Resting-state microstate dynamics abnormalities in children with ADHD and co-occurring sleep problems.

Objectives: Children with attention-deficit/hyperactivity disorder often experience sleep problems, exacerbating symptoms, and cognitive deficits. However, the neurophysiological mechanisms underlying such deficits remained unclear. This study aims to use resting-state microstate analysis to investigate the neurophysiological characteristics in children with ADHD and sleep problems and explore whether neurophysiological abnormalities are associated with sleep problems.

Multimodal assessment predicts cognitive impairment after aneurysmal subarachnoid hemorrhage: a prospective cohort study.

Background: Risk factors and mechanisms of cognitive impairment (CI) after aneurysmal subarachnoid hemorrhage (aSAH) are unclear. This study used a neuropsychological battery, MRI, ERP and CSF and plasma biomarkers to predict long-term cognitive impairment after aSAH.

Materials And Methods: 214 patients hospitalized with aSAH (n = 125) or unruptured intracranial aneurysms (UIA) (n = 89) were included in this prospective cohort study.

Revealing Crucial Influences of Boron Support on Regulating Geometric and Electronic Structures of 3D Catalyst for Hydrogen Evolution and Oxygen Reduction Reactions.

Building insights into the structure-performance relationship of catalysts has been emphasized recently. However, it remains a challenge due to catalysts' various and complex structures, especially the easily overlooked influence of the support material. Here, we reveal the crucial influences of boron introduction on synthesizing 3D carbon nanotube monoliths with embedded multistate Co metals, i.

Alterations of Oscillatory Activity and Cognitive Function After Aneurysmal Subarachnoid Hemorrhage.

Background: Aneurysmal subarachnoid hemorrhage (aSAH) can lead to cognitive impairment, but underlying neural mechanisms remain to be elucidated.

Materials And Methods: To predict long-term cognitive impairment after aSAH, resting electroencephalography (EEG) was measured in 112 patients hospitalized with a diagnosis of aSAH (n = 66) or unruptured intracranial aneurysms (UIA; controls) (n = 46). A neuropsychological battery was administered 8 to 24 months after discharge.

Radical prostatectomy without prostate biopsy based on a noninvasive diagnostic strategy: a prospective single-center study.

Background: Prostate biopsy is the most common approach for diagnosing prostate cancer (PCa); however, it has inherent limitations, such as the invasive procedure, postoperative complications, and false negative results. We aimed to provide a noninvasive diagnostic strategy for patients with highly suspected PCa and to evaluate the feasibility of performing biopsy-spared radical prostatectomy.

Methods: This prospective study included a total of 57 patients between November 10, 2022, and December 1, 2023.

Impaired Attention in Children with Obstructive Sleep Apnea: A Preliminary Study of Behavior Combined with Neuroelectrophysiology.

Objective: To investigate how attention is affected in children with obstructive sleep apnea (OSA) using the attention network test (ANT) combined with event-related potential (ERP) and time-frequency analysis.

Methods: Eighty-seven children aged 6-11 years with symptoms of snoring or mouth breathing during sleep were recruited from the Sleep Center of Beijing Children's Hospital from May to July, 2023. All participants completed the Mini-mental State Examination and Attention Deficit Hyperactivity Disorder rating scale.

Associations of Physical Activity with Long-Term Mortality Among Peripheral Artery Disease Patients: A Population-Based Cohort Study.

Background: To investigate the relationship between physical activity and risk of all-cause and cardiovascular disease (CVD) mortality in patients with peripheral artery disease (PAD).

Methods: We recruited 561 PAD cases of National Health and Nutrition Examination Survey from 1999 to 2004 and linked mortality data through December 31, 2019. We explored the effect of aerobic physical activity and muscle-strengthening activity on the risk of all-cause and CVD mortality employing cox proportional hazard ratios (HRs) with 95% confidence intervals (CIs) from 1999 to 2019.

SIRT1 regulates cigarette smoke extract‑induced alveolar macrophage polarization and inflammation by inhibiting the TRAF6/NLRP3 signaling pathway.

M1 macrophages activated by cigarette smoke extract (CSE) serve a pro‑inflammatory role in chronic obstructive pulmonary disease (COPD). The expression of silent information regulator 1 (SIRT1) is decreased in the alveolar macrophages of patients with COPD. However, whether SIRT1 is involved in COPD by regulating macrophage polarization remains unknown.

Early Impairment of Face Perception in Post-Stroke Depression: An ERP Study.

Face recognition is an important cognitive function of the human brain. Post stroke depression (PSD) is a common mental complication after stroke, which has a serious impact on individual physical function recovery and quality of life. This study aims to explore the face perception characteristics of PSD through electrophysiological indicators N170 and VPP, and provide an objective basis for the early evaluation of facial cognitive dysfunction in PSD.

Staphylococcus aureus SaeRS impairs macrophage immune functions through bacterial clumps formation in the early stage of infection.

The Staphylococcus aureus (S. aureus) SaeRS two-component system (TCS) regulates over 20 virulence factors. While its impact on chronic infection has been thoroughly discussed, its role in the early stage of infection remains elusive.

