Association of inflammation cytokines with cognitive function in first-episode major depressive disorder.

Objective: Abnormal cognitive functioning is a core symptom of Major Depressive Disorder (MDD) and is strongly correlated with MDD prognosis. Current studies suggest that the occurrence of MDD may be related to oxidative stress-induced inflammation, hypothalamic-pituitary-adrenal axis disorders, diminished monoamine function and microbe-brain-gut axis, among other pathways. In recent years, the relationship between the immune-inflammatory response and MDD has been a hot topic of research, but how the relationship between immunoinflammation and cognitive function is manifested in MDD is still unclear.

Positivity and Boundedness Preserving Numerical Scheme for a Stochastic Multigroup Susceptible-Infected-Recovering Epidemic Model with Age Structure.

Since the stochastic age-structured multigroup susceptible-infected-recovering (SIR) epidemic model is nonlinear, the solution of this model is hard to be explicitly represented. It is necessary to construct effective numerical methods so as to predict the number of infections. In addition, the stochastic age-structured multigroup SIR model has features of positivity and boundedness of the solution.

Risk assessment and pathogen profile of surgical site infections in traumatic brain injury patients undergoing emergency craniotomy: A retrospective study.

Emergency craniotomy in patients with traumatic brain injury poses a significant risk for surgical site infections (SSIs). Understanding the risk factors and pathogenic characteristics of SSIs in this context is crucial for improving outcomes. This comprehensive retrospective analysis spanned from February 2020 to February 2023 at our institution.

Positivity-Preserving Numerical Method and Relaxed Control for Stochastic Susceptible-Infected-Vaccinated Epidemic Model with Markov Switching.

The stochastic susceptible-infected-vaccinated (SIV) epidemic model includes a nonlinear term, making it difficult to obtain analytical solutions. Thus, numerical approximation schemes are an important tool for predicting the dynamics of infectious diseases and establishing optimal control strategies. However, the convergence rate of the existing numerical methods [e.

Detection method and instrument of interfacial debonding inside a thermal barrier coating based on fluorescence imaging.

The interfacial delamination or debonding induced by local stress concentration is one of the kernel factors leading to spalling failure of thermal barrier coatings (TBC). In this work, for the rapid and accurate characterization of the interface delamination and debonding in TBC, the detection method and instrument were investigated based on fluorescence imaging. First, based on the principle of reflection-enhanced fluorescence, an experimental method was presented to detect interfacial debondings in TBC.

Planted forest is catching up with natural forest in China in terms of carbon density and carbon storage.

Over the last several decades, China has taken multiple measures for afforestation and natural forest protection, including setting the goal of carbon neutrality by the middle of 21th century. In order to support the practice of relevant policies from the scientific perspective, it is essential to precisely estimate the carbon storage of arbor forest, as it plays an important role in the carbon cycle of ecosystems. In this study, we first used the latest four phases of national forest inventory data to investigate the variation of carbon storage for both natural and planted arbor forest in China during the covered period (1999-2018).

Giant dumbbell-shaped prostatic cystadenoma presenting as pelvic and scrotal mass.

This study reports the case of an elderly man with a large tumour of the pelvic cavity and scrotum which was once diagnosed as a prostate cyst. Imaging studies considered the source of the tumour to be prostate, and the tumour was ultimately diagnosed by confirmed tissue expression of prostate specific antigen (PSA) and prostate acid phosphatase (PSAP) after surgery. This is the first report about dumbbell-shaped prostatic cystadenoma with invasive growth and even urethral damage, but there was no evidence of clear malignancy.

Tumor Suppressor microRNA-138 Suppresses Low-Grade Glioma Development and Metastasis via Regulating IGF2BP2.

Background: Low-grade gliomas (LGG), approximately constitute one-third of all types of gliomas, are prone to relapse and metastasis. MicroRNA-138 (miR-138) is reported to be dysregulated in diverse human tumors and mainly function as a tumor suppressor. In this study, we analyzed the expression profile and function of miR-138 in LGG.

LncRNA SNHG1 Regulates the Progression of Esophageal Squamous Cell Cancer by the miR-204/HOXC8 Axis.

Objective: Long noncoding RNA small nucleolar RNA host gene 1 (SNHG1) has been reported to be aberrantly expressed and plays an important role in human cancers, including esophageal squamous cell cancer. However, the regulatory mechanism underlying SNHG1 in the progression of esophageal squamous cell cancer is poorly defined.

Materials And Methods: Fifty-three esophageal squamous cell cancer patients were recruited and overall survival was analyzed.

Markovian switching for near-optimal control of a stochastic SIV epidemic model.

As it is known that environmental perturbation is a key component of epidemic models, and Markov process reveals how the noise affects epidemic systems. The paper introduces Markov chain into a stochastic susceptible-infected-vaccination(SIV) epidemic model composed of vaccination and saturated treatment to analyze the near-optimal control. Based on Pontryagin stochastic maximum principle, the paper gives adequate and all necessary conditions for near-optimal control.

