Node Attribute-enhanced Community Detection in Complex Networks.

Community detection involves grouping the nodes of a network such that nodes in the same community are more densely connected to each other than to the rest of the network. Previous studies have focused mainly on identifying communities in networks using node connectivity. However, each node in a network may be associated with many attributes.

Haploinsufficiency in the mitochondrial protein CHCHD4 reduces brain injury in a mouse model of neonatal hypoxia-ischemia.

Mitochondria contribute to neonatal hypoxic-ischemic brain injury by releasing potentially toxic proteins into the cytosol. CHCHD4 is a mitochondrial intermembrane space protein that plays a major role in the import of intermembrane proteins and physically interacts with apoptosis-inducing factor (AIF). The purpose of this study was to investigate the impact of CHCHD4 haploinsufficiency on mitochondrial function and brain injury after cerebral hypoxia-ischemia (HI) in neonatal mice.

IL-6 promotes epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through the JAK2/STAT3 signaling pathway.

Long-term peritoneal dialysis (PD) therapy results in functional and structural alteration of the peritoneal membrane, including epithelial-to-mesenchymal transition (EMT). Interleukin 6 (IL-6) is a local pleiotropic cytokine, hypothesized to play an important role in EMT. This study was designed to investigate the role of IL-6 in EMT and peritoneal membrane dysfunction in long-term PD patients by assessing the level of IL-6 in dialysate and exploring the relationship between IL-6, the related signaling pathway JAK2/STAT3, and EMT, using in vitro cellular and molecular techniques.

OXIDATIVE STRESS IN A RAT MODEL OF COTTON SMOKE INHALATION-INDUCED PULMONARY INJURY.

Background: Smoke inhalation injury refers to airway and lung parenchyma injury and general chemical damage caused by inhaling toxic gases and substances. The aim of this study was to explore the oxidative stress mechanism of cotton smoke inhalation-induced pulmonary injury in a rat model.

Materials And Methods: Eighteen male Sprague-Dawley rats were randomly divided into control group, 6 h group, and 24 h group (six rats in each group), which duplicated previous rat cotton smoke-inhalation injury models.

Abnormal subcortical nuclei shapes in patients with type 2 diabetes mellitus.

Objectives: Type 2 diabetes mellitus (T2DM) increases the risk of brain atrophy and dementia. We aimed to elucidate deep grey matter (GM) structural abnormalities and their relationships with T2DM cognitive deficits by combining region of interest (ROI)-based volumetry, voxel-based morphometry (VBM) and shape analysis.

Methods: We recruited 23 T2DM patients and 24 age-matched healthy controls to undergo T1-weighted structural MRI scanning.

KCeIO: a novel potassium cerium(iv) iodate with enhanced visible light driven photocatalytic activity resulting from polar zero dimensional [Ce(IO)] units.

Hydrothermally grown iodate, KCeIO, featuring polar 0D [Ce(IO)] units, has shown the highest visible light driven (VLD) photocatalytic activity in metal iodates reported before. The enhanced VLD photocatalytic property results from a synergistic effect between the narrow band gap and polar 0D [Ce(IO)] units, as confirmed using first principles calculations.

Independent Association between Hyperuricemia and Histopathological Parameters in Chinese Patients with Henöch-Schönlein Purpura Nephritis.

Background: This study aimed to investigate the role of hyperuricemia in the development of histopathological changes in HSPN.

Methods: Clinical and laboratory data pertaining to 139 adult HSPN patients with and without elevated serum uric acid levels were retrospectively evaluated. There was a 14.

Abnormal regional homogeneity and functional connectivity in adjustment disorder of new recruits: a resting-state fMRI study.

Purpose: To explore the regional spontaneous neural activity and functional connectivity alterations of adjustment disorder (AD) in new recruits with in vivo resting-state functional MR (rs-fMRI).

Materials And Methods: Resting-state fMRI was performed in 31 recruits with AD and in 31 control recruits. Regional homogeneity (ReHo) was used to detect the regional synchronizing features of neuronal activations.

Systemic activation of Toll-like receptor 2 suppresses mitochondrial respiration and exacerbates hypoxic-ischemic injury in the developing brain.

Infection and inflammation are known risk factors for neonatal brain injury. Mycoplasma and Gram-positive bacteria, for which Toll-like receptor 2 (TLR2) plays a key role in recognition and inflammatory response, are among the most common pathogens in the perinatal period. Here, we report that systemic activation of TLR2 by Pam3CSK4 (P3C) increases neural tissue loss and demyelination induced by subsequent hypoxia-ischemia (HI) in neonatal mice.

Lead adsorption, anticoagulation and in vivo toxicity studies on the new magnetic nanomaterial FeO@SiO@DMSA as a hemoperfusion adsorbent.

This project aimed to develop and characterize a new nanoadsorbent for hemoperfusion. FeO nanoparticles synthesized by a facile solvothermal method were coated with SO and further modified by DMSA. TEM, XRD, FTIR, XPS and SEM were performed before and after lead adsorption to reveal the general performance and adsorption mechanism.

Hierarchical Context Modeling for Video Event Recognition.

Current video event recognition research remains largely target-centered. For real-world surveillance videos, targetcentered event recognition faces great challenges due to large intra-class target variation, limited image resolution, and poor detection and tracking results. To mitigate these challenges, we introduced a context-augmented video event recognition approach.

