Influence of SARS-CoV-2 Infection on the Perioperative Period of Functional Endoscopic Sinus Surgery.

Objective: This study was aimed at exploring the safety and timing of functional endoscopic sinus surgery (FESS) in patients after mild-to-moderate SARS-CoV-2 infection.

Methods: The study group comprised 63 adult inpatients who underwent FESS in our department after mild-to-moderate SARS-CoV-2 infection between December 2022 and February 2023. Sixty adult patients without prior SARS-CoV-2 infection were randomly selected as the control group.

A review: Integration of NIRS and chemometric methods for tea quality control-principles, spectral preprocessing methods, machine learning algorithms, research progress, and future directions.

With the steady rise in tea production, the need for effective tea quality monitoring has become increasingly pressing. Traditional sensory evaluation and wet chemical detection methods are insufficient for real-time tea quality monitoring. As an emerging technology, near infrared spectroscopy (NIRS) offers numerous advantages, such as preserving sample integrity, generating objective results, and enabling rapid, straightforward assessments.

Syn-Net: A Synchronous Frequency-Perception Fusion Network for Breast Tumor Segmentation in Ultrasound Images.

Accurate breast tumor segmentation in ultrasound images is a crucial step in medical diagnosis and locating the tumor region. However, segmentation faces numerous challenges due to the complexity of ultrasound images, similar intensity distributions, variable tumor morphology, and speckle noise. To address these challenges and achieve precise segmentation of breast tumors in complex ultrasound images, we propose a Synchronous Frequency-perception Fusion Network (Syn-Net).

Long-read genome sequencing reveals the sequence characteristics of pear self-incompatibility locus.

The S-RNase-based self-incompatibility locus (S-locus) in Petunia species contains 16-20 F-box genes, which collaboratively function in the recognition and subsequent degradation of non-self S-RNases, while distinguishing them from self S-RNase. However, the number of S-locus F-box genes (SFBBs) physically interacted with non-self S-RNases remains uncertain in Pyrus species. Utilizing Pacbio long-read sequencing, we successfully assembled the genome of pear cultivar 'Yali' (Pyrus bretschneideri), and identified 19 SFBBs from the Pyrus S-locus spanning approximately 1.

Genomic characteristics and phylogenetic analyses of colonization and infection with carbapenem-resistant in multicenter intensive care units: a cohort study.

Unlabelled: Carbapenem-resistant () poses a major threat to global public health. This study aimed to investigate the genomic characteristics and phylogenetic relatedness of colonization and infection with among intensive care unit (ICU) patients. A total of 61 isolates, including 29 non-ICU-acquired and 32 ICU-acquired strains, were collected by active screening and infection culture from 16 ICUs through a multicenter cohort study.

Effect of cultivar and process on the astringency of matcha based on flavonoids-targeted metabolomic analysis.

Astringency is crucial in determining the taste quality of matcha, primarily influenced by flavonoids. However, the specific impact of cultivars and processing techniques on flavonoid composition remains unclear. This study employs quantitative descriptive analysis, multivariate statistical analysis, dose over threshold (Dot) values, and sensory verification to comprehensively analyze changes in flavonoid profiles during the processing of two cultivars (Longjing 43 and Zhongcha 108) and their effects on matcha's astringency.

Retracted: IC-2 Suppresses Proliferation and Induces Apoptosis of Bladder Cancer Cells via the Wnt/β-Catenin Pathway.

This publication has been retracted by the Editor due to the identification of non-original figure images and manuscript content that raise concerns regarding the credibility and originality of the study and the manuscript. Reference: Lingfeng Wu, Shunliang He, Yi He, Xueping Wang, Linfeng Lu. IC-2 Suppresses Proliferation and Induces Apoptosis of Bladder Cancer Cells via the Wnt/ß-Catenin Pathway.

Rapid detection of FAdV-4 by one-tube RPA-CRISPR/Cas12a assay.

