Publications by authors named "Wang Junhua"

Background: Cognitive impairment mechanisms in children with preoperative brain tumors are not well understood. This study aimed to determine the correlation between the changes of resting-state functional magnetic resonance imaging (rs-fMRI) and the fourth edition of the Wechsler Intelligence Scale for Children (WISC-IV) in patients with brain tumors before surgery and in healthy controls (HCs).

Methods: rs-fMRI data were acquired using 3-T magnetic resonance imaging (MRI) scanners for 21 patients with pediatric brain tumor and 19 age- and gender-matched HCs.

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  • Hibernation helps animals conserve energy by lowering their metabolic rate and aids survival in tough conditions, but the details of energy adaptation in hibernating ectotherms are still debated.
  • The study found decreased lipid levels and metabolism-related gene expression during hibernation, leading to reduced fat cell sizes and lipid content in the liver, along with lower serum lipid levels and increased glucose.
  • Transcriptomic and lipidomic analyses showed a suppression of lipid metabolism pathways and genes tied to fat breakdown (lipolysis) during hibernation, enhancing our understanding of how these animals adapt their energy use for survival.
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Background: Postoperative pulmonary complications (PPCs) are associated with a higher risk of morbidity and mortality in patients undergoing cardiac surgery. We aimed to investigate the effect of preoperative interventions on PPCs and length of intensive care unit and hospital stay in patients undergoing cardiac surgery.

Methods: A systematic review and meta-analysis was conducted on randomized or quasi-randomized trials by searching PubMed, Medline, ISI Web of Science, Science Direct, Physiotherapy Evidence Database (PEDro), and the Cochrane Library for all available years until December 2023.

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  • China's aging population is leading to an increase in eye diseases, highlighting concerns over visual impairment and blindness.
  • This study explored the connection between asthma and eye conditions like cataracts and glaucoma using data from 19,816 adults in the 2018 China Health and Retirement Longitudinal Survey.
  • Results showed a significant link between asthma and both cataracts (1.36 times more likely) and glaucoma (1.92 times more likely), with specific subgroup populations (women, former smokers, drinkers, and younger adults) identified as at higher risk.
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Non-invasive medical nanofiber technology, characterized by its high specific surface area, biocompatibility, and porosity, holds significant potential in various medical domains, including tissue repair and biosensing. It is increasingly becoming central to healthcare by offering safer and more efficient treatment options for contemporary medicine. Numerous studies have explored non-invasive medical nanofibers in recent years, yet a comprehensive overview of the field remains lacking.

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  • Laser cladding often faces issues like powder plugging and uneven delivery, which impact the final cladding layer's quality, necessitating improvements in powder convergence characteristics.
  • The paper reviews the use of gas-solid two-phase flow technology in studying powder flow, which helps optimize the interaction between air and powder in laser cladding processes.
  • It analyzes advancements in nozzle design and summarizes research findings, offering guidance for future studies to enhance the uniformity and efficiency of powder distribution.
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Background: Ischemia/reperfusion injury (IRI) is a complex pathological process, triggered by the restoration of blood flow following an interrupted blood supply. While restoring the blood flow is the only option to salvage the ischemic tissue, reperfusion after a prolonged period of ischemia initiates IRI, triggering a cascade of inflammatory responses ultimately leading to neutrophil recruitment to the inflamed tissue, where they release neutrophil extracellular traps (NETs). NETs are web-like structures of decondensed chromatin and neutrophilic proteins, including peptidyl-arginine deiminase 2 and 4 (PAD2, PAD4), that, once outside, can citrullinate plasma proteins, irreversibly changing their conformation and potentially their function.

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Background: Sleep regularity has been linked to a risk of arterial stiffness (AS). However, the association between sleep regularity indicators, which reflect 24-hour sleep variability, and AS has not yet been examined.

Methods: We analyzed data from 516 adults, aged 40-65 years (the median age of 51 years), from the 'Follow-up Study of Sleep Characteristics and Chronic Diseases in the Middle-aged and Elderly Population in Guizhou Province'.

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  • CA125 is a key biomarker for diagnosing ovarian cancer, and the paper discusses a new ultrasensitive immunosensor designed to detect it using advanced materials.
  • The sensor combines TiCT-MXene and amino-functionalized carbon nanotubes to enhance electrochemical signals and stability, making it highly effective for CA125 detection.
  • Testing showed that the immunosensor reliably detects CA125 levels in a wide range and performs well with clinical serum samples, indicating its potential for improving ovarian cancer diagnosis and monitoring.
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Introduction: Continuous extracorporeal perfusion (ECP), or machine perfusion, holds promise for prolonged skeletal muscle preservation in limb ischemia-reperfusion injury. This study aimed to extend the amputation-to-replantation time window from currently 6 hours to 33 hours using a 24-hour ECP approach.

Materials And Methods: Six large white pigs underwent surgical forelimb amputation under general anesthesia.

