Numerical modeling and parametric analysis of temperature distribution in soil based on water content variation under radio frequency heating for in-situ thermal remediation.

Radio frequency heating (RFH) is recognized as an efficient and economical method for volatilizing organic pollutants from contaminated soils. Although some numerical simulations have been conducted to predict temperature changes during RFH, models that account for effects of water content (WC) variation on dielectric properties and temperature evolution in soil were rarely reported. To address this, a three-dimensional numerical model integrating electromagnetic-thermal conversion, heat transfer, and mass transfer was developed with coupling dynamic changes in WC and corresponding impacts on soil properties.

Contribution assessment and accumulation prediction of heavy metals in wheat grain in a smelting-affected area using machine learning methods.

Due to the diverse controlling factors and their uneven spatial distribution, especially atmospheric deposition from smelters, assessing and predicting the accumulation of heavy metals (HM) in crops across smelting-affected areas becomes challenging. In this study, integrating HM influx from atmospheric deposition, a boosted regression tree model with an average R > 0.8 was obtained to predict accumulation of Pb, As, and Cd in wheat grain across a smelting region.

Time-varying contributions of Fe and Fe to As immobilization under anoxic/oxic conditions: The impacts of biochar and dissolved organic carbon.

Engineering black carbon (e.g. biochar) has been widely found in natural environments due to natural processes and extensive applications in engineering systems, and could influence the geochemical processes of coexisting arsenic (As) and Fe, especially when they are exposed to oxic conditions.

Enhanced Arsenate Immobilization by Kaolinite via Heterogeneous Pathways during Ferrous Iron Oxidation.

Clay minerals are ubiquitous in subsurface environments and have long been recognized as having a limited or negligible impact on the fate of arsenic (As) due to their negatively charged surfaces. Here, we demonstrate the significant role of kaolinite (Kln), a pervasive clay mineral, in enhancing As(V) immobilization during ferrous iron (Fe(II)) oxidation at near-neutral pH. Our results showed that Fe(II) oxidation alone was not capable of immobilizing As(V) at relatively low Fe/As molar ratios (≤2) due to the generation of Fe(III)-As(V) nanocolloids that could still migrate easily as truly dissolved As did.

MINM: Marine intelligent netting monitoring using multi-scattering model and multi-space transformation.

Marine intelligent net tank aquaculture monitoring plays an important role in improving aquaculture efficiency, environmental monitoring efficiency, and environmental safety. The underwater environment has complex light, often with problems such as scattering and absorption, resulting in poor image quality, making it difficult to accurately analyze and judge the aquaculture environment. Improving marine intelligent net tank aquaculture monitoring has the following three advantages: 1) better observation and monitoring of the aquaculture process, timely detection of problems and abnormalities, to protect the benefits of aquaculture and product quality.

Pollution levels and probability risk assessment of potential toxic elements in soil of Pb-Zn smelting areas.

Soil pollution around Pb-Zn smelters has attracted widespread attention around the world. In this study, we compiled a database of eight potentially toxic elements (PTEs) Pb, Zn, Cd, As, Cr, Ni, Cu, and Mn in the soil of Pb-Zn smelting areas by screening the published research papers from 2000 to 2023. The pollution assessment and risk screening of eight PTEs were carried out by geo-accumulation index (I), potential ecological risk index (PERI) and health risk assessment model, and Monte Carlo simulation employed to further evaluate the probabilistic health risks.

Application of machine learning in prediction of Pb adsorption of biochar prepared by tube furnace and fluidized bed.

Data mining by machine learning (ML) has recently come into application in heavy metals purification from wastewater, especially in exploring lead removal by biochar that prepared using tube furnace (TF-C) and fluidized bed (FB-C) pyrolysis methods. In this study, six ML models including Random Forest Regression (RFR), Gradient Boosting Regression (GBR), Support Vector Regression (SVR), Kernel Ridge Regression (KRR), Extreme Gradient Boosting (XGB), and Light Gradient Boosting Machine (LGBM) were employed to predict lead adsorption based on a dataset of 1012 adsorption experiments, comprising 422 TF-C groups from our experiments and 590 FB-C groups from literatures. The XGB model showed superior accuracy and predictive performance for adsorption, achieving R values for TF-C (0.

Fixed-time event-triggered control for multi-agent systems with input delay.

