Catalyst-Free Polymorphic β-GaO Nanomaterials for Solar-Blind Optoelectronic Devices: Applications in Imaging and Neural Communication.

The continuous advancements in ultraviolet-C (UV-C) optoelectronics are poised to meet the growing demand for efficient and innovative optoelectronic devices, particularly in image sensing and neural communication. This study proposes a low-cost tube sealing and muffle calcination process for the catalyst-free synthesis of polymorphic β-GaO nanomaterials. These nanomaterials are synthesized via a vapor-solid (VS) growth mechanism, enabling the formation of high-quality nanowires (NWs), nanobelts (NBs), and nanosheets (NSs).

High-Performance Broad-Spectrum UV Photodetectors with Uniform Response: Engineering β-GaO:Si/GaN:Si Heterojunctions via Thermal Oxidation for Optoelectronic Logic Gate and Multispectral Imaging.

Developing high-performance, broad-spectrum ultraviolet photodetectors (PDs) with uniform response is crucial for optoelectronic applications like spectral analysis, optoelectronic logic gates, and multispectral imaging. This study constructs n-n type β-GaO:Si/GaN:Si heterojunction PDs using thermal oxidation, combining the advantages of β-GaO:Si and GaN:Si for excellent broad-spectrum response (UV-A to UV-C). A proposed channel model for GaN:Si oxidation includes hole formation, vortex structure development, channel formation, and grain growth, providing a basis for understanding β-GaO:Si/GaN:Si heterojunction formation.

Metformin alleviates colitis-associated colorectal cancer via inhibition of the TLR4/MyD88/NFκB/MAPK pathway and macrophage M2 polarization.

Background: Colon inflammation plays an essential role in the development and progression of colorectal cancer. Emerging evidence from clinical and animal studies indicates that metformin may reduce the risk of colorectal cancer through its anti-inflammatory effects.

Aims: To investigate the efficacy of metformin in reducing the risk of colorectal cancer and the possible pathways and mechanisms.

Balancing Carrier Dynamics in Oxygen-Vacancy-Tuned Amorphous GaO Thin-Film Self-Powered Photoelectrochemical-Type Solar-Blind Photodetector Arrays for Underwater Imaging.

Underwater imaging technology plays a pivotal role in marine exploration and reconnaissance, necessitating photodetectors (PDs) with high responsivity, fast response speed, and low preparation costs. This study presents the synergistic optimization of responsivity and response speed in self-powered photoelectrochemical (PEC)-type photodetector arrays based on oxygen-vacancy-tuned amorphous gallium oxide (a-GaO) thin films, specifically designed for solar-blind underwater detection. Utilizing a low-cost one-step sputtering process with controlled oxygen flow, a-GaO thin films with varying oxygen vacancy (V) concentrations are fabricated.

Barrier Polarity Reversal Based on Interfacial Modification of Au Nanoparticles for Nonvolatile Multilevel Memory and Optoelectronic Synapses.

Optoelectronic synaptic devices, integrating light sensing and information processing capabilities, have emerged as advantageous tools for the implementation of visual neuromorphic computing. However, the transient light-triggered response characteristic typically results in unstable memory retention times and restricted current response ranges, posing significant challenges to the development and practical application of neural network systems. In response to these limitations, this study developed a nonvolatile optoelectronic memory based on the indium tin oxide (ITO)/Au nanoparticles (NPs)/amorphous GaO (a-GaO)/Pt structure.

A study on the determination of the metabolites of 2,4,6-Trinitrotoluene using a dual-drift tube ion mobility spectrometer.

2,4,6-Trinitrotoluene (TNT) and its four metabolites, namely 2-ADNT, 4-ADNT, 2,4-DANT, and 2,6-DANT, are highly toxic substances. These metabolites also serve as biomarkers for assessing the health of individuals exposed to TNT. In this study, a homemade DDT-IMS apparatus was utilized to detect these metabolites.

Bismuth Iron Oxide Catalysts for Efficient CO Electroreduction to Formate.

Renewable energy-driven electrocatalytic CO reduction reaction (CORR) over bismuth-based catalysts shows great promise for converting CO into formic acid and formate while closing the carbon cycle. Herein, we report a high-performance BiFeO/BiFeO precatalyst, which delivers a formate partial current density of 359.8 mA cm and a formate formation rate of 6.

