Low-voltage efficient electroosmotic pumps with ultrathin silica nanoporous membrane.

In this work, an efficient electroosmotic pump (EOP) based on the ultrathin silica nanoporous membrane (u-SNM), which can drive the motion of fluid under the operating voltage as low as 0.2 V, has been fabricated. Thanks to the ultrathin thickness of u-SNM (∼75 nm), the effective electric field strength across u-SNM could be as high as 8.

Highly Efficient Desalting by Silica Isoporous Membrane-Based Microfluidic Chip for Electrospray Ionization Mass Spectrometry.

Nonvolatile buffers and inorganic salts used for isolation and stabilization of biological samples are essential to be cleaned up prior to mass spectrometry (MS) analysis because of their deleterious effects such as ion suppression and instrumental pollution. In this work, a centimeter-scale continuous silica isoporous membrane (SIM) was prepared and integrated into a facile microfluidic chip for the desalting of protein samples based on dialysis principle. Thanks to the uniform pore size (∼2.

pH-Controlled Drug Release by Diffusion through Silica Nanochannel Membranes.

We report in this work the fabrication of a flow-through silica nanochannel membrane (SNM) for controlled drug release applications. The ultrathin SNM consists of parallel nanochannels with a uniform diameter of ∼2.3 nm and a density of 4 × 10 cm, which provide simultaneously high permeability and size selectivity toward small molecules.