Publications by authors named "Wang-Qing Shi"
Article Synopsis
- Esophageal cancer is a highly lethal disease, often diagnosed too late for effective treatment due to poor early detection methods.
- This study evaluated the use of specific autoantibodies linked to stem cell signatures, especially focusing on SOX2, to enhance early diagnosis and predict patient outcomes.
- Results showed that the highlighted antibodies, particularly SOX2, exhibited promising diagnostic sensitivity and specificity for early-stage esophageal cancer, indicating their potential as valuable diagnostic tools.
Background: The small tyrosine kinase inhibitors (TKIs) subversively altered the lung cancer treatments, but patients will inevitably face the therapy resistance and disease recurrence. We aim to explore the potential roles of non-coding RNAs in sensitizing the TKIs effects.
Methods: Multiple cellular and molecular detections were applied to confirm the mechanistic regulations and intracellular connections.
[The expression of bFGF, GAP-43 and neurogenesis after cerebral ischemia/reperfusion in rats].
Zhongguo Ying Yong Sheng Li Xue Za Zhi
January 2013
Objective: To observe time points of the expressions of basic fibroblast growth factor (bFGF), growth associated protein-43 (GAP-43) and neurogenesis after cerebral ischemia/reperfusion in rats and explore its possible mechanism of neurogenesis.
Methods: Models of middle cerebral artery occlusion (MCAO) were established in SD rats which were divided into 3 d, 7 d, 14 d and 28 d groups (n = 6). The neurological severity was evaluated by neurological severity scores (NSS) and scores of motor test (SMT).
This study is to observe the effect of ilexonin A (IA) on the expression of basic fibroblast growth factor (bFGF) and growth associated protein-43 (GAP-43), and neurogenesis after cerebral ischemia-reperfusion in rats and explore its possible mechanism of protecting neuronal injury. Models of middle cerebral artery occlusion (MCAO) were established in SD rats. Before and after two hours ischemia-reperfusion, IA (20 and 40 mg x kg(-1)) was injected immediately and on 3, 7, 14, and 28 d once a day.
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