Cross-regional cultural recognition of adolescent voice emotion.

Background: In previous studies, an in-group advantage in emotion recognition has been demonstrated to suggest that individuals are more proficient in identifying emotions within their own culture than in other cultures. However, the existing research focuses mainly on the cross-cultural variations in vocal emotion recognition, with limited attention paid to exploring intracultural differences. Furthermore, there is little research conducted on the ability of adolescents to recognize the emotions conveyed by vocal cues in various cultural settings.

Moderate effectiveness of influenza vaccine in outpatient settings: A test-negative study in Beijing, China, 2023/24 season.

Introduction: The objective of our study was to estimate the influenza vaccine effectiveness for 2023/24 epidemic of co-circulating influenza A(H3N2) and B(Victoria) viruses in Beijing, China.

Methods: The surveillance-based study included all swabbed patients through influenza virological surveillance in Beijing, between October 2023 and March 2024. A Test-Negative Design(TND) was used to estimate influenza vaccine effectiveness(VE) against medically- attended laboratory-confirmed influenza in outpatient settings, also calculated the influenza vaccination rate(IVR).

Neural Modulation Alteration to Positive and Negative Emotions in Depressed Patients: Insights from fMRI Using Positive/Negative Emotion Atlas.

Background: Although it has been noticed that depressed patients show differences in processing emotions, the precise neural modulation mechanisms of positive and negative emotions remain elusive. FMRI is a cutting-edge medical imaging technology renowned for its high spatial resolution and dynamic temporal information, making it particularly suitable for the neural dynamics of depression research.

Methods: To address this gap, our study firstly leveraged fMRI to delineate activated regions associated with positive and negative emotions in healthy individuals, resulting in the creation of the positive emotion atlas (PEA) and the negative emotion atlas (NEA).

[Effect of enhanced silicate minerals weathering on carbon sequestration by plant-soil systems in rice fields].

Successive crop harvest results in soil silicon (Si) loss, which constantly reduces soil available Si. Agricultural measures that can increase the availability of soil Si are in urgent need in agroecosystems. Enhanced weathering of silicate minerals can effectively replenish soil Si, which will promote plant uptake of Si, formation of plant phytolith occluded carbon (PhytOC), and the sequestration of atmospheric CO.

Development and Characterisation of an Immortal Cell Line From Largemouth Bass (Micropterus salmoides) for Viral Studies.

Largemouth bass (Micropterus salmoides), a freshwater fish species, is cultivated widely across China. The industry has been greatly affected by various viral diseases. We generated a new immortal cell line from the fin of M.

Enhanced brain network flexibility by physical exercise in female methamphetamine users.

Unlabelled: Methamphetamine (MA) abuse is increasing worldwide, and evidence indicates that MA causes degraded cognitive functions such as executive function, attention, and flexibility. Recent studies have shown that regular physical exercise can ameliorate the disturbed functions. However, the potential functional network alterations resulting from physical exercise have not been extensively studied in female MA users.

Synthesis and clinical application of new drugs approved by NMPA in 2023.

The National Medical Products Administration (NMPA) in China plays a crucial role in regulating drug approval and ensuring the safety and efficacy of pharmaceutical products. In 2023, the NMPA authorized the approval of 82 novel therapeutic agents, including 48 chemical drugs, 22 biological drugs, 4 vaccines, and 8 traditional Chinese medicines. These approvals span a broad spectrum of therapeutic areas, with a strong focus on oncology, central nervous system disorders, anti-infective treatments, hematology, cardiovascular diseases, ophthalmology, and immunomodulation.

A potential role for the interaction of Wolbachia surface proteins with the Drosophila microtubulin in maintenance of endosymbiosis and affecting spermiogenesis.

Wolbachia, as a widely infected intracellular symbiotic bacterium in Arthropoda, is able to manipulate the reproduction of insect hosts for facilitating their own transmission. Cytoplasmic incompatibility (CI) is the most common phenotype that Wolbachia induced in insect hosts where they resulted in the failure of uninfected egg hatch when fertilized with the sperm derived from Wolbachia-infected males, suggesting that the sperm are modified by Wolbachia during spermatogenesis. Although the molecular mechanisms of CI are beginning to be understood, the effects of Wolbachia on the symbiotic relationship and the proper dynamics of spermatogenesis have not yet been fully investigated.

A cross-sectional study of the association between depression and serum prostate-specific antigen (PSA) among U.S. males: national health and nutrition examination survey (NHANES), 2005-2010.

Background: The association between depression and serum total prostate-specific antigen (PSA) concentrations remains unclear. To explore whether there is a relationship between depression and PSA in American males without prostate cancer (PCa), according to the National Health and Nutrition Examination Survey (NHANES) database.

Methods: Three biennial cycles of survey data from 2005 to 2010 were used in our study.

Bioinformatics- and quantitative proteomics-based identification of gastric adenocarcinoma-related proteins and analysis.

Background: The emergence of immune resistance and a lack of effective therapeutic targets have become significant challenges in immunotherapy, highlighting the urgent need for new molecular markers and treatment targets. Moreover, the significance and mechanisms of PGRN (Progranulin) in gastric cancer remain ambiguous.

Objective: To identify differentially expressed proteins in gastric cancer and elucidate the function and mechanism of PGRN.

A new species of Etrocorema from Yunnan, China, with a redescription of the male of E. hochii (Wu, 1938) (Plecoptera: Perlidae).

