Publications by authors named "Wanjun Hao"

The enhancement of the utilization rate of solid waste, along with balancing the comprehensive performance of materials, presents a significant challenge in the development of new functional building materials. This study examined the effects of high concentrations of iron tailing powder on the crystallization characteristics, pore structure, compressive strength, and water absorption of modified magnesium oxysulfate (MOS) foam cement with different dry densities. Furthermore, employing chemical foaming technology, the study characterized and analyzed the microstructure of modified MOS foam cement hydration products through scanning electron microscopy (SEM) and X-ray diffraction analysis (XRD).

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MicroRNAs play essential roles in biological processes by regulating gene expression at the post-transcriptional level. Our previous studies suggested the role of miR-26a in porcine fat accumulation. Here, through gain- and loss-of-function analyses, we first showed that miR-26a increased the proliferation of porcine preadipocytes by promoting cell division and that miR-26a inhibited the preadipocyte differentiation.

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Long-chain acyl-CoA synthetase 1 (ACSL1) plays an important role in fatty acid metabolism and fat deposition. The transcription of the gene is regulated specifically among cells and physiological processes, and transcriptional regulation of in adipogenesis remains elusive. Here, we characterize transcription factors (TFs) associated with adipogenesis in the porcine gene.

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The need to reach carbon neutrality as soon as possible has made the use of recycled materials widespread. However, the treatment of artificial marble waste powder (AMWP) containing unsaturated polyester is a very challenging task. This task can be accomplished by converting AMWP into new plastic composites.

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Developing flame-retarded styrene-acrylic emulsion (SAE) based damping composites is a challenging task because of their very high flammability. A promising approach is the synergistic combination of expandable graphite (EG) and ammonium polyphosphate (APP). In this study, the surface modification of APP was modified by commercial titanate coupling agent ndz-201 through ball milling, and the SAE-based composite material was prepared with SAE and different ratios of modified ammonium polyphosphate (MAPP) and EG.

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Development from single cells to multicellular tissues and organs involves more than just the exact replication of cells, which is known as differentiation. The primary focus of research into the mechanism of differentiation has been differences in gene expression profiles between individual cells. However, it has predominantly been conducted at low throughput and bulk levels, challenging the efforts to understand molecular mechanisms of differentiation during the developmental process in animals and humans.

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Chimeric RNA is a crucial target for tumor diagnosis and drug therapy, also having its unique biological role in normal tissues. (), a chimeric RNA discovered by our laboratory in porcine muscle tissue, can inhibit the proliferation of Porcine Skeletal Muscle Satellite Cells (PSCs). The regulatory mechanism of in PSCs remains unclear, but we speculate that and may be the target genes of .

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The cAMP response element-binding protein (CREB), a basic leucine zipper transcription factor, is involved in the activation of numerous genes in a variety of cell types. The gene is rich in alternative splicing (AS) events. However, studies on the AS of genes in pigs are limited, and few reports have compared the roles of isoforms in activating gene expression.

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Developing photoelectrochemical biosensors efficient photogenerated-charge separation remains a challenging task in biomolecular detection. In this study, we utilised a simple approach for constructing an efficient photoactive organic-inorganic heterojunction interface composed of SrTiO with high photocatalytic activity and polydopamine (PDA) with high biocompatibility and electrical conductivity. Gold nanoparticles with dense electron cloud properties were introduced as a bridge between SrTiO and PDA (SrTiO/Au/PDA).

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-Splicing of adjacent genes (-SAGe) has been involved in multiple physiological and pathological processes in humans. However, to the best of our knowledge, there is no report of -SAGe in adipogenic regulation. In this study, a -SAGe product, BCL2L2-PABPN1 (BP), was characterized in fat tissue of pigs with RT-PCR and RACE method.

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Meat quality is one of the most important economic traits in pig breeding and production. Intramuscular fat (IMF) is a major factor that improves meat quality. To better understand the alternative splicing (AS) events underlying meat quality, long-read isoform sequencing (Iso-seq) was used to identify differential (D)AS events between the longissimus thoracis (LT) and semitendinosus (ST), which differ in IMF content, together with short-read RNA-seq.

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Chimeric RNA was considered a special marker of cancer. However, recent studies have demonstrated that chimeric RNAs also exist in non-cancerous cells and tissues. Here, we analyzed and predicted jointly 49 chimeric RNAs by Star-Fusion and FusionMap.

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Recent achievements in the field of computer vision, reinforcement learning, and locomotion control have largely extended legged robots' maneuverability in complex natural environments. However, little research focuses on sensing and analyzing the physical properties of the ground, which is crucial to robots' locomotion during their interaction with highly irregular profiles, deformable terrains, and slippery surfaces. A biomimetic, flexible, multimodal sole sensor (FMSS) designed for legged robots to identify the ontological status and ground information, such as reaction force mapping, contact situation, terrain, and texture information, to achieve agile maneuvers was innovatively presented in this paper.

