Balancing methane emission and alkalinity conservation: Insights from mineral amendments in coastal sediments.

With global climate warming and ocean acidification, mineral amendments in coastal areas have emerged as a promising strategy to bolster carbon sinks and alkalinity. However, most research has predominantly focused on carbon dioxide (CO) absorption, with limited exploration of methane (CH) reduction despite its more potent greenhouse effect. To address this gap, our study conducted a microcosm manipulative experiment employing coastal wetlands sediments to elucidate the regulatory effects of various mineral amendments on greenhouse gas emissions (including CO and CH) and seawater alkalinity.

Responses of depth-dependence of C:N:P stoichiometry to check dam in mangrove wetlands.

Carbon (C) sequestration and nitrogen (N) and phosphorus (P) deposition in mangrove wetlands are significant for global climate regulation and the removal of marine nutrient pollutant. To protect and restore mangroves, numerous check dams have been implemented within mangrove wetlands; however, the influence of these check dams on C, N, and P content, stoichiometry, and their depth-dependence remains largely unexplored. To establish a causal relationship between the check dams and C and nutrient variations, we first determined soil deposition depth post-check dam construction in both a natural mangrove and a neighboring check dam-affected mangrove.

Developing the Short Form of the Survey on Social and Emotional Skills (SSES-SF).

Given the critical role of socio-emotional skills in students' academic success, psychological well-being, and other critical life outcomes, the Organization for Economic Cooperation and Development (OECD) developed the Survey on Social and Emotional Skills (SSES) to measure these skills among school-age students. However, the broad conceptual scope of socio-emotional skills necessitated the use of a large number of items (i.e.

Wildfire Smoke: Health Effects, Mechanisms, and Mitigation.

Wildfires are becoming more frequent and intense on a global scale, raising concerns about their acute and long-term effects on human health. We conducted a systematic review of the current epidemiological evidence on wildfire health risks and a meta-analysis to investigate the association between wildfire smoke exposure and various health outcomes. We discovered that wildfire smoke increases the risk of premature deaths and respiratory morbidity in the general population.

A global assessment of mangrove soil organic carbon sources and implications for blue carbon credit.

Mangroves can retain both autochthonous and allochthonous marine and/or terrestrial organic carbon (OC) in sediments. Accurate quantification of these OC sources is essential for the proper allocation of blue C credits. Here, we conduct a global-scale analysis of sediments autochthonous and allochthonous OC contributions in estuarine and marine mangroves using stable isotopes.

Ethanolic extraction and GC-MS analysis of antioxidant and anticancer bioactive compounds from and .

Bioactive components used to treat human ailments are abundant in medicinal plants. and have therapeutic properties due to the presence of many phytonutrients. Gas chromatography-mass spectrometry (GC-MS) was used to evaluate the properties of the antioxidant and anticancer bioactive components found in the ethanolic extracts of and leaves.

Early-life ozone exposure and childhood otitis media: Unveiling critical windows of risk.

Background: Despite increasing evidence of a strong correlation between air pollution and otitis media (OM), the impact of early-life ozone (O) exposure on the development of OM in children remains uncertain.

Objectives: To explore the connection between early-life O exposure and OM, and to identify the critical time period(s) during which O exposure significantly influences the development of OM in children.

Methods: We conducted a study involving 8689 children living in Changsha, China.

Childhood Helicobacter pylori infection: Impacts of environmental exposures and parental stress.

Background: Helicobacter pylori infection (HPI) is extremely common in the world, particularly in less developed areas, but the primary causes of childhood HPI are unspecified.

Objectives: To determine the influences of exposure to home environmental factors (HEFs), outdoor air pollutants (OAPs), and parental stress (PS), as well as their interactions on children's HPI.

Methods: We implemented a retrospective cohort study with 8689 preschoolers from nine districts at Changsha, China, was conducted using questionnaires to collect data of health and HEFs.

[Treatment of hypoxia-induced ED in high-altitude areas by transcutaneous low-frequency electrical stimulation based on the parameters obtained from visualized precision electrophysiological diagnosis].

Objective: To investigate the effects of visualized precision electrophysiological diagnosis and transcutaneous low-frequency electrical stimulation (TES) on hypoxia-induced ED in high-altitude areas.

