An industrial structure adjustment model to facilitate high-quality development of an eco-industrial park.

The tradeoff between economic growth and environmental protection has been a critical issue in facilitating eco-industrial park development in China. As the principal contributors to China's industrial output, many industrial parks have been addressing the issues of intensive resource consumption and pollutant generation, driven by much stricter regulations on the environment and resource management. Retuning the industrial structure is a substantial way to address the environmental issues while promoting economic development, which are the goals of eco-industrial development.

Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein.

The Beclin 1 gene is a haplo-insufficient tumor suppressor and plays an essential role in autophagy. However, the molecular mechanism by which Beclin 1 functions remains largely unknown. Here we report the crystal structure of the evolutionarily conserved domain (ECD) of Beclin 1 at 1.

The WD40 repeat PtdIns(3)P-binding protein EPG-6 regulates progression of omegasomes to autophagosomes.

PtdIns(3)P plays critical roles in the autophagy pathway. However, little is known about how PtdIns(3)P effectors act with autophagy proteins in autophagosome formation. Here we identified an essential autophagy gene in C.

C. elegans screen identifies autophagy genes specific to multicellular organisms.

The molecular understanding of autophagy has originated almost exclusively from yeast genetic studies. Little is known about essential autophagy components specific to higher eukaryotes. Here we perform genetic screens in C.