A new species of Etrocorema, E. wui sp. nov.

MiR-15a-5p Knockdown up-Regulated ABCB1 Expression and Abated HNSCC Progression via the NF-κB Signaling Pathway.

Background: The high invasion and heterogeneity of head and neck squamous cell carcinoma (HNSCC) commonly leads to poor clinical outcomes. Identification of reliable biomarkers for HNSCC is imperative.

Methods: The targeted gene with the highest mutation was screened out in cBioPortal database, and the interactive microRNAs (miRNAs) were identified by miRNA-mRNA co-expression analysis.

A Natural Eumelanin-Assisted Pullulan/Chitosan Hydrogel for the Management of Diabetic Oral Ulcers.

Existing methods for treating diabetic oral ulcers often fall short in clinical environments due to potential bacterial contamination, oxidative harm, and hindered angiogenesis throughout the healing process. Here, a hydrogel patch (HYG2) have been developed for local in situ application. HYG2 comprises oxidized pullulan, quaternized chitosan, and eumelanin nanoparticles derived from cuttlefish ink.

Impact of easing COVID-19 restrictions on antibiotic usage in Eastern China using wastewater-based epidemiology.

Coronavirus Disease 2019 (COVID-19) emerged in December 2019, prompting the implementation of a "zero-COVID" policy in Mainland China. The easing of this policy in December 2022 led to a surge in COVID cases, which was believed to significantly increase antibiotic usage, potentially due to antibiotic misuse or increased coinfections. Our study aimed to compare antibiotic consumption and patterns before and after this policy adjustment.

Impact mechanism and spatial spillover effect of the digital economy on the high-quality development of undertakings for the aged in China.

Background: Digitalization and population aging have had a profound impact on the development of undertakings for the aged, which brings challenges as well as opportunities for elder care system. This study examines the impact of the digital economy on the high-quality development (HQD) of undertakings for the aged in China.

Methods: Based on the panel data of 31 provinces in mainland China from 2013 to 2021, this study explores the influence mechanism of the HQD of undertakings for the aged driven by the digital economy and its spatial spillover effects.

Global burden of drug use disorders by region and country, 1990-2021.

Background: This study used data from the Global Burden of Disease Study (GBD) database to systematically assess the magnitude of drug use disorders (DUD) burden between 1990 and 2021.

Methods: This study used GBD data to analyze the trends in ASIR, DALYs and other DUD indicators from 1990 to 2021, and compared them among different regions and countries. The Estimated Annual Percentage Change (EAPC) and its 95% Confidence Interval (CI) were calculated to assess the temporal and geographical disparities.

Pyrolysis-Free Synthesis of Synergistic Single-Atom/Nanocluster Electrocatalysts for Hydrogen Evolution.

Constructing catalysts that simultaneously contain single atom/metal nanocluster active sites is a promising strategy to enhance the original catalytic behavior and accelerate the catalysis involving multi-electron reactions or multi-intermediates. Herein, the pyrolysis-free synthetic method is developed to integrate single atoms and nanoclusters towards highly satisfactory catalytic performances for both acidic and alkaline hydrogen electrocatalysis. The controllable pyrolysis-free strategy allows the precise modulation of the active centers, realizing the optimization of the adsorption energy and the regulation of the synergistic active components.

SlVQ15 recruits SlWRKY30IIc to link with jasmonate pathway in regulating tomato defence against root-knot nematodes.

Tomato is one of the most economically important vegetable crops in the world and has been seriously affected by the devastating agricultural pest root-knot nematodes (RKNs). Current understanding of tomato resistance to RKNs is quite limited. VQ motif-containing family proteins are plant-specific regulators; however, whether and how tomato VQs regulate resistance to RKNs is unknown.

Observation of Discrete Charge States of a Coherent Two-Level System in a Superconducting Qubit.

We report observations of discrete charge states of a coherent two-level system (TLS) that is strongly coupled to an offset-charge-sensitive superconducting transmon qubit. We measure an offset charge of 0.072e associated with the two TLS eigenstates, which have a transition frequency of 2.

Methodology comparison of environmental sediment fungal community analysis.

Fungi play important roles in ecosystems. Analyzing fungal communities in environments has long been a challenge due to the large difference in compositions retrieved using different methods or sequencing regions, obscuring the true abundance and species information. Our study aimed to compare and determine more accurate approach for evaluating fungal populations in river sediment.

EGFR-mediated HSP70 phosphorylation facilitates PCNA association with chromatin and DNA replication.

Efficient DNA replication requires highly coordinated programs for the timely recruitment of protein complexes to DNA replication forks. Defects in this process result in replication stress, which in turn activates cell cycle checkpoints, suppresses cell proliferation and induces apoptosis. In response to persistent cell growth signals that speed up DNA replication processes, cells accelerate the recruitment of DNA replication proteins to avoid DNA replication stress.

Accessibility evaluation and multi-scenario optimization of medical services in underdeveloped city driven by multi-source data and latest policies for China.

Equitable and high-quality medical services are more urgent in underdeveloped cities for the higher population ageing and demanding social justice. However, there is little attention paid to the multi-level medical services, particularly regarding the time indicators under the latest policies for underdeveloped cities. The improved efforts were hampered partly by single scenario of location optimization, ignoring the integrated optimization for both road infrastructure and institution location.