Publications by authors named "Wang Jinjin"

Top-view systems for lameness detection have advantages such as easy installation and minimal impact on farm work. However, the unclear lameness motion characteristics of the back result in lower recognition accuracy for these systems. Therefore, we analysed the compensatory behaviour of cows based on top-view walking videos, extracted compensatory motion features (CMFs), and constructed a model for recognising lameness in cows.

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Background: Evidence on the association of dynamic change in frailty index (FI) with risk of all-cause mortality in the older Chinese population is limited. This study aimed to explore the association of 3-year change in FI with risk of all-cause mortality in an older Chinese population.

Methods: We analyzed the data of 4969 participants from the Chinese Longitudinal Healthy Longevity Survey.

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In order to study the optimal use of Lactobacillus plantarum in sea cucumber (Apostichopus japonicus), 49 days feeding trial was conducted to determine the influence of immersion bathing in different concentrations of Lactobacillus plantarum CLY-05 on body weight gain rate and non-specific immune activities. The potential effect of CLY-05 on gut microbiota was also analyzed during the immersion bathing at the optimum concentration. The results showed that the body weight growth rate of all bathing groups was higher than that of control.

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Exogenous spatial attention attenuates audiovisual integration (AVI). Previous studies on the effects of exogenous spatial attention on AVI have focused on the inhibition of return (IOR) effect induced by visual cues and the facilitation effect induced by auditory cues, but the differences between the effects of exogenous spatial attention (induced by visual and auditory cues) on AVI remain unclear. The present study used the exogenous spatial cue-target paradigm and manipulated cue stimulus modality (visual cue, auditory cue) in two experiments (Experiment 1: facilitation effect; Experiment 2: IOR effect) to examine the effects of exogenous spatial attention (evoked by cues in different modalities) on AVI.

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Background: Behavioral and psychological symptoms of dementia (BPSD), as neuropsychiatric manifestations within dementia, constitute core features of dementia. However, there remains a gap in understanding the recognition of BPSD in China. Our current study was to explore the clinical awareness and treatment approaches for BPSD in China, focusing especially on the perspectives of neurologists and psychiatrists.

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Carbazomycins (-) are a subgroup of carbazole derivatives that contain oxygen at the C3 and C4 positions and an unusual asymmetric substitution pattern. Several of these compounds exhibit antifungal and antioxidant activities. To date, no systematic biosynthetic studies have been conducted on carbazomycins.

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Mining activities have led to significant rare earth elements (REEs) contamination and ecotoxicological risks in aquatic systems. However, the concentration, speciation, and primary controlling factors of REEs in aquatic systems in southwest China have remained unclear. This study investigated the water geochemistry, concentration, speciation, fractionation patterns, and anomalies of REEs in the surface water, shallow groundwater, and deep groundwater within a mining-impacted catchment area in southwest China across different seasons.

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  • Dihydrolipoamide S-acetyltransferase (DLAT) is a critical subunit of the pyruvate dehydrogenase complex, influencing both glycolysis and the tricarboxylic acid cycle, but its role in tumor development is not fully understood.
  • The study utilized various computational methods to analyze DLAT's expression, genetic variations, immune interactions, and responses to treatment across different cancers, particularly focusing on glioma cells.
  • Results showed that increased DLAT expression is linked to poor patient survival, affects immune cell dynamics, and contributes to tumor cell resilience against treatments, making it a potential biomarker for diagnosis and immunotherapy in cancer.
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Introduction: Decreased periodontal ligament stem cells (PDLSCs) stemness is a key factor in age-related alveolar bone loss. Endoplasmic reticulum (ER) stress is closely related to age-related diseases and the mesenchymal stem cell (MSC) stemness. However, the role of ER stress in regulating the stemness of senescent PDLSCs and its potential mechanism remain unclear.

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  • This study investigates cellular senescence and its impact on aging and disease, focusing on the roles of different cell types, particularly in the context of liver injury and repair.
  • Researchers created a set of genetic tools to trace and manipulate p16 cell types in vivo, revealing that macrophages and endothelial cells (ECs) have unique roles and outcomes in liver fibrosis and regeneration.
  • Findings show that removing senescent macrophages helps reduce liver damage, while clearing senescent ECs worsens it; additionally, enhancing EC function through a specific gene reduces fibrosis, suggesting potential strategies for targeted therapies.
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Currently, research on Ag nanoparticles (AgNPs) predominantly focuses on UV/visible photodetection and UV emission, seemingly overlooking the significance of Ag in enhancing deep ultraviolet photon detection. In this work, (InGa)O thin films were fabricated by plasma-enhanced chemical vapor deposition. Due to the unique photoabsorbance characteristic and better interaction with photons of small-sized AgNPs, they effectively suppress the UVB absorbance caused by energy band engineering in the (InGa)O thin film while enhancing photoabsorbance in UVC due to the surface plasmon effect.