Antimicrobial Resistance and New Antimicrobial Agents, A Review of the Literature.

Antibiotic resistance has progressively diminished the effectiveness of conventional antibiotics, necessitating the cessation of clinical treatment. Consequently, novel antibacterial agents are urgently needed. We review studies on antimicrobial agents published during 2002-2023.

Data-Driven Design of Triple-Targeted Protein Nanoprobes for Multiplexed Imaging of Cancer Lymphatic Metastasis.

Targeted imaging of cancer lymphatic metastasis remains challenging due to its highly heterogeneous molecular and phenotypic diversity. Herein, triple-targeted protein nanoprobes capable of specifically binding to three targets for imaging cancer lymphatic metastasis, through a data-driven design approach combined with a synthetic biology-based assembly strategy, are introduced. Specifically, to address the diversity of metastatic lymph nodes (LNs), a combination of three targets, including C-X-C motif chemokine receptor 4 (CXCR4), transferrin receptor protein 1 (TfR1), and vascular endothelial growth factor receptor 3 (VEGFR3) is identified, leveraging machine leaning-based bioinformatics analysis and examination of LN tissues from patients with gastric cancer.

The prognostic value of LAYN in HPV-related head and neck squamous cell carcinoma and its influence on immune cell infiltration.

Background: HPV-positive head and neck squamous cell carcinoma (HNSCC) exhibits different characteristics from HPV-negative tumors in terms of tumor development, clinical features, treatment response, and prognosis. Layilin (LAYN), which contains homology with C-type lectins, plays a critical role in tumorigenesis and cancer progression. However, the prognostic value of LAYN and the relationship between LAYN and immune infiltration levels in HPV-related HNSCC patients still require a comprehensive understanding.

Abstract or concrete? The impact of regional typicality and advertising appeal types on consumption intention toward geographical indication products.

The essential characteristic of geographical indication products is the association of the products with their region of origin. However, consumers have different associations between products and their region of origin (i.e.

Structural insights into histone exchange by human SRCAP complex.

Histone variant H2A.Z is found at promoters and regulates transcription. The ATP-dependent chromatin remodeler SRCAP complex (SRCAP-C) promotes the replacement of canonical histone H2A-H2B dimer with H2A.

Structural visualization of transcription initiation in action.

Transcription initiation is a complex process, and its mechanism is incompletely understood. We determined the structures of de novo transcribing complexes TC2 to TC17 with RNA polymerase II halted on G-less promoters when nascent RNAs reach 2 to 17 nucleotides in length, respectively. Connecting these structures generated a movie and a working model.

SHCBP1 Promotes the Proliferation of Breast Cancer Cells by Inhibiting CXCL2.

Breast cancer has the characteristics of high metastasis and recurrence and ranks first in incidence and mortality among female malignant tumors. Shc SH2-domain binding protein 1 (SHCBP1) is an important protein in intracellular signal transduction and cell division, but the role of SHCBP1 in breast cancers remains elusive. Here, we found that SHCBP1 deficiency inhibited the proliferation of breast cancer cells.

Application of a Core-Shell Structure Nano Filtration Control Additive in Salt-Resistant Clay-Free Water-Based Drilling Fluid.

When drilling into a reservoir, the drilling fluid containing bentonite is prone to solid phase invasion, causing serious damage to the reservoir, and the conventional API barite suspension stability is poor, which makes it easy to cause sedimentation and blockage. Therefore, in order to avoid accidents, we use ultrafine barite to obtain a good suspension stability. More importantly, the method of modifying zwitterionic polymers on the surface of nano-silica is used to develop a temperature-resistant and salt-resistant fluid loss reducer FATG with a core-shell structure, and it is applied to ultra-fine clay-free water-based drilling fluid (WBDF).

Association of sarcopenia and vitamin D deficiency with glucocorticoid-induced osteoporosis in Chinese patients with rheumatoid arthritis.

Objectives: The study aimed to explore the association of sarcopenia and vitamin D deficiency with glucocorticoid-induced osteoporosis (GIOP) in Chinese patients with rheumatoid arthritis (RA).

Method: Skeletal muscle mass, serum 25(OH)D levels, and bone mineral density (BMD) were assessed.

