Publications by authors named "Wanqi Ni"
Article Synopsis
- Long-term non-progressors (LTNPs) with HIV can naturally manage the virus for years without treatment, but the reasons behind this ability are still not fully understood.
- The study analyzed blood samples from different groups (LTNPs, untreated viral progressors, treated patients, and healthy individuals) to identify immune factors linked to this natural control of the virus.
- Findings revealed key proteins that distinguish LTNPs from others, suggest potential ways to assess treatment effectiveness, and indicate a network of immune markers that could aid in understanding HIV regulation.
The membrane-proximal external region (MPER) represents a highly conserved region of the Human Immunodeficiency Virus (HIV) envelope glycoprotein (env) targeted by several broadly neutralizing antibodies (bnAbs). In this study, we employed single genome amplification to amplify 34 full-length env sequences from the 2005 plasma sample of CBJC504, a chronic HIV-1 clade B infected individual. We identified three amino acid changes (N671S, D674N, and K677R) in the MPER.
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