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  • Human adenovirus (HAdV) is a significant cause of acute respiratory infections in children in China, particularly HAdV-4, which has resulted in deaths but has been poorly studied.
  • From 2017 to 2020, researchers analyzed respiratory samples from 2,847 children hospitalized with acute respiratory infections, finding that HAdV-4 was present in 0.39% of samples, mainly causing fever and cough, with some severe cases requiring intensive care.
  • The genetic study revealed that the strains of HAdV-4 from this research are closely related to others in China, showing some mutations in capsid proteins but no signs of new recombination, indicating stability in the virus's genetic makeup.
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  • A double network hydrogel, FeO@LH, was developed from lignosulfonate and polyacrylamide with embedded FeO nanoparticles to effectively remove lead (Pb) from contaminated soil.
  • The hydrogel showed a high adsorption capacity for Pb(II) at 143.11 mg/g and achieved a 22.3% removal efficiency through various mechanisms like electrostatic adsorption and cation exchange.
  • FeO@LH not only reduces Pb but also lowers cadmium (Cd) and arsenic (As) levels, while improving soil quality indicators, and maintains over 75% recovery after 90 days of use, proving its biosafety through toxicity tests on zebrafish larvae.
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Cadmium (Cd) removal from soil is crucial as Cd enters the food chain and affect food safety, thus impose severe threaten to human health. We developed PPC@PC-Fe, a dual-functional core-shell sphere for efficient soil Cd reduction. The shell (PPC) was composed of encapsulated citric acid (CA) in a polylactic acid (PLA) and polyethylene glycol (PEG) network, which endows a function of activating Cd; and the core (PC-Fe) consisted of a polyacrylic acid/carboxymethyl chitosan (PAA/CMC) hydrogel with FeO nanoparticles to adsorb adjacent activated Cd.

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Withering is the first and key process that influences tea quality, with light quality being a key regulatory factor. However, effects of withering light quality (WLQ) on transformation and formation pathways of tea aroma and volatile metabolites (VMs) remain unclear. In the present study, four WLQs were set up to investigate their effects on tea aroma and VMs.

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Aim: The degradation of the cartilage endplate (CEP) plays a critical role in the initiation and progression of intervertebral disc degeneration (IVDD), a disease closely associated with inflammation and oxidative stress. Naringin (NGN), a flavonoid compound derived from citrus fruits, has been shown to exhibit significant anti-inflammatory and antioxidant properties. This suggests a promising avenue for NGN's application in IVDD therapy.

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  • Immune evasion by tumors limits the effectiveness of immunotherapy, with ALDH1A1 identified as a crucial gene for cancer prognosis and tumor growth inhibition in preliminary studies.
  • Research indicates that targeting ALDH1A1 can suppress tumors and promote immune activity, with ZBTB7B identified as a key transcription factor influenced by ALDH1A1 that regulates glycolysis.
  • Combining ALDH1A1 and ZBTB7B targeting with immune checkpoint inhibitors shows promising potential to enhance cancer treatment effectiveness and reduce tumor immune escape.
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Passive imaging for mid-wave infrared (MWIR) is resistant to atmospheric pollutants, guaranteeing image clarity and accuracy. Arrayed photodetectors can simultaneously perform radiation sensing to improve efficiency. Room temperature van der Waals (vdWs) photodetectors without lattice matching have evolved rapidly with optimized stacking methods, primarily for single-pixel devices.

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species usually inhabit intertidal zones and deep-sea sediments. Their accurate identification has proven to be challenging. Here, we present the complete mitochondrial genome of one Montagu 1808 specimen collected from China.

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This study develops a series of NBI-based acidochromic AIEgens engineered for ultra-wide acidochromic scope in self-reporting soft actuators, establishing the relationship between the photophysical properties and structural configurations of the AIEgens, further investigating their acidochromic behavior and fabricating acidity monitoring chips. The acidochromic behaviors were thoroughly investigated, and high-precision acidity monitoring chips were fabricated. We confirmed the protonation order of nitrogen atoms within the molecules and elucidated the acidochromic mechanisms through DFT and H NMR analyses.

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  • Researchers studied how working memory impacts the ability to ignore distractions during visual tasks, focusing on individuals with substance use disorder (SUD) and their cognitive control challenges.
  • The study utilized a dual-task approach, where participants memorized color words while performing a search task, examining the effects of congruent auditory information during memory encoding.
  • Results showed that the control group had a faster response when the memory matched distractors, while both groups benefited from audiovisual cues, with SUD patients showing delayed facilitation, highlighting differences in distraction processing strategies.
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Messenger RNA (mRNA) is an emerging class of therapeutic agents for treating a wide range of diseases. However, due to the instability and low cell transfection rate of naked mRNA, the expression of delivered mRNA in target cells or tissues in vivo requires delivery strategies. Biomimetic vectors hold advantages such as high biocompatibility, tissue specific targeting ability and efficient delivery mechanisms, potentially overcoming challenges faced by other delivery vectors.

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  • 1. 1,4-diaminobutane is important in producing various industrial products, leading to interest in using microbes for its production to address economic and environmental issues.
  • 2. The study investigates the effects of cofactors pyridoxal phosphate (PLP) and NADPH on the synthesis process, noting the need for both in higher yields.
  • 3. By optimizing gene expression related to PLP and NADPH, the researchers achieved a 79% increase in 1,4-diaminobutane yield, reaching 272 mg/L·DCW in a recombinant strain.
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  • - This study investigates the non-volatile metabolites (NVMs) in Round Green Tea (RGT) during its processing, revealing that fixation and pan-frying are crucial steps that significantly affect these compounds.
  • - A total of 216 NVMs were characterized, and 23 key metabolites were identified, focusing on amino acids and flavonoids as important pathways influencing the taste and color of RGT.
  • - The research found that moderate pan-frying resulted in an optimal combination of a tight shape, bright color, and balanced flavor, while reducing undesirable bitter and astringent NVMs, thus offering insights for improving RGT quality.
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