Pyrazole derivative Z10 ameliorates acute pancreatitis by inhibiting the ERK/Ddt pathway.

Acute pancreatitis (AP) can lead to death; however, there is no specific treatment for AP. Screening of drugs for AP treatment is rarely performed. Compounds were screened in a primary pancreatic acinar cell and peritoneal macrophage coculture system.

The role of community factors in predicting depressive symptoms among Chinese workforce: a longitudinal study in rural and urban settings.

Background: The dual urban-rural division system in China has led to distinguishes in economic development, medical services, and education as well as in mental health disparities. This study examined whether community factors (community cohesion, supportive network size, foreseeable community threat, and medical insurance coverage) predict the depressive symptoms of Chinese workers and how community factors may work differently in rural and urban settings.

Methods: This secondary data analysis was conducted using data from the 2014 and 2016 China Labor-force Dynamics Survey (CLDS).

Internet Public Opinion Diffusion Mechanism in Public Health Emergencies: Based on Entropy Flow Analysis and Dissipative Structure Determination.

As an empirical case, this study selected the illegal production process incidents of rabies and DPT (Diphtheria, Pertussis, Tetanus) vaccines by Changchun Longevity Biotechnology Co., Ltd., which occurred in July 2018.

The C-terminal domain of the type III secretion chaperone HpaB contributes to dissociation of chaperone-effector complex in Xanthomonas campestris pv. campestris.

Many animal and plant pathogenic bacteria employ a type three secretion system (T3SS) to deliver type three effector proteins (T3Es) into host cells. Efficient secretion of many T3Es in the plant pathogen Xanthomonas campestris pv. campestris (Xcc) relies on the global chaperone HpaB.

Depressive symptoms in three Chinese older workforce groups: the interplay of work stress with family and community factors.

Background: More people remain in the workforce into their late life as people's life expectancy increases. This study examined the relationship between work stress and depressive symptoms of older workers in mainland China, focusing on the interplay between work stress with family and community factors in three (i.e.

Serum sphingosine negatively correlates with albumin predicting the risk of hepatocellular carcinoma.

Background: The roles of sphingosine in various cancers have not been fully investigated. Our aim was to identify the relationship between serum sphingosine and the risk of hepatocellular carcinoma (HCC).

Methods: Serum sphingosine in 34 normal people and 73 HCC patients were reviewed retrospectively.

Two lytic transglycosylases of Xanthomonas campestris pv. campestris associated with cell separation and type III secretion system, respectively.

The lytic transglycosylases (LTs) are important enzymes that degrade peptidoglycan of the bacterial cell wall and affect many biological functions. We present here that XC_0706 and XC_3001 are annotated as the LTs in Xanthomonas campestris pv. campestris.

Work Stress and Depressive Symptoms in Chinese Migrant Workers: The Moderating Role of Community Factors.

This study aimed to examine depressive symptoms in ruralurban migrant workers in mainland China, with a focus on the moderating roles of community factors (i.e., community support network, community cohesion and community composition) in the relation between work stress and depressive symptoms.

Differences in depressive symptoms between rural and urban Chinese labor force: The mediating effects of community factors.

Purpose: This study aimed to examine differences in depressive symptoms between urban and rural workers in mainland China and to identify community factors that could contribute to such residential differences.

Methods: This study used nationally representative data from the 2014 China's Labor Force Dynamic Survey. Data were collected through face-to-face interviews on a sample of 22,073 participants from 29 provinces of China, including 15,098 rural workers (Mage = 44.

Dihydroceramide-desaturase-1-mediated caspase 9 activation through ceramide plays a pivotal role in palmitic acid-induced HepG2 cell apoptosis.

In this study, results showed that the inhibition of PA-induced HepG2 cell growth takes place in a time- and concentration-dependent manner, that activation of caspase 9 is necessary for PA-induced HepG2 cell apoptosis, that dihydroceramide desaturase 1 (DES1) plays a key role in PA-mediated caspase 9 and caspase 3 activation, and that palmitoleic acid (POA), an omega-7 monounsaturated fatty acid, reverses PA-induced apoptosis through DES1 → Ceramide → Caspase 9 → Caspase 3 signaling.

[Effects of different light transmission rate on American ginseng's photosynthesis].

From 1997 to 1998, series of experiments were carried out to study American ginseng's photosynthesis related to light transmission rate of plastic cover. The results showed that American ginseng's light saturation point for photosynthesis was different under the different light transmission rate (LTR) because of shading. At about 29.