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Hydrogel hybrids are one of the key factors in life activities and biomimetic science; however, their development and utilization are critically impeded by their inadequate adhesive strength and intricate process. In nature, barnacles can stick to a variety of solid surfaces firmly (adhesive strength above 300 kPa) using a hydrophobic interface, which inspires us to firmly combine hydrogels and polymers through introducing an adhesive layer. By spreading a hydrophobic liquid membrane directly, tough combination of a hydrogel and a polymer substrate could be achieved after one-step polymerization.

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Ultra-high sensitivity is difficult to achieve using conventional enzymatic glucose biosensors due to the lack of exposed active sites and steric-hinderance effects. Thus, in the present study, we report a photoelectrochemical (PEC) enzymatic glucose biosensor based on 3-dimensional (3D) hollow-out titanium dioxide (TiO) nanowire cluster (NWc)/glucose oxidase (GOx), providing more number of exposed active sites, thus constructing a sensor with a higher affinity toward glucose reaction. Excellent performance with an ultra-high sensitivity of 58.

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Article Synopsis
  • - C1QBP is a receptor involved in immune responses, and its secretion increases during PRRSV infection in certain cells, including Marc-145 and porcine alveolar macrophages.
  • - Previous research revealed that PRRSV infection leads to elevated C1QBP levels, but its exact role was not well understood until this study.
  • - The study found that reducing C1QBP decreased inflammatory responses, while adding purified C1QBP boosted inflammation, highlighting its role in mediating immune reactions during PRRSV infection.
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Lipids play a crucial role in the replication of porcine reproductive and respiratory syndrome virus (PRRSV), a porcine virus that is endemic throughout the world. However, little is known about the effect of fatty acids (FAs), a type of vital lipid, on PRRSV infection. In this study, we found that treatment with a FA biosynthetic inhibitor significantly inhibited PRRSV propagation, indicating the necessity of FAs for optimal replication of PRRSV.

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To understand genetic background and phylogenetic position of , we determined its complete chloroplast genome sequence which is 157,026 bp in length with overall GC content of 36.7%. It has four sub regions: a large single-copy (LSC) region (86,669 bp) and a small single-copy (SSC) region (18,253 bp) are separated by two inverted repeat (IR) regions (26,052 bp each).

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For obtaining the sequence and phylogenetic position of cultivar 'Baiye1', the complete chloroplast genome was determined. This chloroplast genome is 156,691 bp in length with overall GC content of 37.3%.

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Article Synopsis
  • - The study investigates CsWRKY7, a transcription factor in tea plants that responds to various environmental stresses and may influence plant development, revealing its genetic homology with Arabidopsis.
  • - CsWRKY7 is located in the nucleus and shows increased expression in response to stress treatments (like NaCl and mannitol), indicating its role in stress response and growth regulation.
  • - Transgenic Arabidopsis overexpressing CsWRKY7 demonstrates delayed flowering and altered expression of flowering-related genes, suggesting that this transcription factor could be leveraged to breed late-blooming tea cultivars.
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Cytoplasmic effects (CEs) have been discovered to influence a diverse array of agronomic traits in crops, and understanding the underlying mechanisms can help accelerate breeding programs. Seed oil content (SOC) is of great agricultural, nutritional, and economic importance. However, the genetic basis of CEs on SOC (CE-SOC) remains enigmatic.

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Understanding the genetic basis of theobromine and caffeine accumulation in the tea plant is important due to their contribution to tea flavor. Quantitative trait loci (QTL) analyses were carried out to identify genetic variants associated with theobromine and caffeine contents and ratio using a pseudo-testcross population derived from an intervarietal cross between two varieties of Camellia sinensis. A total of 10 QTL controlling caffeine content (CAF), theobromine content (TBR), sum of caffeine and theobromine (SCT), and caffeine-to-theobromine ratio (CTR) were identified over four measurement years.

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Catechins are important chemical components determining the quality of tea. The catechin index (CI, ratio of dihydroxylated catechin (DIC)/trihydroxylated catechin (TRIC)) in the green leaf has a major influence on the amounts of theaflavins in black tea. In this work, the major catechin profiles of wild tea plants originating from Guizhou Province with high CI trait were investigated.

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Tea plant (Camellia sinensis (L) O. Kuntze) respond to herbivore attack through large changes in defense related metabolism and gene expression. Ectropis oblique (Prout) is one of the most devastating insects that feed on tea leaves and tender buds, which can cause severe production loss and deteriorate the quality of tea.

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Self-healing hydrogels have a great potential application in 3D printing, soft robotics, and tissue engineering. There have been a large number of successful strategies for developing hydrogels that exhibit rapid and autonomous recovery. However, developing a gel with an excellent self-healing performance within several seconds is still an enormous challenge.

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