An in-depth study on the fixed-time event-triggered obstacle avoidance consensus control in heterogeneous USV-AUV systems with input delay and uncertain disturbances are conducted in this paper. When initial state of the system fails to achieve consensus, the desired heterogeneous USV-AUV formation can be achieved by fixed-time consensus control, within a fixed predetermined time, regardless of the initial states. Besides, an event-triggered communication strategy among the agents is introduced in the system, significantly reducing communication energy consumption.

Lithium chloride promotes diabetic corneal epithelial wound healing by activating the Wnt/β‑catenin signaling pathway.

Corneal epithelial abnormality is a common manifestation of diabetic keratopathy and leads to delayed epithelial wound healing. The Wnt/β-catenin signaling pathway participates in the development, differentiation and stratification of corneal epithelial cells. The present study compared the expression of Wnt/β-catenin signaling pathway related factors, including Wnt7a, β-catenin, cyclin D1 and phosphorylated (p-) glycogen synthase kinase 3 β (Gsk3b) between normal and diabetic mouse corneas, by reverse transcription-quantitative PCR, western blotting and immunofluorescence staining.

[Pollution Assessment and Source Analysis of Heavy Metals in Atmospheric Deposition in a Lead-zinc Smelting City Based on PMF Model].

To explore the pollution characteristics and sources of heavy metals in atmospheric deposition in a typical lead-zinc smelting city, 511 effective atmospheric deposition samples from 22 points in different functional areas of a city in Henan Province were collected monthly during 2021. The concentrations and spatial-temporal distribution of heavy metals were analyzed. The geo-accumulation index method and health risk assessment model were utilized to evaluate the heavy metal pollution degree.

Screening and characterization of the scFv for chimeric antigen receptor T cells targeting CEA-positive carcinoma.

Introduction: Chimeric antigen receptor T (CAR-T) cell therapy presents a promising treatment option for various cancers, including solid tumors. Carcinoembryonic antigen (CEA) is an attractive target due to its high expression in many tumors, particularly gastrointestinal cancers, while limited expression in normal adult tissues. In our previous clinical study, we reported a 70% disease control rate with no severe side effects using a humanized CEA-targeting CAR-T cell.

Facile construction of irinotecan loaded mesoporous nano-formulation with surface-initiated polymerization to improve stimuli-responsive drug delivery for breast cancer therapy.

This work uses rice husk to fabricate mesoporous silica nanoparticles (D-RMN) for breast cancer therapy. The biocompatible dual-responsive (DAN-RMN) was developed by polymerizing acrylic acid (AA) and n-isopropyl acrylamide (NIPAM) on the DV-RMN surface monomeric ratio to increase drug delivery efficiency after vinyl groups were added to the surface of nanoparticles (DAN-RMN). Various analytical and spectroscopical methods characterized the fabricated nanoparticles.

Evaluation on leachability of heavy metals from tailings: risk factor identification and cumulative influence.

The leachability of heavy metals (HMs) in tailings is significantly affected by multivariate factors associated with environmental conditions. However, the leaching patterns of HMs in molybdenum (Mo) tailings due to environmental change and cumulative influences of multi-leaching factors remain unclear. The leaching behaviors of HMs in Mo tailings were studied through static leaching tests.

Comparison of two different flexible laryngeal airway masks in pediatric ophthalmic surgeries: A retrospective study.

This study aimed to compare the clinical effects of the Medis flexible laryngeal mask airway (FLMA) with those of the Ambu AuraFlex FLMA in pediatric ophthalmic surgery. A total of 80 patients, aged 1 to 5 years, in American Society of Anesthesiologists I-II, weighing ≥10 kg, and without any existing airway difficulties, were enrolled in this study. The patients were randomly divided into Group M (Medis FLMA) and Group A (Ambu AuraFlex FLMA).

CD27 agonism coordinates with CD28 and 4-1BB signal to augment the efficacy of CAR-T cells in colorectal tumor.

Chimeric antigen receptor T cell (CAR-T) is regarded as a promising therapy for malignancies. In our previous clinical trial targeted colorectal tumors, we found that CAR-T cells experienced poor proliferation and persistence in tumor sites. To improve the efficacy of CAR-T cells, we introduced CD27 co-stimulation signal into the established system and found that the CEA28BB27Z CAR-T cells exhibited enhanced proliferation and anti-tumor activity.

