Publications by authors named "Wanlin Cui"
Recently, small nucleolar RNAs (snoRNAs) have transcended the genomic "noise" to emerge as pivotal molecular markers due to their essential roles in tumor progression. Substantial evidence indicates a strong association between snoRNAs and critical clinical features such as tumor pathology and drug resistance. Historically, snoRNA research has concentrated on two classical mechanisms: 2'--ribose methylation and pseudouridylation.
View Article and Find Full Text PDFHome phototherapy: an essential component of managing hyperbilirubinaemia.
Lancet Child Adolesc Health
November 2024
Article Synopsis
- Malic enzymes (MEs) convert malate to pyruvate and NAD(P)H, playing significant roles in metabolism and recently being linked to cancer development.
- The review discusses mechanisms through which MEs promote cancer, including various forms of regulation and interactions that affect energy metabolism and immune response.
- It suggests that targeting MEs with small-molecule inhibitors could be a promising therapeutic strategy for cancer treatment, highlighting the need for further research in this area.
Group 2 innate lymphoid cells (ILC2s) expressing IL-5 and IL-13 are localized at various mucosal tissues and play critical roles in the induction of type 2 inflammation, response to helminth infection, and tissue repair. Here, we reveal a unique ILC2 subset in the mouse intestine that constitutively expresses IL-4 together with GATA3, ST2, KLRG1, IL-17RB, and IL-5. In this subset, IL-4 expression is regulated by mechanisms similar to but distinct from those observed in T cells and is partly affected by IL-25 signaling.
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