Single-cell RNA Sequencing Identifies Natural Kill Cell-Related Transcription Factors Associated With Age-Related Macular Degeneration.

Background: Age-related Macular Degeneration (AMD) poses a growing global health concern as the leading cause of central vision loss in elderly people.

Objection: This study focuses on unraveling the intricate involvement of Natural Killer (NK) cells in AMD, shedding light on their immune responses and cytokine regulatory roles.

Methods: Transcriptomic data from the Gene Expression Omnibus database were utilized, employing single-cell RNA-seq analysis.

Use of β‑blockers and risk of age‑related macular degeneration among hypertensive patients: An insight from The National Health and Nutrition Examination Survey.

Although age-related macular degeneration (AMD) is the leading cause of legal blindness, the treatment methods for AMD are limited. The aim of the present study was to examine the association between oral β-blockers (BBs) and the risk of developing AMD among hypertensive patients. For this purpose, a total of 3,311 hypertensive patients from the National Health and Nutrition Examination Survey were included in the study.

Evaluation of choroidal thickness in amblyopia using optical coherence tomography.

Objective: To investigate the choroidal thickness in children with amblyopia through spectral-domain optical coherence tomography.

Methods: A total of 31 children with unilateral amblyopia and 31 right eyes of controls with normal vision were enrolled in the study. The choroidal thickness was measured directly below the fovea and at 12 other locations: 1, 2 and 3 mm superior, temporal, inferior, and nasal to the fovea.

Axial Length and Ocular Development of Premature Infants without ROP.

Purpose: To investigate the ocular parameters of premature infants without ROP at gestational age (GA) more than 28 weeks and their relationship with growth parameters.

Methods: 76 preterm infants without ROP and 65 term infants were involved to undergo portable slit lamp, RetCam3, ultrasonic A-scan biometry, and cycloplegic streak examination at their 40 weeks' postconceptional ages (PCA). Ocular parameters of infants' right eye and growth parameters were used for analysis.

Evaluation of myopia on retinal nerve fiber layer thickness measured by Spectralis optical coherence tomography.

The aim of the present study was to evaluate the retinal nerve fiber layer (RNFL) thickness of myopic subjects using Spectralis optical coherence tomography (OCT) and to determine variations with age and sex. A total of 271 Chinese participants with a spherical equivalent <+0.50 diopters were enrolled in the research.

[Evaluation of Orbscan II plus non-history double-K method in intraocular lens power calculation for patients after refractive surgery].

Objective: To explore the accuracy of intraocular lens (IOL) power calculation with non-history method using the keratometric value derived from one zone of Orbscan II topography after laser in situ keratomileusis (LASIK).

Methods: For this retrospective study, 20 eyes from 20 patients undergoing myopic LASIK were included from August 2008 to November 2011. Posterior corneal curvature in peripheral 7 to 10 mm fitting zone of postoperative cornea was measured with Orbscan II topography.

Evaluation of myopic corneal diameter with the Orbscan II Topography System.

Background: To assess the myopic corneal diameter with Orbscan II Topography System (Bausch & Lomb, Orbtek Inc., Salt Lake City, UT, USA).

Methods: Four hundred sixty-two eyes of 231 myopic patients and 129 emmetropic eyes were measured with the Orbscan II system.