Comparative analysis of ecological sensitivity assessment using the coefficient of variation method and machine learning.

Ecological sensitivity is an essential indicator for measuring the ecological environment's level, and its assessment results have significant reference value for regional ecological environment protection and resource development and utilization. Taking Xifeng County as the study area, we selected a total of 12 assessment factors in terms of ecological environment, geological environment, and human environment, including average annual rainfall, average annual temperature, average annual wind speed, river density, vegetation coverage, soil erodibility, elevation, slope, geological disaster susceptibility, road density, land use, and night light index, and explored the spatial distribution patterns of ecological sensitivities and the characteristics of the differences in the study area based on the coefficient of variation method and machine learning. The results show that the overall spatial distribution pattern of ecological sensitivity in Xifeng County shows a low sensitivity in the north and a high sensitivity in the south.

Dual-strategy engineered nickel phosphide for achieving efficient hydrazine-assisted hydrogen production in seawater.

Electrocatalytic hydrogen production in seawater to alleviate freshwater shortage pressures is promising, but is hindered by the sluggish oxygen evolution reaction and detrimental chloride electrochemistry. Herein, a dual strategy approach of Fe-doping and CeO-decoration in nickel phosphide (Fe-NiP/CeO) is rationally designed to achieve superior bifunctional catalytic performance for the hydrogen evolution reaction (HER) and hydrazine oxidation reaction (HzOR) in seawater. Notably, the two-electrode Fe-NiP/CeO-based hybrid seawater electrolyzer realizes energy-efficient and chlorine-free hydrogen production with ultralow cell voltages of 0.

Spatially Mediated Paper Reactors for On-Site Multicoded Encryption.

This report develops a point-of-use chemical trigger and applies it to a dual-functional chemical encryption chip that enables manual and digital identification with enhanced coding security levels suitable for on-site information verification. The concept relies on conducting continuous chemical synthesis and chromatographic separation of specified compounds on a paper device in a straightforward sketch. In addition to single-step chemical reactions, cascade syntheses and operations involving components of distinct mobilities are also demonstrated.

A hierarchical CoS/Ni(OH) heterostructure as a bifunctional electrocatalyst for urea-assisted energy-efficient hydrogen production.

We report hierarchical CoS/Ni(OH)/NF heterostructure nanorod arrays, which manifest superior bifunctional catalytic activities for the HER and UOR due to amorphous Ni(OH), synergistic effect of multiple components and self-supported structure. The CoS/Ni(OH)/NF-based urea electrolyzer requires a low cell voltage of 1.485 V to deliver 10 mA cm, which is obviously lower than that needed in water electrolysis.

Effects of different substrates on the growth and yield of .

Seven different substrates were prepared by mixing red soil, humus and river sand in different volume ratios and the growth and yield of bulbils in different substrates was investigated. The growth of seedlings were tracked during the reproductive period, with measurements taken of indicators such as petiole length, petiole basal diameter and leaf size during the late period of leaf expansion. Number of surviving plants, weights and sizes of corms, and leaf bulbils were recorded after lodging.

EPAT: a user-friendly MATLAB toolbox for EEG/ERP data processing and analysis.

Background: At the intersection of neural monitoring and decoding, event-related potential (ERP) based on electroencephalography (EEG) has opened a window into intrinsic brain function. The stability of ERP makes it frequently employed in the field of neuroscience. However, project-specific custom code, tracking of user-defined parameters, and the large diversity of commercial tools have limited clinical application.

Classification and transfer learning of sleep spindles based on convolutional neural networks.

Background: Sleep plays a critical role in human physiological and psychological health, and electroencephalography (EEG), an effective sleep-monitoring method, is of great importance in revealing sleep characteristics and aiding the diagnosis of sleep disorders. Sleep spindles, which are a typical phenomenon in EEG, hold importance in sleep science.

Methods: This paper proposes a novel convolutional neural network (CNN) model to classify sleep spindles.

EEG analysis in patients with schizophrenia based on microstate semantic modeling method.

Introduction: Microstate analysis enables the characterization of quasi-stable scalp potential fields on a sub-second timescale, preserving the temporal dynamics of EEG and spatial information of scalp potential distributions. Owing to its capacity to provide comprehensive pathological insights, it has been widely applied in the investigation of schizophrenia (SCZ). Nevertheless, previous research has primarily concentrated on differences in individual microstate temporal characteristics, neglecting potential distinctions in microstate semantic sequences and not fully considering the issue of the universality of microstate templates between SCZ patients and healthy individuals.

The efficacy and safety of ciprofol and propofol in patients undergoing colonoscopy: A double-blind, randomized, controlled trial.

Study Objective: Propofol is a commonly utilized anesthetic for painless colonoscopy, but its usage is occasionally limited due to its potential side effects, including cardiopulmonary suppression and injection pain. To address this limitation, the novel compound ciprofol has been proposed as a possible alternative for propofol. This study sought to determine whether there are any differences in the safety and efficacy of propofol and ciprofol for painless colonoscopy.