Efficacy of Pulp Revascularization in the Treatment of Apical Periodontitis in Mature Necrotic Teeth: An Umbrella Review.

This umbrella review evaluated systematic reviews in clinical studies on pulp revascularisation in permanent mature necrotic teeth to determine their effectiveness in treating or preventing apical periodontitis. Seven of 294 articles retrieved from PubMed, LILACS, SciELO, Embase, Scopus, Web of Science, Cochrane and DANS Easy databases were included. The most used pulp revascularisation techniques were blood clots associated or not with platelet-poor plasma and umbilical cord mesenchymal stem cells.