Corrigendum: Long non-coding RNA SNHG1 regulates the Wnt/β-catenin and PI3K/AKT/mTOR signaling pathways EZH2 to affect the proliferation, apoptosis, and autophagy of prostate cancer cell.

[This corrects the article DOI: 10.3389/fonc.2020.

Decoding the Ferroptosis-Related Gene Signatures and Immune Infiltration Patterns in Ovarian Cancer: Bioinformatic Prediction Integrated with Experimental Validation.

Background: Ovarian cancer is a type of gynecological cancer with extremely high fatality rate. Ferroptosis, an iron-dependent regulated cell death, inhibits the immune infiltration of tumor cells. Therefore, it is worthwhile to explore the effects of ferroptosis-related gene signatures and immune infiltration patterns on the clinical prognosis of ovarian cancer.

Cutting-edge and topical issues in the treatment of breast cancer with traditional Chinese medicine based on CiteSpace bibliometric analysis.

Background: Breast cancer poses a significant health threat to women, marked by high incidence and mortality rates. Although modern treatment primarily involves surgery and chemotherapy, which may reduce quality of life, limited analysis exists on the effects of traditional Chinese medicine (TCM) on this aspect. In this paper, bibliometric software was used to study the literature related to TCM in the treatment of breast cancer to provide researchers with new insights and directions for development.

A bibliometric analysis of hepatolenticular degeneration research in traditional Chinese medicine using CiteSpace and VOSviewer: A study protocol for systematic review.

Background: The purpose of this review was to analyze treatments for hepatolenticular degeneration (HLD) in traditional Chinese medicine (TCM), exploring the potential mechanisms and latest advances, as well as potential future directions.

Methods: We searched articles from the China National Knowledge Infrastructure, the Wanfang database, the Chinese Medical Journal Database, PubMed, the Cochrane Library, and Embase. We used CiteSpace (version 5.

A feasibility study of DNA ploidy analysis, HPV, and TCT for screening of cervical cancer: A retrospective study.

The present study aimed to evaluate the application of DNA ploidy analysis, human papillomavirus (HPV-DNA) test, and thin-prep cytologic test (TCT) for mass screening of cervical cancer (CC). A total of 13,830 patients who underwent both TCT and HPV-DNA tests from June 2021 to June 2022 were selected as study participants (10,107 patients from Shandong Provincial Hospital, 2447 patients from First People's Hospital of Tancheng County, and 1276 patients from Liaocheng People's Hospital). We also conducted a DNA ploidy analysis and compared the results.

[Characteristics of airway microbiome co-occurrence network in patients with type 2 and non-type 2 asthma].

To study the characteristics of the airway microbiome co-occurrence network in patients with type 2 and non-type 2 asthma. In a prospective study based on a cohort of asthma patients, respiratory induced sputum samples were collected from 55 asthma patients [25 males and 30 females, with a median age of 47.7 years (age range 34.

METTL3 improves the development of somatic cell nuclear transfer embryos through AURKB and H3S10ph in goats.

Developmental abnormalities are more common in somatic cell nuclear transfer (SCNT) embryos due to epigenetic barriers that occur during the maternal-to-zygotic transition (MZT). N6-methyladenosine (m6A) is an RNA epigenetic modification that plays a significant role in numerous biological processes. However, the relationship between m6A and SCNT embryonic development is largely unexplored.

Unveiling ultraviolet photodissociation dynamics of SiO from a laser-ablated supersonic beam with time-sliced ion velocity imaging.

SiO is a widespread molecule found in interstellar space, and its dissociation requires a substantial input of energy due to its high bond energy of 8.34 eV. The present study initially demonstrated across a broad range of ultraviolet (UV) wavelengths (243-288 nm) the one-photon and two-photon dissociation of SiO molecules, which were generated from the laser ablation of a Si rod colliding with an oxygen molecular beam.

Two rice cultivars recruit different rhizospheric bacteria to promote aboveground regrowth after mechanical defoliation.

Plants have evolved the ability to regrow after mechanical defoliation and environmental stresses. However, it is unclear whether and how defoliated plants exploit beneficial microbiota from the soil to promote aboveground regrowth. Here, we compared the defoliation-triggered changes in the root exudation and bacterial microbiome of two rice cultivars ( L .

Machine Learning-Driven Methods for Nanobody Affinity Prediction.

Because of their high affinity, specificity, and environmental stability, nanobodies (Nbs) have continuously received attention from the field of biological research. However, it is tough work to obtain high-affinity Nbs using experimental methods. In the current study, 12 machine learning algorithms were compared in parallel to explore the potential patterns between Nb-ligand affinity and eight noncovalent interactions.

Flowable Oxygen-Release Hydrogel Inhibits Bacteria and Treats Periodontitis.

Periodontitis, the chronic inflammation of the periodontal tissues caused by bacteria in plaque, is the leading cause of tooth loss in adults in the world. Currently, periodontitis is effectively treated with mechanical cleaning and the use of antibiotics. However, these treatments only temporarily remove plaque, which can rapidly proliferate and multiply in periodontal pockets over time.

