Current treatment for male infertility: an umbrella review of systematic reviews and meta-analyses.

This umbrella review aimed to summarize and provide a general evaluation of the effectiveness of current treatments for male infertility and assess the quality of evidence and possible biases. An umbrella review of systematic reviews and meta-analyses available in PubMed, Web of Science, and Scopus, covering studies published up to October 2023, was conducted. Sperm concentration, morphology, and motility were used as endpoints to evaluate the effectiveness of the treatments.

Mast cell degranulation-triggered by SARS-CoV-2 induces tracheal-bronchial epithelial inflammation and injury.

SARS-CoV-2 infection-induced hyper-inflammation is a key pathogenic factor of COVID-19. Our research, along with others', has demonstrated that mast cells (MCs) play a vital role in the initiation of hyper-inflammation caused by SARS-CoV-2. In previous study, we observed that SARS-CoV-2 infection induced the accumulation of MCs in the peri-bronchus and bronchioalveolar-duct junction in humanized mice.

Attractive effects of previous form information on heading estimation from optic flow occur at perceptual stage.

When moving in the environment, optic flow and form (e.g., motion streaks) information generally appear simultaneously.

Vortex radiation from a single emitter in a chiral plasmonic nanocavity.

Manipulating single emitter radiation is essential for quantum information science. Significant progress has been made in enhancing the radiation efficiency and directivity by coupling quantum emitters with microcavities and plasmonic antennas. However, there has been a great challenge to generate complex radiation patterns such as vortex beam from a single emitter.

Use of computed tomography for the diagnosis of surgical sarcopenia: Review of recent research advances.

Sarcopenia, also known as muscle decay, is associated with high morbidity among surgical patients. It is highly correlated with adverse clinical outcomes, such as increased postoperative complications, prolonged hospital stay, and increased mortality. Computed tomography (CT) is one of the main methods for diagnosing sarcopenia, which has the advantages of intuitiveness, rapidity, and accuracy.

A new image encryption algorithm based on the OF-LSTMS and chaotic sequences.

In this paper, a novel image encryption algorithm based on the Once Forward Long Short Term Memory Structure (OF-LSTMS) and the Two-Dimensional Coupled Map Lattice (2DCML) fractional-order chaotic system is proposed. The original image is divided into several image blocks, each of which is input into the OF-LSTMS as a pixel sub-sequence. According to the chaotic sequences generated by the 2DCML fractional-order chaotic system, the parameters of the input gate, output gate and memory unit of the OF-LSTMS are initialized, and the pixel positions are changed at the same time of changing the pixel values, achieving the synchronization of permutation and diffusion operations, which greatly improves the efficiency of image encryption and reduces the time consumption.

IGLL5 is correlated with tumor-infiltrating immune cells in clear cell renal cell carcinoma.

Renal cell carcinomas (RCCs) account for about 90% of renal tumors, and their major histological subtype is ccRCC (clear cell RCC). Increasing evidence has indicated that the tumor microenvironment plays a significant role in the occurrence and development of ccRCC. In this study, we used ESTIMATE and CIBERSORT computational methods to calculate the proportion of immune and stromal components and the rate of TICs (tumor-infiltrating immune cells) in 539 ccRCC samples from The Cancer Genome Atlas database.

Morphological and anatomical characteristics of exserted stigma sterility and the location and function of SlLst (Solanum lycopersicum Long styles) gene in tomato.

Anatomical changes in and hormone roles of the exserted stigma were investigated, and localization and functional analysis of SlLst for the exserted stigma were performed using SLAF-BSA-seq, parental resequencing and overexpression of SlLst in tomato. Tomato accession T431 produces stigmas under relatively high temperatures (> 27 °C, the average temperature in Harbin, China, in June-August), so pollen can rarely reach the stigma properly. This allows the percentage of male sterility exceed 95%, making the use of this accession practical for hybrid seed production.

[Sorption Behaviors of Copper Ions and Tetracycline on Microplastics in Aqueous Solution].

The interaction between microplastics, heavy metals, and antibiotics can lead to combined pollution, which could result in greater environmental damage. The pathway and mechanism of the interaction between microplastics, heavy metals, and antibiotics are the preconditions for evaluating the associated environmental risk; however, these are not well understood. As probe sorbates, the sorption behaviors of copper ions (Cu) and tetracycline (TC) on two microplastics [high density polyethylene (HPDE) and general-purpose polystyrene (GPPS)] in aqueous solution were investigated and the welding theory with relevant experimental results were discussed.

BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.

There is increasing evidence that bone morphogenetic proteins (BMP) are involved in the proliferation and drug tolerance of kidney cancer. However, the molecular mechanism of BMP8A in renal cell proliferation and drug tolerance is not clear. Here we showed that BMP8A was highly expressed in renal cell carcinoma, which suggests a poor prognosis of ccRCC.

