The Development of Prenatal Muscle Satellite Cells (MuSCs) and Their Epigenetic Modifications During Skeletal Muscle Development in Yak Fetus.

To investigate prenatal muscle satellite cell (MuSC) development and the associated epigenetic modifications in yak. Here, we conducted morphological and protein co-localization analyses of fetal longissimus dorsi muscle at various developmental stages using histology and immunofluorescence staining methods. Our study observed that primary muscle fibers began forming at 40 days of gestation, fully developed by 11 weeks, and secondary muscle fibers were predominantly formed by around 105 days.

The effect of intraoperative radiotherapy in musculoskeletal malignancy: A population study from US SEER database.

The aim of our study was to explore the effect of IORT on survival outcome of patients with musculoskeletal malignancy. The prognostic factors of patients with IORT treatment were also identified in this study. The retrospective analysis was conducted based on the Surveillance, Epidemiology, and End Results (SEER) database spanning from 2000 to 2020.

Inhibition of Chitinase-3-like Protein 1 Reduced Epithelial-Mesenchymal Transition and Vascular Epithelial Cadherin Expression in Oesophageal Squamous Cell Carcinoma.

Background: Oesophageal cancer (EC) is one of the common malignant tumors, and the prognosis of patients is poor. Further exploration of EC pathogenesis remains warranted.

Objective: The relationship between vascular epithelial cadherin (VE-cadherin) and chitinase-3-like protein 1 (CHI3L1) in EC is currently unknown.

CD93 aggravates cell proliferation, angiogenesis and immune escape in osteosarcoma through triggering the PI3K/AKT pathway.

Background: Osteosarcoma is the most familiar primary malignant tumor occurred in bone in young people and is featured by complicated genetic changes. CD93 has been affirmed to exhibit the facilitative roles in multiple cancers.

Methods: But, the detailed impacts and related regulatory pathway of CD93 in osteosarcoma progression maintain unclear.

Identification of candidate genes related to hybrid sterility by genomic structural variation and transcriptome analyses in cattle-yak.

Hybrids between closely related but genetically incompatible species are often inviable or sterile. Cattle-yak, an interspecific hybrid of yak and cattle, exhibits male-specific sterility, which limits the fixation of its desired traits and prevents genetic improvement in yak through crossbreeding. Transcriptome profiles of testicular tissues have been generated in cattle, yak, and cattle-yak; however, the genetic variations underlying differential gene expression associated with hybrid sterility have yet to be elucidated.

Evaluation of landslides susceptibility in Southeastern Tibet considering seismic sensitivity.

Southeastern Tibet features a complex geological environment and a high incidence of earthquakes. Earthquake-induced chain disasters pose a great threat to engineering construction and public safety in this area, and landslides are among the most frequent postearthquake disasters. To investigate the impact of earthquakes on landslides, this study constructed a comprehensive database for landslide susceptibility analysis based on various factors, including elevation, slope, slope direction, distances from roads and rivers, proximity to faults, land use patterns, rainfall patterns, and seismic parameters.

METTL3-mediated m6A modification of LINC00520 confers glycolysis and chemoresistance in osteosarcoma via suppressing ubiquitination of ENO1.

Chemoresistance remains the main obstacle limiting the treatment of osteosarcoma, seriously affecting the prognosis of adolescent patients with osteosarcoma. Recently, long non-coding RNAs (lncRNAs) were reported to be involved in chemoresistance, while the mechanisms of lncRNAs underlying osteosarcoma resistance to chemotherapy remain elusive. Here, LINC00520 was identified as a novel cisplatin resistance-related lncRNA in osteosarcoma, and its high expression was associated with poor prognosis of osteosarcoma patients.

Enhancement of ammonia synthesis via electrocatalytic reduction of low-concentration nitrate using co-doped MIL-101(Fe) nanostructured catalysts.

