Publications by authors named "Wang Youming"

Objective: To describe the clinical characteristics, therapeutic approaches, and prognostic outcomes of osmotic demyelination syndrome (ODS) in cancer patients.

Methods: A comprehensive literature search (January 1950-March 2024) using PubMed, Embase, Cochrane Library, and Web of Science. Keywords included "osmotic demyelination and cancer", "central pontine myelinolysis and cancer", and "extrapontine myelinolysis and cancer", "Osmotic demyelination and malignancy," "Central pontine myelinolysis and malignancy," and "Extrapontine myelinolysis and malignancy.

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Brucellosis, caused by spp., is a re-emerging One Health disease with increased prevalence and incidence in Chinese dairy cattle and humans, severely affecting animal productivity and public health. In dairy cattle, is the primary causative agent although infections with other species occur occasionally.

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Article Synopsis
  • Chemoresistance is a big problem for treating a type of blood cancer called acute myeloid leukemia (AML), making it hard for treatments to work effectively.
  • Scientists found that a special channel in cells, called TRPML1, was more active in AML cells, and shutting it down could help make the cancer cells more sensitive to chemotherapy.
  • Doing this not only helped the chemotherapy work better but also reduced tumor growth in mouse experiments, suggesting targeting TRPML1 could be a useful part of cancer treatment.
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Bovine brucellosis, primarily caused by Brucella abortus, severely affects both animal health and human well-being. Accurate diagnosis is crucial for designing informed control and prevention measures. Lacking a gold standard test makes it challenging to determine optimal cut-off values and evaluate the diagnostic performance of tests.

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Avian influenza scare is a human psychological factor that asserts both positive and negative effects on the transmission of zoonotic avian influenza. In order to study the dichotomous effect of avian influenza scare on disease transmission, taking H7N9 avian influenza as a typical case, a two-patch epidemic model is proposed. The global dynamics and the threshold criteria are established by LaSalle invariant principle and the theory of asymptotic autonomous system.

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Chimeric antigen receptor (CAR)-modified T cells have demonstrated remarkable efficacy in treating B-cell leukemia. However, treated patients may potentially develop side effects, such as cytokine release syndrome (CRS), the mechanisms of which remain unclear. Here, we collected 43 serum samples from eight patients with B-cell acute lymphoblastic leukemia (B-ALL) before and five time points after CD19-specific CAR-T cell treatment.

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is one of the most important pathogens affecting pig production worldwide. It can be also transmitted to human through the behaviors of eating undercooked pork or slaughtering sick pigs. A meta-analysis was conducted to estimate the prevalence across different geographical areas in China.

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The neuroprotection of acute cerebral infarction (ACI) model by edaravone dexborneol (ED)-mediated Keap1-Nrf2/ARE signal pathway was investigated. Sham operation was set as a control to prepare the ACI model with cerebral artery occlusion. The abdominal cavity was injected with edaravone (ACI+Eda group) and ED (ACI+ED group).

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Glycerol is an ideal co-substrate for xylitol production with Kluyveromyces marxianus. This study demonstrated that K. marxianus catabolizes glycerol through the Gut1-Gut2 pathway instead of the previously speculated NADPH-dependent Gcy1-Dak1 pathway using the transient clustered regularly interspaced short palindromic repeats/ CRISPR-associated protein 9 (CRISPR/Cas9) system.

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and are dominant species of Chinese house rats, but the colonization and demographic history of two species in China have not been thoroughly explored. Phylogenetic analyses with mitochondrial DNA including 486 individuals from 31 localities revealed that is widely distributed in China, is mainly distributed in southern China with currently invading northward; northeast China was the natal region of , while the spread of in China most likely started from the southeast coast. A total of 123 individuals from 18 localities were subjected to 2b-RAD analyses.

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Pseudorabies virus (PRV) is a common pathogen found in pigs. The pathogenicity of PRV in humans is under researched and there are few confirmed cases of PRV infections in humans, which has led to a lack of clinical consensus. We presented a case of viral encephalitis caused by PRV in China.

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Thermal compensation control can correct errors caused by the thermal deformation of phased array antenna (PAA) panels. Thermal deformation of the panel is needed to calculate the compensation value. While the PAA is working, thermal deformation is unconditional to measure, but predicting it by temperature is feasible.

