Secretory immunoglobulin A concentration in non-stimulated and stimulated saliva in relation to the status of smoking.

Introduction: Secretory immunoglobulin A (sIgA) is a dominant immunoglobulin in the saliva. It is the first line of defense against microorganisms.

Aim Of The Study: Analysis of secretory immunoglobulin A concentration in non-stimulated and stimulated saliva.

Stimulated and non-stimulated saliva as biological material in the assessment of cotinine concentration.

Introduction: A biomarker of the exposure to the tobacco smoke is cotinine - a nicotine metabolite with a half-life about 16 hours. Analysis of cotinine concentration in biological material allows objective assessment of the cigarette smoking status and environmental exposure to the tobacco smoke.

Aim Of The Study: The aim of the study was evaluation of the influence of method of saliva collection: stimulated or non-stimulated one by chewing a paraffin cube on cotinine concentration in the saliva as well as the analysis of the obtained cotinine values depending on the status of cigarette smoking.

[Cotinine concentration in the saliva in relation to oral hygiene procedures].

Cotinine is a biomarker of the exposure to the tobacco smoke, nicotine metabolite with half-life in the saliva which is 17 hours. Assessment of cotinine concentration enables among others verification of the questionnaire data as well as evaluation of both smokers and non-smokers exposure to the tobacco smoke. Practicing proper oral hygiene procedures is an essential factor of the prophylaxis of dental caries and periodontal diseases which influence general health state.

[Lymphocyte activation markers in patients with ovarian cancer].

Introduction: The process of T cells activation is necessary for the performance of the defense functions. Successful activation depends on direct lymphocyte - antigen-presenting cell contact and signal transmission to the lymphocyte. Activated T cells exhibit surface expression of molecules such as CD69, CD25 and HLA-DR.