In the domain of electrocatalytic NO reduction (NORR) for the treatment of low-concentration nitrate-containing domestic or industrial wastewater, the conversion of NO into NH holds significant promise for resource recovery. Nevertheless, the central challenge in this field revolves around the development of catalysts exhibiting both high catalytic activity and selectivity. To tackle this challenge, we design a two-step hydrothermal combine with carbonization process to fabricate a cobalt-doped Fe-based MOF (MIL-101) catalyst at 800 °C temperatures.

Developing Z-scheme BiMoO@α-MnO beaded core-shell heterostructure in photoelectrocatalytic treatment of organic wastewater.

Photoelectrocatalysis (PEC) oxidation technology with the combination of electrocatalysis and photocatalysis is an ideal candidate for treatment of dyeing wastewater containing multifarious intractable organic compounds with high chroma. Constructing high-quality heterojunction photoelectrodes can effectively suppress the recombination of photo-generated carriers, thereby achieving efficient removal of pollution. Herein, a beaded BiMoO@α-MnO core-shell architecture with tunable hetero-interface was prepared by simple hydrothermal-solvothermal process.

Investigation into the role of H2-Ab1 in vascular remodeling in pulmonary arterial hypertension via Bioinformatics.

Background: Pulmonary arterial hypertension (PAH) is a progressive disease of vascular remodeling characterized by persistent pulmonary arterial pressure elevation, which can lead to right heart failure and premature death. Given the complex pathogenesis and poor prognosis of PAH, the identification and investigation of biomarkers become increasingly critical for advancing further understanding of the disease.

Methods: PAH-related datasets, GSE49114, GSE180169 and GSE154959, were downloaded from the publicly available GEO database.

Comparative outcomes of video-assisted thoracoscopic surgery versus open surgery for bronchogenic cysts in adults: a retrospective cohort study.

Background: Open thoracotomy has been the traditional surgical approach for patients with bronchogenic cysts (BCs). This study aimed to evaluate the safety and efficacy of video-assisted thoracoscopic surgery (VATS) compared to open surgery for the treatment of BCs in adults.

Methods: This single-institution, retrospective cohort study included 117 consecutive adult patients who underwent VATS (group A) or open surgery (group B) for BC resection between February 2019 and January 2023.

Cerium oxide /Co-Co Prussian blue analogue composite catalyst for enhanced peroxymonosulfate activation for effective removal of tetracycline hydrochloride from water.

In this paper, a novel CeO/Co[Co(CN)] (CeO/PBA) composite was prepared with co-precipitation and utilized to activate peroxymonosulfate (PMS) to eliminate tetracycline hydrochloride (TCH). Catalyst screening showed that the composite with a CeO:PBA mass ratio of 1:5 (namely, 0.2-CeO/PBA) had the best performance.

Single atom nanozyme sensing platform for simultaneous rapid detection of multiple bisphenols.

Bisphenol compounds (BPA, BPS, BPAF, etc.) are one class of the most important and widespread pollutants that poses severe threat to human health and the ecological environment. Because of the presence of multiple bisphenols in environmental and food samples, it is urgent and challenging to develop a rapid and cheap technique for simultaneously detecting BPA and its analogues.

ZnSnO@Ti ceramic film anode preparation by microarc oxidation for 2e WOR degradation of unsymmetrical dimethylhydrazine (UDMH).

The main challenge facing the anodic electro-Fenton through the 2e water oxidation reaction (WOR) for toxics degradation lies in the electrode's stability, because the anodic oxygen evolution (OER) generated O will inevitably exfoliate the electro-active components loaded on the electrode substrate. To address this point, two aspects need attention: 1) Identifying a catalyst that exhibits both excellent electrocatalytic activity and selectivity can improve the faradaic efficiency of hydrogen peroxide (HO); 2) Employing novel methods for fabricating highly stable electrodes, where active sites can be firmly coated. Consequently, this study utilized microarc oxidation (MAO) to prepare a ceramic film electrode ZnSnO@Ti at 300 V.

Construction of an oxidative phosphorylation-related gene signature for predicting prognosis and identifying immune infiltration in osteosarcoma.