Assessment of the eco-environmental quality in the Nanweng River Nature Reserve, Northeast China by remote sensing.

Scientific and rapid assessment of the ecological environment quality based on remote sensing can provide basis for regional protection, management and planning. In this study, using Landsat TM/OLI/TIRS in 1990, 2000 and 2015 as data sources, four indices including the wetness component of the tasseled cap transformation (WET), normalized difference vegetation index (NDVI), normalized difference built-up and soil index (NDSI), and land surface temperature (LST) were derived, with the weights being determined by principal components analysis (PCA). Remote sensing ecological index (RSEI) was used to evaluate the eco-environmental quality of Nanweng River Nature Reserve from 1990 to 2015.

ZEB1-mediated vasculogenic mimicry formation associates with epithelial-mesenchymal transition and cancer stem cell phenotypes in prostate cancer.

The zinc finger E-box-binding homeobox 1 (ZEB1) induced the epithelial-mesenchymal transition (EMT) and altered ZEB1 expression could lead to aggressive and cancer stem cell (CSC) phenotypes in various cancers. Tissue specimens from 96 prostate cancer patients were collected for immunohistochemistry and CD34/periodic acid-Schiff double staining. Prostate cancer cells were subjected to ZEB1 knockdown or overexpression and assessment of the effects on vasculogenic mimicry formation in vitro and in vivo.

[Dynamics of habitat suitability for waterfowls from 1990 to 2015 in the ecological function zone of Sanjiang Plain, Northeast China].

As a wetland of international importance, the ecological function zone of the Sanjiang Plain (EFZSP) plays an important role in maintaining waterfowl habitat. With the increasing disturbance of human beings, land use and climate changes, habitat suitability for waterfowls (HSW) has drawn greater attention of ecologists. In this study, Landsat TM/ETM+/OLI and HJ-1B images in 1990, 2000, 2010 and 2015 were used to obtain land cover classification by object-based image analysis, and the entropy and analytic hierarchy process methods were adopted to determine the factors and their weights, the factors selected in this study included water condition (lake and river density), disturbance factor (residence and road density), shelter condition (land cover type and slope), and food abundance (NDVI).

ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice.

Background & Aims: The ARID1A gene encodes a protein that is part of the large adenosine triphosphate (ATP)-dependent chromatin remodeling complex SWI/SNF and is frequently mutated in human pancreatic ductal adenocarcinomas (PDACs). We investigated the functions of ARID1A during formation of PDACs in mice.

Methods: We performed studies with Ptf1a-Cre;Kras mice, which express activated Kras in the pancreas and develop pancreatic intraepithelial neoplasias (PanINs), as well as those with disruption of Aird1a (Ptf1a-Cre;Kras;Arid1a mice) or disruption of Brg1 (encodes a catalytic ATPase of the SWI/SNF complex) (Ptf1a-Cre;Kras; Brg1mice).

Long non-coding RNA XIST exerts oncogenic functions in human glioma by targeting miR-137.

Long non-coding RNA (lncRNA) X inactivate-specific transcript (XIST) acts as an important regulator in tumor progression. However, its expression and the underlying mechanism in glioma remain unclear. The aim of this study was to explore the potential function of XIST in glioma progression.

Surface modeling of soil antibiotics.

Large numbers of livestock and poultry feces are continuously applied into soils in intensive vegetable cultivation areas, and then some veterinary antibiotics are persistent existed in soils and cause health risk. For the spatial heterogeneity of antibiotic residues, developing a suitable technique to interpolate soil antibiotic residues is still a challenge. In this study, we developed an effective interpolator, high accuracy surface modeling (HASM) combined vegetable types, to predict the spatial patterns of soil antibiotics, using 100 surface soil samples collected from an intensive vegetable cultivation area located in east of China, and the fluoroquinolones (FQs), including ciprofloxacin (CFX), enrofloxacin (EFX) and norfloxacin (NFX), were analyzed as the target antibiotics.

Kidney failure associated with liver transplantation or liver failure: the impact of continuous veno-venous hemofiltration.

Background And Aims: The short-term outcome of critically ill patients with kidney failure combined with severe liver failure or orthotopic liver transplantation (OLTx) is poor. We sought to test the hypothesis that, with the exclusive use of continuous veno-venous hemofilration (CVVH) with minimal heparin-anticoagulation, the short and long-term outcomes of these patients would be improved.

Patients: Sixty-six consecutive patients with combined liver and kidney failure

Setting: Intensive Care Unit of tertiary hospital

Design: Retrospective interrogation of prospectively collected databases

Intervention: Treatment of all patients with continuous veno-venous hemofiltration (CVVH) by protocol with 2L/h of ultrafiltration rate and minimal use of circuit heparinization.