Publications by authors named "Wanting Yan"

Introduction: The meniscus is an important cushioning structure of the knee joint, with the maintenance of its normal structure and function playing a crucial role in protecting the joint from early degeneration. Stem/progenitor cells could be the key to help researchers to have a deeper understanding of the biological process of meniscal injury repair and may be important in the meniscus tissue regeneration processes. To the best of our knowledge, there is currently a lack of comprehensive reviews on existing research about the meniscus progenitor cells (MPCs).

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Water is ubiquitous in various heterogeneous catalytic reactions, where it can be easily adsorbed, chemically dissociated, and diffused on catalyst surfaces, inevitably influencing the catalytic process. However, the specific role of water in these reactions remains unclear. In this study, we innovatively propose that HO-driven surface lattice oxygen activation in γ-MnO significantly enhances low-temperature NH-SCR.

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Article Synopsis
  • The study aimed to better understand how medial meniscal posterior root tears heal in goats, focusing on early-stage histologic healing.
  • Eighteen adult goats were divided into three groups to assess different repair techniques after surgery, with evaluations at 12 and 24 weeks for imaging and biomechanical properties.
  • Results showed that the repair method influenced healing quality, with the transosseous suture group showing better outcomes compared to the root tear group, although all samples had weaknesses at the root-meniscus transitions.
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Objective: Meniscus progenitor cells (MPCs) have been identified as promising candidates for meniscus regeneration, and it is crucial for us to understand meniscus injury repair mechanism at the cellular level. In this study, we investigate the biological properties of MPCs isolated from different species using the differential adhesion to fibronectin (DAF) technique. We aim to characterize MPCs in different species and evaluate the feasibility of these models for future meniscal investigation.

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Meniscus is a semilunar wedge-shaped structure with fibrocartilaginous tissue, which plays an essential role in preventing the deterioration and degeneration of articular cartilage. Lesions or degenerations of it can lead to the change of biomechanical properties in the joints, which ultimately accelerate the degeneration of articular cartilage. Even with the manual intervention, lesions in the avascular region are difficult to be healed.

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