Unusual scaling laws for plasmonic nanolasers beyond the diffraction limit.

Plasmonic nanolasers are a new class of amplifiers that generate coherent light well below the diffraction barrier bringing fundamentally new capabilities to biochemical sensing, super-resolution imaging, and on-chip optical communication. However, a debate about whether metals can enhance the performance of lasers has persisted due to the unavoidable fact that metallic absorption intrinsically scales with field confinement. Here, we report plasmonic nanolasers with extremely low thresholds on the order of 10 kW cm at room temperature, which are comparable to those found in modern laser diodes.

Imaging the dark emission of spasers.

Spasers are a new class of laser devices with cavity sizes free from optical diffraction limit. They are an emergent tool for various applications, including biochemical sensing, superresolution imaging, and on-chip optical communication. According to its original definition, a spaser is a coherent surface plasmon amplifier that does not necessarily generate a radiative photon output.

Color image encryption scheme using CML and DNA sequence operations.

In this paper, an encryption algorithm for color images using chaotic system and DNA (Deoxyribonucleic acid) sequence operations is proposed. Three components for the color plain image is employed to construct a matrix, then perform confusion operation on the pixels matrix generated by the spatiotemporal chaos system, i.e.

Stability and synchronization for discrete-time complex-valued neural networks with time-varying delays.

In this paper, the synchronization problem for a class of discrete-time complex-valued neural networks with time-varying delays is investigated. Compared with the previous work, the time delay and parameters are assumed to be time-varying. By separating the real part and imaginary part, the discrete-time model of complex-valued neural networks is derived.

Inhomogeneity of epidemic spreading with entropy-based infected clusters.

Considering the difference in the sizes of the infected clusters in the dynamic complex networks, the normalized entropy based on infected clusters (δ*) is proposed to characterize the inhomogeneity of epidemic spreading. δ* gives information on the variability of the infected clusters in the system. We investigate the variation in the inhomogeneity of the distribution of the epidemic with the absolute velocity v of moving agent, the infection density ρ, and the interaction radius r.

[Prognostic analysis of patients with liver metastases from colorectal cancer treated with different modes of therapy].

Objective: To investigate the potential prognostic factors for patients with liver metastases from colorectal cancer treated with different modes of therapy.

Methods: The clinicopathological data of 300 patients with liver metastases from colorectal cancers were retrospectively reviewed and analyzed.

Results: The median survival of patients with recurrence (MSR) treated with complete and palliative resection of liver metastases and unresectable patients was 48, 19 and 18 months, respectively (P = 0.

[Analysis of prognostic factors in 300 colorectal cancer patients with liver metastases].

Objective: To analyse the clinical characteristics and potential prognostic factors of colorectal cancer patients with liver metastases.

Methods: The clinical and pathological data of 300 colorectal cancer patients with liver metastases were retrospectively reviewed and analyzed.

Results: The median survival time of these patients was 19.

Dynamic analysis of the fractional-order Liu system and its synchronization.

Based on the stability theory of fractional-order systems, the dynamic behaviors of fractional-order Liu system are studied theoretically. Coupling synchronization of two identical fractional-order chaotic systems is also studied and a simple criterion is presented. Numerical simulations show the effectiveness of our methods.

Tracking control and synchronization of four-dimensional hyperchaotic Rossler system.

In this paper we study the problem of the four-dimensional hyperchaotic Rossler system tracking control. A controller based on the reference signal is designed. It is theoretically proved that the controller can make the error converge to zero exponentially.

[Clinical analysis of 67 patients with brain metastases from breast cancer].

Background & Objective: The incidence of brain metastases from breast cancer seems to be increasing with the improvement of systemic control and survival prolongation. This study was to analyze the clinical characteristics, treatment modalities, and prognostic factors of brain metastases from breast cancer.

Methods: The time from primary diagnosis of breast cancer to brain metastases of 67 breast cancer patients were 0-15 years, and the median time was 2.

[Phase II clinical trial on China manufactured recombinant human interleukin-11 derivative in the prevention and treatment of chemotherapy-induced thrombocytopenia].

Objective: This phase II clinical trial was designed to evaluate the efficacy and toxicity of recombinant human interleukin-11 (rhIL-11) derivative manufactured in China in the prevention and treatment of chemotherapy-induced thrombocytopenia in cancer patients.

Methods: A total of 100 cancer patients with chemotherapy-induced thrombocytopenia (< or = 75 x 10(9)/L) were studied by self-cross control. Ninty-one of them received 2 cycles of chemotherapy.

[Clinical analysis of 68 patients with primary gastric lymphoma].

Background & Objectives: Stomach is the most common extranodal involvement site of lymphoma. Treatment patterns for primary gastric lymphoma (PGL) are controversial now. This study was to investigate clinical features, treatment patterns, and prognostic factors of patients with PGL.