Publications by authors named "Wanling Cai"

While microbial technologies, which are considered to be environmentally friendly, have great potential for the recovery of rare earth elements (REEs) from mining wastewater, their applications have been restricted due to a lack of efficient biosorbents. In this study, a strain of Pseudomonas psychrotolerans isolated from yttrium-enriched mine soil was used to recover yttrium (Y(III)) from rare-earth mining wastewater. At an initial Y(III) dose of 50 mg L, the amount of Y(III) adsorbed by P.

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Reduced graphene oxide/iron nanoparticles (rGO/FeNPs) synthesized by the chemical method have been used in Fenton oxidation of organic contaminants, yet little is known about biosynthesized rGO/FeNPs using green tea extract (GT) as how to activate persulfate in sulfate radical-based advanced oxidation processes. In this study, rGO/FeNPs were used to activate peroxydisulfate (PDS) for 17β-estradiol (βE) and estriol (E) removal. The rGO/FeNPs-PDS system removed 83.

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The key step in preparing mesoporous silica is to remove the organic template agent, and the most common method used to achieve this goal is high-temperature calcination. However, this method has many disadvantages, one of which is that it reduces the silanol density on the surface of mesoporous silica, which affects its subsequent modification. Ionic liquids (ILs) are often used as extractants.

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Background: Metabolomics is a tool to study the pathogenesis of diseases and their associated metabolites, but there are still insufficient metabolomic studies on severe knee osteoarthritis.To investigate the differences in serum metabolites between healthy populations and knee osteoarthritis (KOA) patients in Southern China using widely targeted metabolomics, and to explore biomarkers and their metabolic pathways that could be associated with the severity of KOA.

Methods: There were 10 healthy individuals in the control group and 32 patients with KOA.

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Hypertrophic scars (HSs) develop due to excessive collagen deposition and abnormal fibroblast proliferation during wound healing, significantly impacting patient quality of life. Three dosages of GA ointments were administered to rabbit ear HS models to investigate the potential efficacy and mechanism of gallic acid (GA) on HS. Daily application of ointment was performed on the matrix group, the GA ointment groups, and the silicone gel group for 28 days.

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Bio-nanocomposites have attracted increasing research attention because they are able to integrate bio- and nano-related functions, and subsequently demonstrate potentially beneficial environmental applications. Here, a functional bionanomaterial based on Burkholderia cepacian (FZ) immobilized on GO/ZIF-8 was developed and used to remove malachite green (MG), with functions based on both biodegradation and adsorption. XRD and FTIR results showed that in situ production of GO/ZIF-8 by combining Zn in ZIF-8 with the carboxyl group on the GO surface, led to FZ immobilized in GO/ZIF-8 through covalent bonding.

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Ethnopharmacological Relevance: Our previous studies have shown that the Qingre Qushi (QRQS) formula can treat atopic dermatitis (AD), and its possible mechanism is related to the regulation of the IL-33/ST2 signaling pathway. However, the molecular mechanism of AD is complex, and various AD subtypes respond better to therapies aimed at distinct targets.

Aim Of The Study: This study aimed to investigate the multi-target mechanism of QRQS using experimental and network pharmacology studies.

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Metal-organic frameworks (MOFs) have a high specific surface area and inherent biodegradability due to their unique structure and composition. As well, owing to the properties of nanomaterials and especially their magnetic features, FeO nanoparticles and MOFs composite materials have great potential in the design and application of drug release. The present work: firstly, investigated norfloxacin loading in magnetic metal organic framework (FeO@ZIF-8); and secondly, studied the release of norfloxacin and its antibacterial activity.

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In recent years, graphene oxide (GO)-based multi-responsive actuators have attracted great interest due to their board application in soft robots, artificial muscles, and intelligent mechanics. However, most GO-based actuators suffer from low mechanical strength. Inspired by the natural nacre, a graphene oxide-bacterial cellulose (GO-BC) film with a "brick and mortar" structure is constructed.

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Struvite crystallization is a successful technique for simultaneously recovering PO and NH from wastewater. However, recovering PO and NH from low-concentration solutions is challenging. In this study, PO, NH, and NO were separated and concentrated from wastewater using bipolar membrane electrodialysis, PO and NH can then be recovered as struvite.

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Psoriasis is a chronic skin disease and an important health concern. Western medicine and therapies are the main treatment strategies for psoriasis vulgaris (PV); however, the overall prognosis of patients with PV is still poor. Therefore, PV prevention is especially crucial.

