Synopsis of recent research by authors named "Wanrong Gou"
- Wanrong Gou's recent research focuses on the cytotoxic effects of tetracaine hydrochloride in treating cancer, particularly in melanoma, highlighting its potential to suppress cell proliferation and alleviate drug resistance with mechanisms involving neddylation signaling and key pathways such as lysosome and proteasome signaling.
- Gou's studies have also explored the induction of pyroptosis in macrophages by tetracaine hydrochloride, shedding light on its toxicological impacts and providing insights into its potential therapeutic applications as well as side effects of local anesthetics.
- Additionally, Gou has contributed to the development of a prognostic model based on BRAF mutation-associated genes, aiming to improve prognostic predictions and enhance understanding of the role of BRAF mutations in melanoma progression and patient outcomes.