein, we investigated the role of Suv39h1 in pathological intimal hyperplasia and its possible mechanisms in vitro and in vivo.

View Article and Find Full Text PDF

We performed a meta-analysis of randomized controlled trials (RCTs) to investigate the efficacy and safety of ticagrelor (TIC) vs. clopidogrel (CLO) in patients undergoing percutaneous coronary intervention (PCI). In Jun 2016, a literature search was started and all the studies were conducted from 2010 to 2015.

View Article and Find Full Text PDF