Publications by authors named "Wang Kedi"

Article Synopsis
  • PD-1 and PD-L1 inhibitors show potential for treating advanced colorectal cancer (CRC), but their effectiveness and safety need more research.
  • A meta-analysis of nine randomized controlled trials involving 1680 patients showed that while PD-1 inhibitors improve progression-free survival (PFS) and overall survival (OS), PD-L1 inhibitors did not have significant benefits and were linked to more severe adverse events.
  • This study suggests that PD-1 inhibitors are the better choice for patients with advanced CRC due to their efficacy and lower risk of serious side effects compared to PD-L1 inhibitors.
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Co-continuous interlocking lattice structures usually present superior compressive properties and energy absorption characteristics. In this study, co-continuous interlocking polydimethylsiloxane/polylactic acid (PDMS/PLA) lattice composites were designed with different strut diameters, and successfully manufactured by combining the fused deposition modeling (FDM) technique and the infiltration method. This fabrication method can realize the change and control of structure parameters.

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Background: The incidence and mortality of breast cancer in the world remain high. The function and important role of miR-451 and miR-506 in a series of cancers have been proved. The purpose of this research was to explore the clinical diagnosis and prognostic significance of miR-451 and miR-506 expression in breast cancer.

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Background: miR-92b is a carcinogenic miRNA that has great potential as a biomarker for disease prognosis, diagnosis, and treatment in the clinic. It is of great significance to analyse the relationship between miR-92b and the clinicopathological characteristics of cancer patients. This paper aimed to investigate the expression levels and clinical values of miR-92b-3p in breast cancer (BC).

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The bright spot phenomenon during the gas explosion was because of the soot particles of high heat radiation characteristics generated during the explosion process. The formation mechanism of soot and precursor polycyclic aromatic hydrocarbons (PAHs) of the methane explosion was numerically simulated using CHEMKIN-PRO. The methane explosion soot of the CH-air premixed gas explosion experiments with volume concentrations of 8% was collected, and the pore size distribution and surface structure of the soot were analyzed by low-pressure nitrogen gas adsorption (LP-NGA), scanning electron microscopy (SEM), and transmission electron microscopy (TEM).

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The complexity and multiscale structure of coal pores significantly influence the gas diffusion and seepage characteristics of coal. To apply small angle X-ray scattering (SAXS) to study the coal pore structure parameters within the scale of 1-100 nm in the methane adsorption process, the X-ray window was optimized and a gas adsorption chamber was designed to interface with the small angle X-ray scattering platform. The fractal dimension and porosity of Hami coal samples under different methane pressures were studied using the small angle X-ray scattering platform and adsorption chamber.

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We investigated whether an ordinary centrifuge can achieve the standard centrifugal effect required according to specifications for infectious disease screening using the Abbott i2000. Samples were collected and centrifuged following a standard operating procedure (SOP). They were then divided into three groups according to the results of the initial screening tests: a negative group, weak-positive group, and positive group.

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Article Synopsis
  • A study utilized a three-phase partitioning system using dimethyl carbonate (DMC) and sodium citrate (SC) to extract a specific exopolysaccharide (EPS-D) from the fermentation broth of the fungus Phellinus baumii.
  • * The extraction yielded 71.02% EPS-D under optimal conditions, which included a DMC to broth ratio of 0.5:1.0, 19% SC concentration, 30°C temperature, and pH 4.0.
  • * EPS-D showed better antioxidant properties and higher carbohydrate content than another variant (EPS-T) extracted using different solvents, suggesting that DMC could be an effective alternative to t-butanol for partitioning natural biomolecules.*
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Background Epstein-Barr virus (EBV) DNA load monitoring in blood is essential for the diagnosis of EBV-associated diseases. However, the best-suited blood compartment for detection is still under discussion. The aim of this study was to evaluate the diagnostic value of EBV-DNA load in peripheral blood mononuclear cells (PBMC), plasma and whole blood (WB) samples.

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Lactobacilli have been shown to inhibit the proliferation of several types of cancer cells, but the effects of vaginal Lactobacilli on cervical cancer cells have seldom been reported. We incubated Caski cells with supernatants of predominant strains in the vagina and investigated their effects on cell growth and the possible mechanisms. Cell-free supernatants of Lactobacillus crispatus, L.

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Background: With the rapid expansion of infectious syphilis all over the world, optimal procedures for screening syphilis are urgently required. Conventional methods for the diagnosis of syphilis are time- and labor-consuming. We compared automated chemiluminescent micro-particle immunoassay (CLIA) with conventional methods to verify whether CLIA is feasible for syphilis screening.

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Background: Traditional methods for the diagnosis of BV is either with poor sensitivity or poor specificity. Thus, establishing a new method based on the vaginal flora is vital for the diagnosis of BV.

Methods: This article is a retrospective research.

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Background: Serum chemokine CXC Ligand 16 (CXCL16) concentration is associated with atherosclerosis and CXCL16 expression may be influenced by the polymorphism, A181V. We established whether serum CXCL16 concentration or the A181V genotype is more strongly associated with atherosclerotic stroke and its associated risk factor, carotid atherosclerosis.

Methods: PCR-RFLP was used to genotype 244 atherosclerotic stroke patients (AS group), 153 stroke-free controls (patient controls) and 167 healthy controls.

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