Methods: This study included 152 ED patients from high-altitude hypoxic areas treated by TES based on the parameters obtained from visualized precision electrophysiological diagnosis. We followed up the patients for 1 to 3 months and compared their IIEF-5 scores, nocturnal penile tumescence and rigidity (NPTR) and infrared thermal metabolic technology (TMT)-based temperature of the whole body and diseased parts before and after treatment.

The JAK-STAT pathway: from structural biology to cytokine engineering.

The Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway serves as a paradigm for signal transduction from the extracellular environment to the nucleus. It plays a pivotal role in physiological functions, such as hematopoiesis, immune balance, tissue homeostasis, and surveillance against tumors. Dysregulation of this pathway may lead to various disease conditions such as immune deficiencies, autoimmune diseases, hematologic disorders, and cancer.

Designing intelligent bioorthogonal nanozymes: Recent advances of stimuli-responsive catalytic systems for biomedical applications.

Bioorthogonal nanozymes have emerged as a potent tool in biomedicine due to their unique ability to perform enzymatic reactions that do not interfere with native biochemical processes. The integration of stimuli-responsive mechanisms into these nanozymes has further expanded their potential, allowing for controlled activation and targeted delivery. As such, intelligent bioorthogonal nanozymes have received more and more attention in developing therapeutic approaches.

Responses of soil organic carbon compounds to phosphorus addition between tropical monoculture and multispecies forests.

Tropical forests are sensitive to nitrogen (N) and phosphorus (P) availability, and under nutrient application the variation of soil organic carbon (SOC) preserving mechanism remains to be explored. To reveal the forest-specific SOC preservation via biochemical selection in response to nutrient application, we investigated a monoculture (Acacia plantation) and a multispecies forest both with chronic fertilization in subtropical regions, and measured specific fingerprints of plant- and microbial-derived C compounds. In addition, to quantify the effect of P application on SOC content among tropical forests, we conducted a meta-analysis by compiling 125 paired measurements in field experiments from 62 studies.

Photophobia and Visual Triggers in Vestibular Migraine.

Introduction: Vestibular migraine (VM) is a prevalent vestibular disorder characterized by episodic vertigo. However, the relationship between photophobia and visual triggers in VM remains unexplored. We investigated the correlation of photophobia during the VM attack with interictal photosensitivity and visually triggering dizziness in patients with VM.

Enhancement of microbial community dynamics and metabolism in compost through ammonifying cultures inoculation.

The efficient use of livestock and poultry manure waste has become a global challenge, with microorganisms playing an important role. To investigate the impact of novel ammonifying microorganism cultures (NAMC) on microbial community dynamics and carbon and nitrogen metabolism, five treatments [5% (v/w) sterilized distilled water, Amm-1, Amm-2, Amm-3, and Amm-4] were applied to cow manure compost. Inoculation with NAMC improved the structure of bacterial and fungal communities, enriched the populations of the functional microorganisms, enhanced the role of specific microorganisms, and promoted the formation of tight modularity within the microbial network.

Small molecule drug discovery targeting the JAK-STAT pathway.

The Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway functions as a central hub for transmitting signals from more than 50 cytokines, playing a pivotal role in maintaining hematopoiesis, immune balance, and tissue homeostasis. Dysregulation of this pathway has been implicated in various diseases, including immunodeficiency, autoimmune conditions, hematological disorders, and certain cancers. Proteins within this pathway have emerged as effective therapeutic targets for managing these conditions, with various approaches developed to modulate key nodes in the signaling process, spanning from receptor engagement to transcription factor activation.

High humidity and NO co-exposure exacerbates allergic asthma by increasing oxidative stress, inflammatory and TRP protein expressions in lung tissue.

Allergic asthma is a chronic inflammatory airway disease with a high mortality rate and a rapidly increasing prevalence in recent decades that is closely linked to environmental change. Previous research found that high humidity (HH) and the traffic-related air pollutant NO both aggregated allergic asthma. Their combined effect and mechanisms on asthma exacerbation, however, are unknown.

Spartina alterniflora invasion benefits blue carbon sequestration in China.

Spartina alterniflora has rapidly and extensively encroached on China's coastline over the past decades. Among the coastal areas invaded by S. alterniflora, at most 93% are mudflats.

Children's food allergy: Effects of environmental influences and antibiotic use across critical developmental windows.

Background: Increasing studies linked outdoor air pollution (OAP), indoor environmental factors (IEFs), and antibiotics use (AU) with the first wave of allergies (i.e., asthma, allergic rhinitis, and eczema), yet the role of their exposures on children's second wave of allergy (i.