Concise Synthesis of Norzoanthamine Enabled by a Set of Photochemical Transformations.

Norzoanthamine is a structurally complex polycyclic natural product that expresses a broad range of biological activities, rendering facile access to it and its analogs of considerable importance in drug discovery and development. However, strategies for efficient access to this class of marine alkaloids remain lacking. Here, we report a strategy, characterized by three key photochemical reactions, that we used to synthesize norzoanthamine in 16 steps.

Trajectory and Determinants of Quality of Life Among Postpartum Women.

Background: The postpartum period is a critical phase in which postpartum women experience dynamic changes in their physiology, psychology, and family status.

Objective: This study investigated the changes in women's quality of life (QoL) during the first, third, and sixth months of the postpartum period and their associated factors.

Methods: A single-group repeated-measure design was used to collect data from 282 postpartum women recruited from a regional hospital in Taiwan.

The mediating effect of pregnancy adaptation between family support and maternal-fetal bonding: a cross-sectional study.

Background: Establishing a nurturing bond with the unborn child is essential for expectant mothers throughout pregnancy. While the influence of family support and pregnancy adaptation on maternal-fetal bonding is evident, these factors remain unexplored in the early stages of pregnancy. This study aims to elucidate the dynamic interaction between family support, pregnancy adaptation, and maternal-fetal bonding during the first trimester, explicitly investigating the mediating role of pregnancy adaptation.

Effect of a Nutritional Education Program on Children's Undernutrition in Indonesia: A Randomized Controlled Trial.

Introduction: To assess effects of a nutritional education program on improving mothers' undernutrition knowledge, self-efficacy, and complementary feeding practices, and reducing undernutrition in children aged <2 years.

Method: A randomized controlled trial was conducted at a community healthcare center in Indonesia. The intervention group participated in a 4-week nutritional education program; the control group received standard care (n = 80; 1:1 ratio).

The Relationships Between Multidimensional Symptom Burden, Adaptation, and Depression During Pregnancy: A Cross-sectional Study.

Prenatal depression is highly prevalent, but its relationship with the multidimensional burden of physical symptoms during pregnancy remains underexplored. The aim of this study was to examine the relationship between pregnancy-related physical symptom burden, including frequency, severity, and impact on life and pregnancy adaptation to prenatal depression, and to identify predictors of depression during pregnancy. The study was cross-sectional in design.

Public policy on breastfeeding among working mothers in Taiwan: comparison between two national surveys.

Background: Creating a supportive breastfeeding environment after childbirth and enabling women to work with reassurance are essential in maternal care services. The study aimed to explore the effectiveness of the utilization rate of public and workplace lactation rooms in relation to the breastfeeding rate among postpartum women returning to work in Taiwan.

Methods: The study involved a secondary data analysis on 6,992 and 7,350 postpartum women surveyed in 2011 and 2016, respectively.

Better safe than sorry: Exploring the collective sensemaking process in pregnancy virtual communities through thematic analysis.

Physical symptoms induced by pregnancy are often perceived as a normal part of the physiological process and therefore not commonly discussed in clinical settings during prenatal care. This study aimed to explore how pregnant individuals adapt to physical symptoms related to their pregnancy, using the perspective of collective sensemaking. A retrospective study design with an inductive thematic analysis approach of qualitative data extracted from web-based forum posts was conducted.

Virtual reality exercise programs ameliorate frailty and fall risks in older adults: A meta-analysis.

Background: Virtual reality (VR) technology constitutes a promising rehabilitation strategy, but its effect on frailty in older adults remains inconclusive. This study examined the effects of interactive VR training programs on lower-limb muscle strength, walking speed, balance, and fall risks in older adults with frailty.

Methods: Various electronic databases comprising PubMed, the Cumulative Index to Nursing and Allied Health Literature, the Cochrane Library, Embase, the Chinese Electronic Periodical Service, the Chinese National Knowledge Infrastructure, and gray literature were searched from their inception through December 31, 2022 for relevant studies.

Using real-time device-based visual feedback in CPR recertification programs: A prospective randomised controlled study.

Background: Receiving regular training to maintain CPR skills is critical for in-service health-care professionals, especially because motor skills diminish over time.

Objectives: To compare the effects of real-time device-based visual feedback and conventional instructor-based feedback on the chest compression skills and self-efficacy of nurses receiving a CPR recertification program.

Design: A prospective randomised controlled study with repeated measurements was conducted according to the CONSORT 2010 guidelines.

Reminiscence music intervention on cognitive, depressive, and behavioral symptoms in older adults with dementia.

This study aimed to examine the efficacy and feasibility of a reminiscence music therapy program on improving cognition and decreasing depressive and behavioral symptoms in older adults with dementia. Participants in the reminiscence music therapy group participated in 60-minute reminiscence music therapy twice a week over a period of 4 weeks. Control group received usual care.

Association of breastfeeding with undernutrition among children under 5 years of age in developing countries: A systematic review and meta-analysis.

Objective: This meta-analysis was conducted to examine the association between breastfeeding and undernutrition among children under 5 years of age in developing countries.

Study Design: Systematic review and meta-analysis.

Methods: A comprehensive literature search was conducted of datasets from Embase, CINHAL, PubMed, Cochrane Library, and Indonesian databases to include eligible studies.

Impact of a peer virtual community on pregnant women's well-being: A repeated-measure and quasi-experimental study.

Aim: To investigate the effects of a virtual community on pregnant women's well-being.

Background: The virtual social network has been growing rapidly but its effects remain unclear.

Design: A repeated-measure and quasi-experimental study.

First-Time Mothers Psychiatric Health Status During the Transition to Motherhood.

The study was conducted to examine the changes of first-time mothers' psychiatric health status, social support, marital intimacy, postpartum stress, and maternal attachment during the transition to motherhood. A repeated measures study was conducted at the 36th week pregnancy, the first week postpartum, and the fourth week postpartum with 217 primiparous women. The results showed that the proportion of women with minor psychiatric morbidity declined over time from late pregnancy to early postpartum.

Depressive symptoms in Taiwanese women during the peri- and post-menopause years: associations with demographic, health, and psychosocial characteristics.

Objective: The purpose of this study was to evaluate the prevalence of depressive symptoms in peri- and post-menopausal Taiwanese women, and to investigate the relation between depressive symptoms and demographic variables, chronic disease status, health habits, stress management, menopausal symptoms, and attitudes toward menopause and aging.

Study Design: Cross-sectional study, using a purposive sample of 566 women between 45 and 60 years of age from a medical center and residential community in Southern Taiwan.

Main Outcome Measures: Demographic and health habits questionnaire, Women's Health Initiative Symptom Scale, Attitudes Toward Menopause and Aging Scale, and Center for Epidemiological Studies-Depression Scale (CES-D).

[Standardized nursing language: the bedrock of computerized nursing records].

Taiwan is currently in the initial phase of implementing a nursing information system. In order to successfully achieve effective communications across dispersed and diverse populations, care settings, and locations, standardized language within the nursing profession must be established and promoted. However, standardized nursing language is not well known among Taiwanese nurses.

A journey of restoring self-confidence: the life experiences of women recipients of augmentation mammaplasty.

The purpose of this qualitative research study was to explore the preoperative through postoperative phase experience of women who had undergone augmentation mammaplasty. Nine women undergoing augmentation mammaplasty were selected by purposive sampling and interviewed using semi- structured, open-ended interview guidelines. Researchers used Symbolic interactionism to frame their overall perspective and analyzed data with the content analysis method.