Keep it accurate and robust: An enhanced nuclei analysis framework.

Accurate segmentation and classification of nuclei in histology images is critical but challenging due to nuclei heterogeneity, staining variations, and tissue complexity. Existing methods often struggle with limited dataset variability, with patches extracted from similar whole slide images (WSI), making models prone to falling into local optima. Here we propose a new framework to address this limitation and enable robust nuclear analysis.

Prediction of acute myeloid leukemia prognosis based on autophagy features and characterization of its immune microenvironment.

Background: Autophagy promotes the survival of acute myeloid leukemia (AML) cells by removing damaged organelles and proteins and protecting them from stress-induced apoptosis. Although many studies have identified candidate autophagy genes associated with AML prognosis, there are still great challenges in predicting the survival prognosis of AML patients. Therefore, it is necessary to identify more novel autophagy gene markers to improve the prognosis of AML by utilizing information at the molecular level.

The Impact of Cyberbullying Victimization on Internet Gaming Addiction Among College Students: The Mediating Roles of Basic Psychological Need Satisfaction and Frustration, and the Moderating Role of Parental Autonomy Support.

Purpose: Research on the relationship between cyberbullying victimization and Internet gaming addiction in China is limited, while the mechanisms underlying this association remain unclear. Based on the Self-Determination Theory, this study establishes a moderated mediation model to test the mediating roles of basic psychological need satisfaction and frustration between cyberbullying victimization and Internet gaming addiction, as well as the moderating role of parental autonomy support in this mediating effect.

Methods: 2819 college students were surveyed using self-reported questionnaires about cyberbullying victimization, basic psychological need satisfaction and frustration, parental autonomy support, and Internet gaming addiction.

Global research trends and hotspots in Parkinson's disease psychosis: a 25-year bibliometric and visual analysis.

Background: Parkinson's disease psychosis (PDP) is one of the most severe and disabling non-motor symptoms in the progression of Parkinson's disease (PD), significantly impacting the prognosis of PD patients. In recent years, there has been an increase in literature on PDP. However, bibliometrics has rarely been applied to PDP research.

Light curve parametrization of three rice ( L.) cultivars based on mechanistic models.

This study aimed to assess variations in leaf gas-exchange characteristics, leaf pigment contents, and some intrinsic traits of photosynthetic pigment molecules in three rice cultivars (cv. JR3015, Wufengyou3015, and Jifengyou3015) using mechanistic models. The findings revealed that chlorophyll content varied significantly among the three cultivars, but not maximum electron transport rate.

CRISPR-Cas9 screening identifies the role of FER as a tumor suppressor.

It is important to systematically identify tumor suppressor genes (TSGs) to improve our understanding of tumorigenesis and develop strategies for early diagnosis and mitigating disease progression. In the present study, we used an in vivo genome-wide clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated protein 9 (Cas9) screen and identified FPS/FES-related (FER) as a TSG. Single-cell RNA sequencing (scRNA-seq) revealed that normal cells with low FER expression exhibited elevated malignant transformation potential and stemness properties.

Chitosan and gelatin based sprayable hydrogels incorporating photothermal and long-acting antibiotic sterilization for infected wound management with shape adaptability.

Severe skin damage resulting from acute trauma is often accompanied by uncontrolled bleeding, microbial infections, and delayed wound healing. Herein, multifunctional sprayable hydrogels (CT-CS-ZIF@CIP Gel) were developed for wound management by incorporating antibacterial nanoplatforms (CT-CS-ZIF@CIP) into photocurable gels consisting of chitosan methacrylate and gallic acid grafted gelatin. The nanoplatform was initially constructed by sequentially loading CuSe (CS) and ciprofloxacin-decorated zeolitic imidazolate framework-8 (ZIF@CIP) onto Cu-doped Ti MOF (CT), in which CS served as a photothermal agent, ZIF enabled pH-responsive release of CIP, and CT acted as carriers for CS and ZIF@CIP.

Combined effects of different-sized microplastics and fluindapyr on earthworm: bioaccumulation, oxidative stress, histopathological responses and gut microbiota.

Soil is an important sink for microplastics (MPs) and pesticides. MPs can act as carriers for pesticides, thus induce direct and indirect effects on soil organisms. Fluindapyr (FIP), a novel succinate dehydrogenase inhibitors fungicides (SDHIs), may pose a serious threat to earthworms.

LLGL2 targets the Hedgehog signaling pathway to influence malignant progression of endometrial cancer.

Background: Endometrial cancer (EC) is a malignant tumor of the endometrial epithelium, with endometrial adenocarcinoma being the most common type. It has a good overall prognosis, but recurrence and metastasis are often associated with poorer outcomes. LLGL2 is closely linked to tumorigenesis; however, its in endometrial carcinoma is unknown.

Effect of jujube pulp on the quality of cream cheese product during storage.

Cheese is favored by foreign consumers for its remarkable nutritional profile and unique taste. However, Chinese consumers find it difficult to accept its strong flavor profile. Therefore, it is imperative to develop a cheese product that meets the flavor preferences of Chinese consumers.