Phomaligol J, A New Cyclohexenone with Antibacterial Activity from a Pufferfish Associated Fungus Aspergillus austwickii.

A new cyclohexenone, phomaligol J (1), along with 9 known compounds (2-10) was isolated from the liquid culture of the pufferfish associated Aspergillus austwickii collected from Yangma Island, Yantai. Their structures were determined by extensive spectroscopic data analysis, HRESIMS, electronic circular dichroism (ECD) and the comparison with reported data in the literature. In bioactivity, all isolated compounds were evaluated for antibacterial activity against 12 bacterial strains.

[Study on musculuskeletal ultrasound features and correlation of knee osteoarthritis].

Objective: To compare the correlation between musculoskeletal ultrasound features, dysfunction and X-ray findings in patients with knee osteoarthritis, and to analyze the pathological mechanism of soft tissue inflammation in knee osteoarthritis.

Methods: Cross-sectional method was performed in this research (Evidence level: III). The patients with knee osteoarthritis were collected according to the screening criteria from September 2016 to January 2017 in Orthopedic clinic in our hospital.

[Analysis of the relationship between living habit and cervical instability in adolescent patients with neck pain].

Objective: To investigate the relationship between living habit and cervical instability in adolescent patients with neck pain.

Methods: Fifty-nine adolescent patients with neck pain(neck pain group) and seventeen healthy teenagers (control group) were recruited and divided into two groups, and clinical information, living habit were collected. In addition, all people were taken lateral, hyperextension and hyperflexion radiography to analyze relationship between living habit and cervical instability.