Results: The prevalence of OP, sarcopenia, and vitamin D deficiency in RA patients was significantly higher than in controls (all P < 0.

[Current situation and related of overweight and obesity in children aged 3-6 years old in Urumqi City in 2021].

Objective: To understand the current situation and related factors of overweight and obesity in children aged 3-6 years old in Urumqi City.

Methods: From October to December 2021, a questionnaire survey was conducted on the general information of 1897 children and their fathers or mothers from 10 kindergartens in Urumqi City by stratified cluster sampling, and the height and weight of the children were measured. SPSS 25.

Self-powered Pt/a-GaO/ITO vertical Schottky junction solar-blind photodetector with excellent detection performance.

Self-powered solar-blind photodetectors (PDs) are promising for military and civilian applications owing to convenient operation, easy preparation, and weak-light sensitivity. In the present study, the solar-blind deep-ultraviolet (DUV) photodetector based on amorphous GaO (a-GaO) and with a simple vertical stack structure is proposed by applying the low-cost magnetron sputtering technology. By tuning the thickness of the amorphous GaO layer, the device exhibits excellent detection performance.

Research on a Hybrid Intelligent Method for Natural Gas Energy Metering.

In this paper, a Comprehensive Diagram Method (CDM) for a Multi-Layer Perceptron Neuron Network (MLPNN) is proposed to realize natural gas energy metering using temperature, pressure, and the speed of sound from an ultrasonic flowmeter. Training and testing of the MLPNN model were performed on the basis of 1003 real data points describing the compression factors (Z-factors) and calorific values of the three main components of natural gas in Sichuan province, China. Moreover, 20 days of real tests were conducted to verify the measurements' accuracy and the adaptability of the new intelligent method.

Mortality from cerebrovascular diseases in China: Exploration of recent and future trends.

Background: Cerebrovascular disease (CVD) ranks among the foremost factors responsible for mortality on a global scale. The mortality patterns of CVDs and temporal trends in China need to be well-illustrated and updated.

Methods: We collected mortality data on patients with CVD from Chinese Center for Disease Control and Prevention's Disease Surveillance Points (CDC-DSP) system.

A High-Performance ε-GaO-Based Deep-Ultraviolet Photodetector Array for Solar-Blind Imaging.

One of the most important applications of photodetectors is as sensing units in imaging systems. In practical applications, a photodetector array with high uniformity and high performance is an indispensable part of the imaging system. Herein, a photodetector array (5 × 4) consisting of 20 photodetector units, in which the photosensitive layer involves preprocessing commercial ε-GaO films with high temperature annealing, have been constructed by low-cost magnetron sputtering and mask processes.

Influence of ammonium nitrate on the crystallisation of ammonium sulfate.

This study aims to explore the influence mechanism of ammonium nitrate produced by ozone denitrification on the crystallisation of ammonium sulfate, a by-product of ammonia desulfurisation. The laser method was used to study the influence of ammonium nitrate on the solubility and metastable zone width of ammonium sulfate. An experiment on the influence of ammonium nitrate on the particle size of ammonium sulfate was designed, and the influence mechanism was explored through scanning electron microscopy and X-ray diffraction.

CO + NH coupling denitration at low temperatures over manganese/activated carbon catalysts.

To explore the mechanism of low-temperature carbon monoxide and ammonia (CO + NH) coupling denitration of manganese/activated carbon (Mn/AC) catalysts, Mn/AC series catalysts were prepared using the impregnation method with AC activated by nitric acid as a precursor and manganese nitrate as a precursor. We characterized the surface morphology, pore structure, active component phase, functional group, and active component valence change law of the Mn/AC catalyst. The denitration rate order with different Mn loadings is 7Mn/AC > 9Mn/AC > 5Mn/AC.

Structure of nucleosome-bound human PBAF complex.

BAF and PBAF are mammalian SWI/SNF family chromatin remodeling complexes that possess multiple histone/DNA-binding subunits and create nucleosome-depleted/free regions for transcription activation. Despite previous structural studies and recent advance of SWI/SNF family complexes, it remains incompletely understood how PBAF-nucleosome complex is organized. Here we determined structure of 13-subunit human PBAF in complex with acetylated nucleosome in ADP-BeF-bound state.