Gestational and lactational exposure to di-isobutyl phthalate via diet in maternal mice decreases testosterone levels in male offspring.

Phthalates are a large family of ubiquitous environmental chemicals suspected of being endocrine disruptors, with exposure to these chemicals during prenatal and postnatal development possibly resulting in reproductive disorders. Di-isobutyl phthalate (DiBP) is widely used in consumer and industrial products, and although its exposure in the general population has increased in recent years, the mechanisms behind DiBP-induced reproductive disorders in male offspring remain unclear. Here, pregnant mice were exposed to 0 or 450 mg/kg bw/day DiBP via diet from gestation day (GD) 0 to GD21.

Dispersion relations of refractive indices suitable for KBeBOF crystal deep-ultraviolet applications.

KBeBOF (KBBF) is the only nonlinear optical crystal available to generate deep-ultraviolet (DUV) laser output by direct harmonic generation. High-precision refractive indices, including in the DUV region, were measured, and starting from a double resonance model of polarizability, new dispersion relations of the refractive indices were deduced from the measured data. The predicted phase matching angles for second-harmonic generation down to 165 nm from the new relations agree well with the previous reported values.

Data on taxonomic status and phylogenetic relationship of tits.

The data in this paper are related to the research article entitled "Taxonomic status and phylogenetic relationship of tits based on mitogenomes and nuclear segments" (X.J. Li et al.

Beryllium-Free KBBF Family of Nonlinear-Optical Crystals: AZnBOX (A = Na, K, Rb; X = Cl, Br).

A series of a novel beryllium-free KBBF family of nonlinear-optical materials AZnBOX (A = K, Rb and X = Cl; A = Na, K, Rb and X = Br) were successfully synthesized through molecular engineering design, and single crystals of AZnBOCl (A = K, Rb) were grown by a spontaneous nucleation technique from self-flux systems. As a representative for the halogen KBBF family of crystals, KZnBOCl features the infinite lattice layer [ZnBOCl] made up of BO and ZnOCl anionic groups, and the in-layer BO groups are completely coplanar and well-aligned. Besides, KZnBOCl exhibits high transmittance in the range of 300-2000 nm with a UV-transmission cutoff of around 200 nm according to transmission spectra.

Immune responses in perinatal brain injury.

The perinatal period has often been described as immune deficient. However, it has become clear that immune responses in the neonate following exposure to microbes or as a result of tissue injury may be substantial and play a role in perinatal brain injury. In this article we will review the immune cell composition under normal physiological conditions in the perinatal period, both in the human and rodent.

The Correlation Between Serum Vitamin D Deficiency and Preterm Birth.

BACKGROUND Preterm birth is an important cause of death and developmental disorder in neonates. Vitamin D deficiency has been shown to regulate body inflammatory factor levels that stimulate elevation of uterine contraction hormones, such as prostaglandin, thus causing preterm birth. However, current observations regarding the relationship between vitamin D and preterm birth are inconsistent.

Improvement of immune responses to influenza vaccine (H5N1) by sulfated yeast beta-glucan.

In this study, the adjuvant activity of sulfated glucan from saccharomyces cerevisiae (GSC) was investigated. sGSC had molecular weight of 12.9kDa and degrees of sulfation of 0.

Opportunities for biodiversity gains under the world's largest reforestation programme.

Reforestation is a critical means of addressing the environmental and social problems of deforestation. China's Grain-for-Green Program (GFGP) is the world's largest reforestation scheme. Here we provide the first nationwide assessment of the tree composition of GFGP forests and the first combined ecological and economic study aimed at understanding GFGP's biodiversity implications.

Effect of electrical stimulation on the fate of sulfamethoxazole and tetracycline with their corresponding resistance genes in three-dimensional biofilm-electrode reactors.

Three-dimensional biofilm-electrode reactors (3D-BERs), which possess a large effective area to drive the reductive degradation of contaminants, have recently attracted attention for wastewater treatment. There have been few studies of the potential and risks of the application of this system on the removal of antibiotics. Here four 3D-BERs were designed to initially assess the potential for electrical stimulation to remove sulfamethoxazole (SMX), tetracycline (TC) and chemical oxygen demand, and to study the fate of the corresponding antibiotic resistance genes.

Conversion of Simple Cyclohexanones into Catechols.

A novel I2-catalyzed direct conversion of cyclohexanones to substituted catechols under mild and simple conditions has been described. This novel transformation is remarkable with the multiple oxygenation and dehydrogenative aromatization processes enabled just by using DMSO as the solvent, oxidant, and oxygen source. This metal-free and simple system demonstrates a versatile protocol for the synthesis of highly valuable substituted catechols and therefore streamlines the synthesis and modification of biologically important molecules for drug discovery.

Protective effect of mycophenolate mofetil on residual renal function in peritoneal dialysis patients: An open label feasibility study.

Aim: This study aims to evaluate the safety of mycophenolate mofetil (MMF) and its effect on residual renal function (RRF) during peritoneal dialysis (PD).

Methods: This is a prospective, randomized study comprising 60 PD patients. The patients were assigned either to the MMF group (MMF dosage: 1.