Recycled biochar adsorption combined with CaCl washing to increase rice yields and decrease Cd levels in grains and paddy soils: A field study.

Field-scale trials were conducted to remove cadmium (Cd) from paddy soil by using recycled hydroxyapatite modified biochar (HBC) plus low-level CaCl washing. Synergistic reduction efficiencies of total and available Cd in soil (45.6 % and 36.

Reduction of cadmium bioavailability in paddy soil and its accumulation in brown rice by FeCl washing combined with biochar: A field study.

Cadmium (Cd) removal from paddy soil to reduce Cd accumulation in brown rice is essential for agroecology, food safety, and human health. In this study, we demonstrate that ferric chloride (FeCl) washing combined with biochar treatment efficiently remediates Cd-contaminated paddy soil in field trials. Our results showed that 30.

Lenvatinib Combined With a PD-1 Inhibitor as Effective Therapy for Advanced Intrahepatic Cholangiocarcinoma.

Lenvatinib combined with a PD-1 inhibitor has obtained a satisfactory antitumor effect in several solid tumors. However, the efficacy and tumor response of lenvatinib with a PD-1 inhibitor in advanced intrahepatic cholangiocarcinoma still need further exploration. This is a single-arm study for the assessment of the efficacy and tolerability of lenvatinib with a PD-1 inhibitor in intrahepatic cholangiocarcinoma patients who had chemotherapy failure.

Cost-Effectiveness of Posaconazole vs. First-Generation Triazoles for the Prevention of Invasive Fungal Infections Among High-Risk Patients With Hematological Malignancies in China.

Background: Posaconazole is confirmed to be more effective for preventing invasive fungal infections (IFIs) than first-generation triazoles (fluconazole and itraconazole), but its economic value has not been comprehensively evaluated in China. This study compared the cost-effectiveness of these two antifungal prophylaxis regimens in hematological-malignancy patients at high risk for IFIs from the Chinese healthcare perspective.

Methods: A hybrid decision tree and Markov model were built using published data to estimate the total costs and quality-adjusted life-years (QALYs) of antifungal prophylaxis with posaconazole oral suspension and first-generation triazoles.

Fine particulate-bound arsenic and selenium from coal-fired power plants: Formation, removal and bioaccessibility.

The arsenic (As) and selenium (Se) in fine particulate matter (PM) have attracted increasing attentions due to their health effects. However, the emission control of fine particulate-bound arsenic and selenium (fine particulate-bound As/Se) from coal-fired power plants still faces various challenges. Understanding the formation and characteristics of fine particulate-bound As/Se is crucial for developing specific control technologies.

Incidence, risk factors and mortality of invasive pulmonary aspergillosis in patients with influenza: A systematic review and meta-analysis.

Background: An increasing number of cases of invasive pulmonary aspergillosis (IPA) complicating influenza have been described. We performed a meta-analysis to estimate the incidence, risk factors and outcomes of IPA in patients with influenza.

Methods: A systematic search was conducted in the PubMed, EMBASE and Cochrane Library databases from their inception to 31 August 2021 for eligible studies.

Insights into deep decline of As(III) leachability induced by As(III) partial oxidation during lime stabilization of As-Ca sludge.

The enhancing effect of As(III) oxidation on As stabilization by lime is routinely attributed to the lower solubility of Ca arsenates than Ca arsenites. However, this routine explanation is insufficient for the scenario of As(III) partial oxidation, in which Ca arsenites still predominate As leachability due to the relatively high solubility. In this study, an As-Ca sludge with a high As(III) content (96 g/kg, 55% of the As(tot)) was treated by oxidant-lime to clarify the positive effect of As(III) partial oxidation.

Synergistic effect of floatable hydroxyapatite-modified biochar adsorption and low-level CaCl leaching on Cd removal from paddy soil.

The utilization of recycled biochar combined with chemical leaching is an appropriate method to remove cadmium (Cd) from paddy soil. Some Cd-rich soil clay particulates (particulate Cd) are reported to be removed via biochar adsorption and the potential impact of biochar on soil properties need further study. The removal efficiencies and mechanisms of Cd from soil by using floatable hydroxyapatite modified biochar (HBC) combined with CaCl were studied.