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Background: Ochronotic arthropathy (OcA) is a rare disease, which is caused by the accumulation of homogentisic acid in the joint. Patients with OcA have obvious joint pain and the disease progresses rapidly, eventually resulting in disability. Arthroplasty is an efficacious treatment in patients with OcA.

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Due to its low-cost, eco-friendliness and easy mode of separation biosynthesized magnetic ferroferric oxide (FeO) can be successfully used for the removal of organic contaminants from wastewater. However, there are some challenges that to date have limited this compound's practical removal efficiency. Thus, in this study, a cobalt-based zeolitic imidazole frameworks (ZIF-67) coated biosynthesized ferroferric oxide@silicon dioxide (FeO@SiO) magnetic composite (FeO@SiO/ZIF-67) was prepared to address these issues and subsequently used to remove doxorubicin hydrochloride (DOX).

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The use of biomass for the synthesis of value-added products, such as functional nanomaterial for the removal of contaminants, is a challenge. In this study, hybrid bimetallic Fe/Ni nanoparticles and reduced graphene supported bimetallic Fe/Ni nanoparticles (Fe/Ni-rGO) were prepared via a one-step green synthesis using green tea extract, and thereafter evaluated for the simultaneous removal of rifampicin (RIF) and Pb(II) from aqueous solution. The efficiencies of Pb(II) and RIF removal by Fe/Ni-rGO were 87.

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The increased efflux of fluoroquinolone antibiotics to the environment has become of worldwide concern due to their potential to disturb aquatic ecosystems. How to improve the antibiotic release is a challenge. In this work, magnetic FeO nanoparticles as a drug release vehicle were prepared using the green synthesis method.

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A magnetic field activated drug delivery and pH-sensitive controlled drug release system based on carboxyl-modified green synthesized FeO@SiO (FeO@SiO-Glu) nanoparticles was established. Doxorubicin hydrochloride (DOX), as a drug model, was adsorbed onto the FeO@SiO-Glu nanoparticles' surface, where the observed drug loading capacity of 34.6 mg/g was attributed to electrostatic interaction between -COO on the surface of FeO@SiO-Glu and -NH of DOX.

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Since FeO nanoparticles synthesized by plant extracts possess good bio-compatibility and superparamagnetic properties, the possibility of these could be used as a carrier in drug delivery. In this work, doxorubicin hydrochloride (DOX), an anti-cancer drug, loaded on glutaric anhydride-functionalized magnetic nanoparticles (FeO@SiO-Glu) was investigated at varying pH values for effective drug delivery. Various factors affecting the adsorption of DOX onto the FeO@SiO-Glu were examined, where the adsorption efficiency of DOX reached 92% at a concentration of 20 mg/L employing 10 mg of FeO@SiO-Glu at 303 K in pH 7.

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Antibiotics in water and soil are persistent, bioaccumulative and toxic to aquatic organisms and human health. To address it, as one of the new technologies, green synthesized magnetic FeO nanoparticles by Excoecaria cochinchinensis extract used to remove rifampicin (RIF) was investigated in this study. Results showed the adsorption efficiency of RIF reached 98.

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This study examined functional bentonite-supported nanoscale Fe/Ni (B-Fe/Ni) for the simultaneous removal of β-lactam antibiotics such as amoxicillin (AMX), ampicillin (AMP) and penicillin (PEN). The results show only 94.6% of AMX, 80.

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The aim of this study was to endow an industrial strain of Saccharomyces cerevisiae with the ability to overexpress the xylanase by constructing a homology-driven integration vector. The total mRNA from a xylanase-producing strain of Aspergillus niger IME-216 was extracted and used as the template for the production of endo-β-1,4-xylanase cDNA by reverse transcription. The fusion fragment containing the phosphoglycerate kinase promoter, α-factor signal peptide, xylanase gene encoding the mature peptide, and CYC1 terminator was first generated by overlap extension polymerase chain reaction.

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In this study, a homology-driven integration vector and electroporation system was developed to delete a protease gene in the pathogenic bacterium Brevibacillus laterosporus strain G4. Furthermore, an in vitro protease-deficient mutation was generated by introducing the integration vector with a 445-bp protease BLG4 fragment into B. laterosporus chromosomal target via homologous recombination.

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