Introduction: Fowl adenovirus serotype 4 (FAdV-4) is a highly contagious viral pathogen of global significance that affects various avian species. It primarily infects poultry and wild birds, leading to avian inclusion body hepatitis (IBH) and hepatitis-hydropericardium syndrome (HHS). The development of rapid diagnostic tools for detecting FAdV-4 is crucial for effective disease control and eradication efforts.

Machine Learning-Driven Mass Discovery and High-Throughput Screening of Fluoroether-Based Electrolytes for High-Stability Lithium Metal Batteries.

Developing novel fluoroether electrolytes with high-voltage stability is an effective strategy to improve the performance of lithium metal batteries (LMB). However, the vast chemical space of fluoroether is underexplored due to the absence of effective tools to evaluate the potential used in high-voltage LMB. Herein, a framework was developed in combination of Voting ensemble algorithms and graph convolution neural network (GCNN), allowing the fast assessment of oxidative stability of non-aqueous liquid electrolytes, synthesizability of solvents as well as the solvation ability of them to dissolve lithium salts.

Metagenomic insight into the diffusion signal factor mediated social traits of anammox consortia after starvation.

Biomass starvation is common in biological wastewater treatment. As a social trait of microbial community, how quorum sensing (QS) regulated bacterial trade-off through interactions after starvation remains unclear. This study deciphered the mechanism of anaerobic ammonium oxidation (anammox) consortia in response to starvation, including reducing extracellular electron transfer (EET), adenosine 5'-triphosphate (ATP) content and amino acid metabolism.

Identification of Gene Family and Expression Analysis of Salt Tolerance in .

is one of the typical ecological grass species, characterized by its strong salt tolerance. Hexokinase (HXK) plays a crucial role in plant growth, development, and resistance to abiotic stresses. To understand the function of in the salt tolerance of , this study identified and analyzed the gene family members using the whole-genome data of .

Obesity-induced activation of NADPH oxidase 2 prolongs cardiac repolarization via inhibiting K+ currents.

Obesity is associated with abnormal repolarization manifested by QT interval prolongation, and oxidative stress is an important link between obesity and arrhythmias. However, the underlying electrophysiological and molecular mechanisms remain unclear. The aim of this study is to evaluate the role of obesity in potassium current in ventricular myocytes and the potential mechanism of NADPH oxidase 2 (Nox2).

Analysis of the Changes in Volatile Components During the Processing of Enshi Yulu Tea.

Volatile constituents are critical to the flavor of tea, but the changes in Enshi Yulu tea during the processing have not been clearly understood. Using headspace solid phase microextraction combined with gas chromatography-mass spectrometry (HS-SPME/GC-MS) techniques, we analyze the aroma components of Enshi Yulu tea and changes in them during the processing stages. In total, 242 volatile compounds were identified.

A biosensory μvessel-gravity device for advancing vascular analysis in space medicine.

Studying vascular responses to microgravity (MG) poses significant challenges in space medicine due to the limitations of conventional cell culture and animal models. To address these challenges, we have developed an innovative biosensory μvessel-gravity device that integrates organ-on-a-chip technology, 3D printing, and a 3D clinostat. This device enables cell interaction monitoring and flow shear stress modeling, thereby allowing accurate blood vessel cell sensory to changed mechanical environment.

Transcription factor PbrERF114 is involved in the regulation of ethylene synthesis during pear fruit ripening.

The plant hormone ethylene is indispensable to the ripening of climacteric fruits. Although extensive studies have been conducted on ethylene signaling, the ethylene response factor (ERF)-mediated transcriptional regulation of ethylene biosynthesis in pear fruits remains to be fully elucidated. We here constructed, sequenced, and analyzed transcriptome libraries in ethephon-treated and 1-MCP-treated Cuiguan pear fruits.

The culture and application of circulating tumor cell-derived organoids.

Circulating tumor cells (CTCs), which have the heterogeneity and histological properties of the primary tumor and metastases, are shed from the primary tumor and/or metastatic lesions into the vasculature and initiate metastases at remote sites. In the clinic, CTCs are used extensively in liquid biopsies for early screening, diagnosis, treatment, and prognosis. Current research focuses on using CTC-derived models to study tumor heterogeneity and metastasis, with 3D organoids emerging as a promising tool in cancer research and precision oncology.