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  • - A new term, small and vulnerable newborns (SVN), is proposed to collectively assess preterm births, small for gestational age (SGA), and low birth weight (LBW) in identifying high-risk newborns.
  • - The incidence of high-risk newborns has increased from 9.82% to 10.96% between 2013 and 2022 among a study of over 2 million newborns, highlighting the importance of the SVN definition which incorporates various risk factors like maternal age, first-time motherhood, and multiple births.
  • - Public health practices should adopt this new framework to better identify and address high-risk cases, particularly focusing on preventing issues related to multiple births and the implications for first
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  • Socioeconomic development has led to more older pregnancies and women having multiple children, which poses risks to both mothers and infants.
  • The report highlights that as the number of previous pregnancies (parities) increases, there are more older mothers and less women with higher education, while these women are also more likely to experience preterm births and larger babies.
  • Understanding pregnancy characteristics based on the number of past pregnancies can help create targeted public health strategies to improve pregnancy outcomes.*
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Tumour-host immune interactions lead to complex changes in the tumour microenvironment (TME), impacting progression, metastasis and response to therapy. While it is clear that cancer cells can have the capacity to alter immune landscapes, our understanding of this process is incomplete. Herein we show that endocytic trafficking at the plasma membrane, mediated by the small GTPase ARF6, enables melanoma cells to impose an immunosuppressive TME that accelerates tumour development.

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Herein, we firstly develop porous organic cage (POC) as an efficient platform for highly effective radioactive iodine capture under industrial operating conditions (typically ≥150 °C), ≤150 ppmv of I). Due to the highly dispersed and readily accessible binding sites as well as sufficient accommodating space, the constructed NKPOC-DT-(I) (NKPOC=Nankai porous organic cage) demonstrates a record-high I uptake capacity of 48.35 wt % and extraordinary adsorption capacity of unit ionic site (~1.

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Flexible electronics is an emerging and cutting-edge technology which is considered as the building blocks of the next generation micro-nano electronics. Flexible electronics integrate both active and passive functions in devices, driving rapid developments in healthcare, the Internet of Things (IoT), and industrial fields. Among them, flexible temperature sensors, which can be directly attached to human skin or curved surfaces of objects for continuous and stable temperature measurement, have attracted much attention for applications in disease prediction, health monitoring, robotic signal sensing, and curved surface temperature measurement.

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The morphology size of laser cladding is a crucial parameter that significantly impacts the quality and performance of the cladding layer. This study proposes a predictive model for the cladding morphology size based on the Least Squares Support Vector Regression (LSSVR) and the Crowned Porcupine Optimization (CPO) algorithm. Specifically, the proposed model takes three key parameters as inputs: laser power, scanning speed, and powder feeding rate, with the width and height of the cladding layer as outputs.

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Laser-arc hybrid additive manufacturing (LAHAM) holds substantial potential in industrial applications, yet ensuring dimensional accuracy remains a major challenge. Accurate prediction and effective control of the geometrical dimensions of the deposited layers are crucial for achieving this accuracy. The width and height of the deposited layers, key indicators of geometric dimensions, directly affect the forming precision.

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The semantic segmentation of the 3D operating environment represents the key to intelligent mining shovels' autonomous digging and loading operation. However, the complexity of the operating environment of intelligent mining shovels presents challenges, including the variety of scene targets and the uneven number of samples. This results in low accuracy of 3D semantic segmentation and reduces the autonomous operation accuracy of the intelligent mine shovels.

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Objective To investigate the expression levels of lncRNA H19 in ulcerative colitis (UC) patients and its role in UC. Methods Colonic mucosa and serum samples were collected from 25 UC patients and 25 healthy individuals at the General Hospital of Xizang Military Region. The expression levels of lncRNA H19 were detected, and the receiver operating characteristic (ROC) curve analysis was performed using serum samples.

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A novel method is introduced for extracting and enriching Cd(II) and Pb(II) from edible oils using glutathione disulfide (GSSG) as both an extractant and a phase-separation agent. The ions in the oils were initially extracted into an aqueous solution containing GSSG. After mixing the solution with acetonitrile at the appropriate volume ratio, a new phase formed, resulting in enrichment of the analytes.

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Interactions between positively charged amino-modified (APS) and negatively charged bare (BPS) polystyrene nanoplastics may cause heteroaggregation in aquatic environments. This study investigated the effects of particle concentration ratio, solution chemistry [electrolytes, pH, and natural organic matter (NOM)], and interaction sequence on their heteroaggregation kinetics. In the absence of electrolytes and NOM, the APS/BPS ratio for attaining maximum heteroaggregation rate (k) increased from APS/BPS= 3/7 to APS/BPS= 1/1 as pH increased from 4 to 10, indicating that electrostatic interactions dominated heteroaggregation.

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  • * Key findings demonstrate that black carbon, organic matter (OM), nitrate, ammonium, chloride, and sulfate all increase CVD risks, with OM and chloride identified as the most significant contributors.
  • * Additionally, the research suggests that the link between OM and CVD is partially mediated by metabolic syndrome, indicating a small contribution (1.3%) of metabolic pathways in this association.
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In this paper, a temperature measurement system with NTC (Negative Temperature Coefficient) thermistors was designed. An MCU (Micro Control Unit) primarily operates by converting the voltage value collected by an ADC (Analog-to-Digital Converter) into the resistance value. The temperature value is then calculated, and a DAC (Digital-to-Analog Converter) outputs a current of 4 to 20 mA that is linearly related to the temperature value.

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The self-assembled carbon nitride quantum dots (CNQDs) has been largely advanced owing to the structure-relative photocatalytic activities, especially its electronic structure, which can be regulated by defects, functional groups, and doping. However, there are still issues such as wide band gaps for the assembles and severe recombination of photoinduced charges. Herein, we demonstrate the self-assembly of CNQDs into fusiform hollow superstructures (CNFHs), induced by hydrogen bonding between the terminal functional groups (-OH, -COOH, and -NH).

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