A real-world analysis of 1,823 hospitalized osteoporotic fractures in Northeast China.

Context: There are limited real-world data evidence assessing the clinical characteristics of hospitalized osteoporotic fractures in China.

Objective: To investigate the clinical characteristics of hospitalized major osteoporotic fractures in Northeast China.

Methods: We identified hospitalized fracture patients aged 50 and over from the First Affiliated Hospital of Jinzhou Medical University between January 1, 2018, and December 31, 2022.

Sulfur Vacancies Limit the Open-Circuit Voltage of SbS Solar Cells.

Antimony sulfide (SbS) is a promising candidate as an absorber layer for single-junction solar cells and the top subcell in tandem solar cells. However, the power conversion efficiency of SbS-based solar cells has remained stagnant over the past decade, largely due to trap-assisted nonradiative recombination. Here we assess the trap-limited conversion efficiency of SbS by investigating nonradiative carrier capture rates for intrinsic point defects using first-principles calculations and Sah-Shockley statistics.

An OMV-Based Nanovaccine as Antigen Presentation Signal Enhancer for Cancer Immunotherapy.

Antigen-presenting cells (APCs) process tumor vaccines and present tumor antigens as the first signals to T cells to activate anti-tumor immunity, which process requires the assistance of co-stimulatory second signals on APCs. The immune checkpoint programmed death ligand 1 (PD-L1) not only mediates the immune escape of tumor cells but also acts as a co-inhibitory second signal on APCs. The serious dysfunction of second signals due to the high expression of PD-L1 on APCs in the tumor body results in the inefficiency of tumor vaccines.

Development of a Deep Learning-Based Model for Pressure Injury Surface Assessment.

Aim: To develop a deep learning-based smart assessment model for pressure injury surface.

Design: Exploratory analysis study.

Methods: Pressure injury images from four Guangzhou hospitals were labelled and used to train a neural network model.

Prevalence and risk factors for type 2 diabetes mellitus in women with gestational diabetes mellitus: a systematic review and meta-analysis.

Introduction: This study aims to explore the risk factors in the progression of gestational diabetes mellitus (GDM) to type 2 diabetes mellitus (T2DM).

Material And Methods: Relevant studies were comprehensively searched from PubMed, Web of Science, Cochrane Library, and Embase up to March 12. Data extraction was performed.

Ultra-Flexible High-Linearity Silicon Nanomembrane Synaptic Transistor Array.

The increasing demand for mobile artificial intelligence applications has elevated edge computing to a prominent research area. Silicon materials, renowned for their excellent electrical properties, are extensively utilized in traditional electronic devices. However, the development of silicon materials for flexible neuromorphic computing devices encounters great challenges.

One-Step Epitaxy of Transition Metal Nitride Nanopillar Arrays with an Oxidation-Tunable Hyperbolic Dispersion.

The controllable synthesis of epitaxial nanopillar arrays is fundamentally important to the development of advanced electrical and optical devices. However, this fascinating growth method has rarely been applied to the bottom-up synthesis of plasmonic nanostructure arrays (PNAs) with many broad, important, and promising applications in optical sensing, nonlinear optics, surface-enhanced spectroscopies, photothermal conversion, photochemistry, etc. Here, a one-step epitaxial approach to single-crystalline NbTiN (NbTiN) nanopillar arrays based on the layer plus island growth mode is demonstrated by strain engineering.

Development and validation of a model based on preoperative dual-layer detector spectral computed tomography 3D VOI-based quantitative parameters to predict high Ki-67 proliferation index in pancreatic ductal adenocarcinoma.

Objective: To develop and validate a model integrating dual-layer detector spectral computed tomography (DLCT) three-dimensional (3D) volume of interest (VOI)-based quantitative parameters and clinical features for predicting Ki-67 proliferation index (PI) in pancreatic ductal adenocarcinoma (PDAC).

Materials And Methods: A total of 162 patients with histopathologically confirmed PDAC who underwent DLCT examination were included and allocated to the training (114) and validation (48) sets. 3D VOI-iodine concentration (IC), 3D VOI-slope of the spectral attenuation curves, and 3D VOI-effective atomic number were obtained from the portal venous phase.

Ultra-highly conductive optoelectronic modulated single-molecule nickel bis(dithiolene) junctions with strong molecule-electrode coupling.

Strong molecule-electrode coupling originating from orbit hybridization between gold and the delocalized molecular wires in single-molecule junctions facilitates facile transport towards smart molecular devices. In this paper, we report ultra-highly conductive single-molecule circuits based on highly delocalized nickel bis(dithiolene) (NiS) molecular junctions using scanning tunneling microscope break junction technique. Single-molecule charge transport measurement of both NiS reveals they exhibits high conductance of 10G and 10G, respectively.

Unraveling the Degradation and Air-Induced Healing Mechanisms of Halide Perovskites under Proton Irradiation.

As exceptional potential candidates for future-generation space photovoltaics, perovskite solar cells (PSCs) have been proven to be radiation-tolerant and recoverable under proton irradiation. Nevertheless, a key point, the influence of the atmosphere, has often been overlooked in ground-based irradiation experiments. Here, the atmosphere-dependent radiation tolerance and healing of perovskite materials under MeV proton irradiation are demonstrated by utilizing in situ electrical characterizations.

A Discovery of Pressure-Induced New Semiconductor Electronic Phase Transitions by DFT Calculations: Introducing a Glimpse of a Novel Semiconductor Family.

This study introduces a discovery of pressure-induced new semiconductor electronic phase transitions. A novel semiconductor family that exhibits pressure-induced nonmonotonic changes in band gaps was found and meets the definition of phase transitions, challenging the traditional understanding of linear and monotonic band gap modification through pressurization. Our findings suggest a complex interplay of atomic spacing and electron orbital contributions under varying pressure conditions, resulting in the variation of band gaps.

Preliminary survey of three mosquito-borne viruses using a self-established multiplex RT-qPCR assay in Chinese blood donors.

Background: Mosquito-borne pathogens pose a significant threat to both human health and blood safety. The primary mosquito-borne viruses that present this threat are Zika virus, Chikungunya virus, and Dengue virus. At present, there are limited efficacious vaccines or therapeutic drugs for the prevention and treatment of these viral infections.

Immunogenicity of an Inactivated COVID-19 Vaccine in People Living with HIV in Guangxi, China: A Prospective Cohort Study.

The inactivated COVID-19 vaccine has demonstrated high efficacy in the general population through extensive clinical and real-world studies. However, its effectiveness in immunocompromised individuals, particularly those living with HIV (PLWH), remains limited. In this study, 20 PLWH and 15 HIV-seronegative individuals were recruited to evaluate the immunogenicity of an inactivated COVID-19 vaccine in PLWH through a prospective cohort study.

Integrating a multi-variable scenario with Attention-LSTM model to forecast long-term coastal beach erosion.

Beach erosion is an adverse impact of climate change and human development activities. Effective beach management necessitates integrating natural and anthropogenic factors to address future erosion trends, while most current prediction models focus only on natural factors, which may provide an incomplete and potentially inaccurate representation of erosion dynamics. This study enhances prediction methods by integrating both natural and anthropogenic factors, thereby enhancing the accuracy and reliability of erosion projections.

Widely Targeted Metabolomics Analysis to Reveal Metabolite of L. in Different Medicinal Parts.

L. is a tradition medical and edible plant. It is rich in many important bioactive components.