Background: Osteosarcoma is a prevalent malignant tumor that originates from mesenchymal tissue. It typically affects children and adolescents. Although it is known that the growth of osteosarcoma relies on oxidative phosphorylation for energy production, limited attention has been paid to exploring the potential of oxidative phosphorylation-related genes in predicting the prognosis of individuals suffering from osteosarcoma.

Integrating tertiary lymphoid structure-associated genes into computational models to evaluate prognostication and immune infiltration in pancreatic cancer.

Pancreatic ductal adenocarcinoma (PDAC) is characterized by poor response to all therapeutic modalities and dismal prognosis. The presence of tertiary lymphoid structures (TLSs) in various solid cancers is of crucial prognostic significance, highlighting the intricate interplay between the tumor microenvironment and immune cells aggregation. However, the extent to which TLSs and immune status affect PDAC prognosis remains incompletely understood.

Constructing core-shell structured CoO-MnWO composite photoelectrode with superior PEC water purification performance.

Semiconductor photoelectrocatalytic (PEC) technology is one of the most effective methods for removing organic pollutants from wastewater in advanced oxidation processes(AOPs). The selection of suitable semiconductor materials as photoanodes is a crucial factor for achieving superior PEC performance. Here, a core-shell structured CoO-MnWO architecture is created by enveloping MnWO nanoparticles onto the surface of CoO nanowires through a two-step hydrothermal process.

Oxygen vacancy based WO/SnO promote electrochemical HO accumulation by two-electron water oxidation reaction and toxic uniform dimethylhydrazine degradation.

The key to constructing an anodic electro-Fenton system hinges on two pivotal criteria: enhancing the catalyst activity and selectivity in water oxidation reaction (WOR), while simultaneously inhibiting the decomposition of hydrogen peroxide (HO) which is on-site electrosynthesized at the anode. To address the issues, we synthesized novel WO/SnO electrocatalysts, enriched with oxygen vacancies, capitalize on the combined activity and selectivity advantages of both WO and SnO for the two-electron pathway electrocatalytic production of HO. Moreover, the introduction of oxygen vacancies plays a critical role in impeding the decomposition of HO.

Transcriptomics and metabolomics of blood, urine and ovarian follicular fluid of yak at induced estrus stage.

To gain a deeper understanding of the metabolic differences within and outside the body, as well as changes in transcription levels following estrus in yaks, we conducted transcriptome and metabolome analyses on female yaks in both estrus and non-estrus states. The metabolome analysis identified 114, 13, and 91 distinct metabolites in urine, blood, and follicular fluid, respectively. The Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis highlighted an enrichment of pathways related to amino acid and lipid metabolism across all three body fluids.

Small Channels Assembled by Multilayer ZIF-8 in Nanocomposite Membranes for Filtration of Ofloxacin in Water.

Metal-organic framework (MOF)-based hybrid membranes still face many unsolved difficulties in the field of liquid separation, with a reliable production technique standing out, in particular, for the water-stable MOF membranes. In this study, zeolitic imidazolate framework-8 (ZIF-8) with acceptable water stability, favorable polymer affinity, and high selectivity was meticulously grafted on commercial poly(vinylidene fluoride) (PVDF) via substrate carboxylation-assisted etching and then overlaid onto PVDF to fabricate a novel hybrid membrane by a layer-by-layer self-assembly method. The optimal membrane manufacturing conditions, including assembly time (10 min), Hmim/Zn molar ratio (8:1), and optimal layer number (three layers), were thoroughly investigated for cutting-off ofloxacin in water filtration.

Unlocking a Type-II CoO@BiVO Heterostructure for Wastewater Purification.

Developing a semiconductor-based heterostructure photoanode is crucial in improving the photoelectrocatalytic (PEC) efficiency for degrading refractory organic pollutants. Nevertheless, the PEC performance of the photoanodes is usually restricted by electron/hole pair recombination, oxygen evolution, and slow electron transfer. Herein, a novel CoO@BiVO nanowire array film (Ti/CoO@BiVO) with n-type semiconductor characteristics was prepared via a straightforward hydrothermal method.