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The influenza A virus of the H7N9 subtype (FLUAV H7N9) emerged in Eastern China provinces in 2013 causing illness in both poultry and humans. Most reported FLUAV H7N9 human cases were related to those associated with the live poultry market chain. From 2013 to 2017, there were five epidemic waves of human infections, and from the end of 2016, the number of human cases increased sharply.

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In this paper, a joint communication interference integration signal waveform is proposed to satisfy the need of electronic system integration in civil and military uses, and mitigate the tension of spectrum resource. We design the system structure of the integrated signal model and propose the communication receiving processing flow of the integrated system. We utilize the dense false-target jamming style to raise the constant false alarm rate detection threshold via the delay superposition of multiple groups of frequency modulation (FM) slope mismatch jamming signals, which can play a role in protecting our target from being detected.

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China launched a H7N9 vaccination program in poultry, starting from the Guangxi and Guangdong provinces in July 2017, followed by other provinces in September 2017, as a response to a steep increase of H7N9 influenza human infections from September 2016. Since then, H5-H7 bivalent vaccine has been used in the nationwide avian influenza compulsory vaccination program to replace the existing H5N1 vaccine. However, the economic returns of the H7N9 vaccination program in China have never been adequately assessed.

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The data volume and computation task of MIMO radar is huge; a very high-speed computation is necessary for its real-time processing. In this paper, we mainly study the time division MIMO radar signal processing flow, propose an improved MIMO radar signal processing algorithm, raising the MIMO radar algorithm processing speed combined with the previous algorithms, and, on this basis, a parallel simulation system for the MIMO radar based on the CPU/GPU architecture is proposed. The outer layer of the framework is coarse-grained with OpenMP for acceleration on the CPU, and the inner layer of fine-grained data processing is accelerated on the GPU.

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Most Chinese provinces have a daily-updated database of live animal movements; however, the data are not efficiently utilized to support interventions to control H7N9 and other avian influenzas. Based on official records, this study assessed the spatio-temporal patterns of live broilers moved out of and within Guangxi in 2017. The yearly and monthly networks were analyzed for inter- and intra-provincial movements, respectively.

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Since the outbreak of African swine fever (ASF) in Shengyang, it has continued spreading in China. In the early stage of the epidemic, multi-point and concentrated outbreaks were mainly in the swill feeding areas. In this paper, we developed compartmental models to investigate the transmission of ASF in several raising units including Guquan, Jinba and Liancheng.

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In response to a sudden increase in H7N9 human infections, China introduced an H5/H7 bivalent inactivated vaccine for poultry in Guangxi and Guangdong provinces in July 2017, which subsequently became integrated into the existing compulsory national H5N1 vaccination programme from September 2017. Although the vaccination programme effectively reduced H7N9 infections in humans and poultry, there are ongoing arguments against continuing this long-term vaccination. These discussions have drawn policymakers to think about the possibility of stopping routine vaccination for H7N9 avian influenza viruses (AIVs) in China; however, they have not considered the poultry industry stakeholders' practices on and attitudes towards this vaccination.

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African swine fever virus (ASFV) leads to a highly contagious, lethal and economically devastating disease among pigs. Since no effective treatment for the disease, it is crucial to investigate its transmission mechanism and control strategies in large-scale pig farms. We first established a toy model to explore ASFV spread in one pig unit.

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Yellow broilers are the primary source of poultry consumption in China and the predominant trade of live poultry. However, knowledge of the value chain is limited, which is vital evidence for the effective control of H7N9 and other zoonotic avian influenzas. The aim of the study was to map the yellow broiler value chain in Guangxi Zhuang Autonomous Region, China and investigate its governance structure and practices relevant to the risk of H7N9 transmission.

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As of 21 April 2020, 176 ASF outbreaks have occurred in China. For each outbreak, an investigation was conducted, including historical data retrieval and traceability of potential contacts. The purpose of this study is to conduct a preliminary analysis of the data obtained from the outbreak investigations, including an investigation of the possible contributing factors of the spread of ASF in China.

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In China, foot-and-mouth disease (FMD) serotype O remains prevalent, and its main host is pigs. Infected but undiscovered pigs can carry foot-and-mouth disease virus (FMDV) for a longtime. And, the virus can spread among farms through pig trade.

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