A holocellulose air filter with highly efficient formaldehyde adsorption prepared via low temperature pulping and partial dissolving from corn stalks.

Emissions of particulate matter (PM) originating from industrial and agricultural incineration had emerged as a significant public health concern. Furthermore, the considerable annual production of straw remains underutilized, particularly in China. In this study, we proposed a novel approach for holocellulose air filter production from corn stalks via low-temperature anthraquinone pulping, partial dissolving, and high-speed shear-induced regeneration.

3D Bioprinting of Liquid High-Cell-Proportion Bioinks in Liquid Granular Bath.

Embedded 3D bioprinting techniques have emerged as a powerful method to fabricate 3D engineered constructs using low strength bioinks; however, there are challenges in simultaneously satisfying the requirements of high-cell-activity, high-cell-proportion, and low-viscosity bioinks. In particular, the printing capacity of embedded 3D bioprinting is limited as two main challenges: spreading and diffusion, especially for liquid, high-cell-activity bioinks that can facilitate high-cell-proportion. Here, a liquid-in-liquid 3D bioprinting (LL3DBP) strategy is developed, which used a liquid granular bath to prevent the spreading of liquid bioinks during 3D printing, and electrostatic interaction between the liquid bioinks and liquid granular baths is found to effectively prevent the diffusion of liquid bioinks.

Effects of Microbial Proteins on Qingzhuan Tea Sensory Quality during Pile Fermentation.

To determine the effects of microbial proteins on Qingzhuan tea sensory quality during tea pile fermentation, tea leaf metabolomic and microorganism proteomic analyses were performed. In total, 1835 differential metabolites and 443 differentially expressed proteins of the microorganisms were identified. Correlation analysis between metabolomics and proteomics data revealed that the levels of microbial proteins EG II and CBH I cellulase may play important roles in cell wall construction and permeability, which were crucial for the interaction between tea leaves and microorganisms.

Arabinan branches in the RG-I region of citrus pectin aid acid-induced gelation.

Gelation is a critical property of citrus pectin. However, the roles played by neutral sugar side-chains on acid-induced pectin gelation remain poorly understood. Herein, galactan- or/and arabinan-eliminated pectins (P-G, P-A, and P-AG) were used to investigate the effects of side-chains on gelation.

Omnidirectional anisotropic embedded 3D bioprinting.

Anisotropic microstructures resulting from a well-ordered arrangement of filamentous extracellular matrix (ECM) components or cells can be found throughout the human body, including skeletal muscle, corneal stroma, and meniscus, which play a crucial role in carrying out specialized physiological functions. At present, due to the isotropic characteristics of conventional hydrogels, the construction of freeform cell-laden anisotropic structures with high-bioactive hydrogels is still a great challenge. Here, we proposed a method for direct embedded 3D cell-printing of freeform anisotropic structure with shear-oriented bioink (GelMA/PEO).

[Analysis of curative effect of orbital apex syndrome caused by sinus disease].

To compare the efficacy of endoscopic sinus surgery and conservative treatment for orbital apex syndrome caused by sinus lesions. The clinical data of 56 patients with orbital apex syndrome caused by sinus lesions who were admitted to the First Affiliated Hospital of Zhengzhou University from January 2018 to August 2023 were retrospectively analyzed and divided into a surgical group of 21 cases and a conservative group of 35 cases. The clinical features and prognosis of the two groups were compared.

Epithelial Na Channels Function as Extracellular Sensors.

The epithelial Na channel (ENaC) resides on the apical surfaces of specific epithelia in vertebrates and plays a critical role in extracellular fluid homeostasis. Evidence that ENaC senses the external environment emerged well before the molecular identity of the channel was reported three decades ago. This article discusses progress toward elucidating the mechanisms through which specific external factors regulate ENaC function, highlighting insights gained from structural studies of ENaC and related family members.